DCABH-1874

antibody from Creative Diagnostics

Targeting: SMAD1 JV4-1, MADH1, MADR1

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

DCABH-1874

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DCABH-1874, RRID:AB_2475812

Product name

Rabbit Anti-Human Smad1 monoclonal antibody, clone TE3101

Antibody type

Monoclonal

Description

Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGFÉÇ/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MADH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFÉÇ and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFÉÇ signaling by interfering with TGFÉÇ-mediated phosphorylation of other Smad family members.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

TE3101

Vial size

100 _l

Storage

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.