BS1787

antibody from Bioworld Technology, Inc
Targeting: PLCB3
Provider product page for BS1787
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS1787 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS1787, RRID:AB_1662086
Product name
PLC ÉÇ3 (L532) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 500-550 of Human PLC ÉÇ3.
Description
A total of eight mammalian PLC isozymes have been described (PLC ÉÇ1, PLC ÉÇ2, PLC ÉÇ3, PLC ÉÇ4, PLC ÎÛ1, PLC ÎÛ2, PLC Ñ´1 and PLC Ñ´2) with molecular weights ranging from 85 to 150 kDa. The ÎÛ-type enzymes are unique in that they contain SH2 and SH3 domains. Moreover, the two ÎÛ-type enzymes, but not the ÉÇ and Ñ´ isozymes, are subject to activation by a number of protein tyrosine kinases which associate with their SH2 domains and induce their activation by phosphoryation. In contrast, activation of PLC ÉÇ1, PLC ÉÇ2 and PLC ÉÇ3 is mediated by the Ï« subunits of the Gq class of heterotrimeric G proteins and by certain ÉÇÎÛ G protein subunits. The regulatory mechanisms for PLC Ñ´1 and PLC Ñ´2 are as yet not resolved.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PLCB3 protein structure - BS1787 shown in red.