APR03501G

CDKN2C antibody from Leading Biology
INK4C, p18
Western blot
Recommended by provider
Immunohistochemistry
Recommended by provider

Antibody data

Product number
APR03501G
Provider
Leading Biology
Product name
CDKN2C Antibody (C-term)
Provider product page
Leading Biology - APR03501G
Antibody type
Polyclonal
Description
The protein encoded by this gene is a member of the INK4family of cyclin-dependent kinase inhibitors. This protein has beenshown to interact with CDK4 or CDK6, and prevent the activation ofthe CDK kinases, thus function as a cell growth regulator thatcontrols cell cycle G1 progression. Ectopic expression of this genewas shown to suppress the growth of human cells in a manner thatappears to correlate with the presence of a wild-type RB1 function.Studies in the knockout mice suggested the roles of this gene inregulating spermatogenesis, as well as in suppressingtumorigenesis. Two alternatively spliced transcript variants ofthis gene, which encode an identical protein, have been reported.
Reactivity
Human, Mouse
Host
Rabbit
Storage
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Provider Type Product Number
- No reagents -