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- References [2]
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- Western blot [1]
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- Product number
- GTX63013 - Provider product page
- Provider
- GeneTex
- Product name
- Topoisomerase 1 antibody [EPR5375], N-term
- Antibody type
- Monoclonal
- Antigen
- A synthetic peptide corresponding to residues on the N-terminus in human Topoisomerase 1 was used as an immunogen.
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100µl
- Storage
- Store at -20 °C. Stable for 12 months from date of receipt.
Submitted references Topoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms.
Topoisomerase 1 inhibition reversibly impairs synaptic function.
Mabb AM, Simon JM, King IF, Lee HM, An LK, Philpot BD, Zylka MJ
PloS one 2016;11(5):e0156439
PloS one 2016;11(5):e0156439
Topoisomerase 1 inhibition reversibly impairs synaptic function.
Mabb AM, Kullmann PH, Twomey MA, Miriyala J, Philpot BD, Zylka MJ
Proceedings of the National Academy of Sciences of the United States of America 2014 Dec 2;111(48):17290-5
Proceedings of the National Academy of Sciences of the United States of America 2014 Dec 2;111(48):17290-5
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Western blot analysis on (A) Jurkat, (B) MCF-7, (C) SW480, and (D) K562 cell lysates using anti-Topoisomerase 1 rabbit mAb (cat. #GTX63013).
- Validation comment
- WB
