ADI-AAM-050-E

antibody from Enzo Life Sciences

Targeting: XIAP API3, BIRC4, hILP, ILP-1

Western blot (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ADI-AAM-050-E

Provider

Enzo Life Sciences

Proper citation

Enzo Life Sciences Cat#ADI-AAM-050-E, RRID:AB_2039687

Product name

XIAP monoclonal antibody (2F1)

Antibody type

Monoclonal

Antigen

Recombinant full length protein

Description

Protein A affinity purified.

Reactivity

Human, Mouse

Host

Mouse

Isotype

IgG

Antibody clone number

2F1

Vial size

100 μg

Storage

-20°C

References

Submitted references

Silibinin sensitizes human glioma cells to TRAIL-mediated apoptosis via DR5 up-regulation and down-regulation of c-FLIP and survivin.

Son YG, Kim EH, Kim JY, Kim SU, Kwon TK, Yoon AR, Yun CO, Choi KS
Cancer research 2007 Sep 1;67(17):8274-84

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Interaction between XIAP and Smac/DIABLO in the mouse brain after transient focal cerebral ischemia.

Saito A, Hayashi T, Okuno S, Ferrand-Drake M, Chan PH
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003 Sep;23(9):1010-9

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Role of Smac in human leukaemic cell apoptosis and proliferation.

Jia L, Patwari Y, Kelsey SM, Srinivasula SM, Agrawal SG, Alnemri ES, Newland AC
Oncogene 2003 Mar 20;22(11):1589-99

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XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway.

Yamaguchi K, Nagai S, Ninomiya-Tsuji J, Nishita M, Tamai K, Irie K, Ueno N, Nishida E, Shibuya H, Matsumoto K
The EMBO journal 1999 Jan 4;18(1):179-87

Immunocytochemistry

Supportive validation

Submitted by

Enzo Life Sciences (provider)

Main image

Experimental details

Western blot analysis of Jurkat (1), Raji (2), HeLa (3), WR19L (4) and PC12 (5) cells, probed with XIAP mAb (2F1).