Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB1984 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB1984, RRID:AB_1578119
- Product name
- NOTCH3 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of NOTCH3.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Mutation of the Notch 3 gene in a Thai cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy family.
Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis.
Investigation of Notch3 as a candidate gene for bipolar disorder using brain hyperintensities as an endophenotype.
Suwanwela N, Srikiatkhachorn A, Tangwongchai S, Phanthumchina K, Suwanwela N
Journal of the Medical Association of Thailand = Chotmaihet thangphaet 2003 Feb;86(2):178-82
Journal of the Medical Association of Thailand = Chotmaihet thangphaet 2003 Feb;86(2):178-82
Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis.
Bellavia D, Campese AF, Checquolo S, Balestri A, Biondi A, Cazzaniga G, Lendahl U, Fehling HJ, Hayday AC, Frati L, von Boehmer H, Gulino A, Screpanti I
Proceedings of the National Academy of Sciences of the United States of America 2002 Mar 19;99(6):3788-93
Proceedings of the National Academy of Sciences of the United States of America 2002 Mar 19;99(6):3788-93
Investigation of Notch3 as a candidate gene for bipolar disorder using brain hyperintensities as an endophenotype.
Ahearn EP, Speer MC, Chen YT, Steffens DC, Cassidy F, Van Meter S, Provenzale JM, Weisler RH, Krishnan KR
American journal of medical genetics 2002 Aug 8;114(6):652-8
American journal of medical genetics 2002 Aug 8;114(6):652-8
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of NIH/3T3 cell lysate (15 ug/lane) with NOTCH3 polyclonal antibody (Cat # PAB1984).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human breast cancer tissue reacted with NOTCH3 polyclonal antibody (Cat # PAB1984) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)