Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- ELISA [1]
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- Product number
- H00004854-M01 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00004854-M01, RRID:AB_546554
- Product name
- Mouse Monoclonal Notch-3 Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. NOTCH3 - Notch homolog 3 (Drosophila)
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Serum amyloid P component: A novel potential player in vessel degeneration in CADASIL.
N-acetylcysteine negatively regulates Notch3 and its malignant signaling.
Von Willebrand factor inhibits mature smooth muscle gene expression through impairment of Notch signaling.
Bidirectional encroachment of collagen into the tunica media in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.
Functional analysis of the Notch ligand Jagged1 missense mutant proteins underlying Alagille syndrome.
Transendocytosis is impaired in CADASIL-mutant NOTCH3.
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy affecting an African American man: identification of a novel 15-base pair NOTCH3 duplication.
Thrombospondin 2 potentiates notch3/jagged1 signaling.
Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer.
Nagatoshi A, Ueda M, Ueda A, Tasaki M, Inoue Y, Ma Y, Masuda T, Mizukami M, Matsumoto S, Kosaka T, Kawano T, Ito T, Ando Y
Journal of the neurological sciences 2017 Aug 15;379:69-76
Journal of the neurological sciences 2017 Aug 15;379:69-76
N-acetylcysteine negatively regulates Notch3 and its malignant signaling.
Zhang X, Wang YN, Zhu JJ, Liu XX, You H, Gong MY, Zou M, Cheng WH, Zhu JH
Oncotarget 2016 May 24;7(21):30855-66
Oncotarget 2016 May 24;7(21):30855-66
Von Willebrand factor inhibits mature smooth muscle gene expression through impairment of Notch signaling.
Meng H, Zhang X, Lee SJ, Wang MM
PloS one 2013;8(9):e75808
PloS one 2013;8(9):e75808
Bidirectional encroachment of collagen into the tunica media in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.
Dong H, Blaivas M, Wang MM
Brain research 2012 May 25;1456:64-71
Brain research 2012 May 25;1456:64-71
Functional analysis of the Notch ligand Jagged1 missense mutant proteins underlying Alagille syndrome.
Tada M, Itoh S, Ishii-Watabe A, Suzuki T, Kawasaki N
The FEBS journal 2012 Jun;279(12):2096-107
The FEBS journal 2012 Jun;279(12):2096-107
Transendocytosis is impaired in CADASIL-mutant NOTCH3.
Watanabe-Hosomi A, Watanabe Y, Tanaka M, Nakagawa M, Mizuno T
Experimental neurology 2012 Jan;233(1):303-11
Experimental neurology 2012 Jan;233(1):303-11
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy affecting an African American man: identification of a novel 15-base pair NOTCH3 duplication.
Lee SJ, Meng H, Elmadhoun O, Blaivas M, Wang MM
Archives of neurology 2011 Dec;68(12):1584-6
Archives of neurology 2011 Dec;68(12):1584-6
Thrombospondin 2 potentiates notch3/jagged1 signaling.
Meng H, Zhang X, Hankenson KD, Wang MM
The Journal of biological chemistry 2009 Mar 20;284(12):7866-74
The Journal of biological chemistry 2009 Mar 20;284(12):7866-74
Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer.
Park JT, Shih IeM, Wang TL
Cancer research 2008 Nov 1;68(21):8852-60
Cancer research 2008 Nov 1;68(21):8852-60
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- ELISA: Notch-3 Antibody (1G5) [H00004854-M01] - Detection limit for recombinant GST tagged NOTCH3 is approximately 0.03ng/ml as a capture antibody.