Antibody data
- Antibody Data
- Antigen structure
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- Product number
- AMM01389G - Provider product page
- Provider
- Leading Biology
- Product name
- CD106 / VCAM1 (Activated Endothelial Cell Marker) Antibody - With BSA and Azide
- Antibody type
- Monoclonal
- Description
- Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.
- Reactivity
- Human
- Host
- Mouse
- Antibody clone number
- 1.4C3
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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