BS4873

antibody from Bioworld Technology, Inc
Targeting: SMAD1 JV4-1, MADH1, MADR1
Provider product page for BS4873
Western blot
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
BS4873 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Smad1 (phospho S187) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human Smad1 around the phosphorylation site of Serine 187.
Description
Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGFÉÇ/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MadH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFÉÇ and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFÉÇ signaling by interfering with TGFÉÇ-mediated phosphorylation of other Smad family members.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SMAD1 protein structure - BS4873 shown in red.