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- Antibody Data
- Antigen structure
- References [11]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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- Product number
- 14155-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14155-1-AP, RRID:AB_2231625
- Product name
- FKBP5 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FKBP5 antibody (Cat. #14155-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Blood-Based Epigenetic Markers of FKBP5 Gene Methylation in Patients With Dilated Cardiomyopathy.
IRF4 in Skeletal Muscle Regulates Exercise Capacity via PTG/Glycogen Pathway.
Downregulation of PD-L1 via FKBP5 by celecoxib augments antitumor effects of PD-1 blockade in a malignant glioma model.
MicroRNA-99a is a Potential Target for Regulating Hypothalamic Synaptic Plasticity in the Peri/Postmenopausal Depression Model.
Developmental nicotine exposure elicits multigenerational disequilibria in proBDNF proteolysis and glucocorticoid signaling in the frontal cortices, striata, and hippocampi of adolescent mice.
Elective caesarean delivery and offspring's cognitive impairment: Implications of methylation alteration in hippocampus glucocorticoid signaling genes.
Regulators of glucocorticoid receptor function in an animal model of depression and obesity.
A severe mouse model of spinal muscular atrophy develops early systemic inflammation.
USP49 negatively regulates tumorigenesis and chemoresistance through FKBP51-AKT signaling.
The co-chaperones Fkbp4/5 control Argonaute2 expression and facilitate RISC assembly.
Cell intrinsic role of COX-2 in pancreatic cancer development.
Wada K, Misaka T, Yokokawa T, Kimishima Y, Kaneshiro T, Oikawa M, Yoshihisa A, Takeishi Y
Journal of the American Heart Association 2021 Nov 2;10(21):e021101
Journal of the American Heart Association 2021 Nov 2;10(21):e021101
IRF4 in Skeletal Muscle Regulates Exercise Capacity via PTG/Glycogen Pathway.
Zhu X, Yao T, Wang R, Guo S, Wang X, Zhou Z, Zhang Y, Zhuo X, Wang R, Li JZ, Liu T, Kong X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Oct;7(19):2001502
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Oct;7(19):2001502
Downregulation of PD-L1 via FKBP5 by celecoxib augments antitumor effects of PD-1 blockade in a malignant glioma model.
Yamaguchi I, Nakajima K, Shono K, Mizobuchi Y, Fujihara T, Shikata E, Yamaguchi T, Kitazato K, Sampetrean O, Saya H, Takagi Y
Neuro-oncology advances 2020 Jan-Dec;2(1):vdz058
Neuro-oncology advances 2020 Jan-Dec;2(1):vdz058
MicroRNA-99a is a Potential Target for Regulating Hypothalamic Synaptic Plasticity in the Peri/Postmenopausal Depression Model.
Yang J, Zhang L, Cao LL, Qi J, Li P, Wang XP, Sun XL
Cells 2019 Sep 13;8(9)
Cells 2019 Sep 13;8(9)
Developmental nicotine exposure elicits multigenerational disequilibria in proBDNF proteolysis and glucocorticoid signaling in the frontal cortices, striata, and hippocampi of adolescent mice.
Buck JM, O'Neill HC, Stitzel JA
Biochemical pharmacology 2019 Oct;168:438-451
Biochemical pharmacology 2019 Oct;168:438-451
Elective caesarean delivery and offspring's cognitive impairment: Implications of methylation alteration in hippocampus glucocorticoid signaling genes.
Huang K, Hu Y, Sun Y, Yu Z, Liu W, Zhu P, Tao F
Brain research bulletin 2019 Jan;144:108-121
Brain research bulletin 2019 Jan;144:108-121
Regulators of glucocorticoid receptor function in an animal model of depression and obesity.
Kurek A, Głombik K, Detka J, Basta-Kaim A, Kubera M, Lasoń W, Budziszewska B
Journal of neuroendocrinology 2018 Mar 9;
Journal of neuroendocrinology 2018 Mar 9;
A severe mouse model of spinal muscular atrophy develops early systemic inflammation.
Wan B, Feng P, Guan Z, Sheng L, Liu Z, Hua Y
Human molecular genetics 2018 Dec 1;27(23):4061-4076
Human molecular genetics 2018 Dec 1;27(23):4061-4076
USP49 negatively regulates tumorigenesis and chemoresistance through FKBP51-AKT signaling.
Luo K, Li Y, Yin Y, Li L, Wu C, Chen Y, Nowsheen S, Hu Q, Zhang L, Lou Z, Yuan J
The EMBO journal 2017 May 15;36(10):1434-1446
The EMBO journal 2017 May 15;36(10):1434-1446
The co-chaperones Fkbp4/5 control Argonaute2 expression and facilitate RISC assembly.
Martinez NJ, Chang HM, Borrajo Jde R, Gregory RI
RNA (New York, N.Y.) 2013 Nov;19(11):1583-93
RNA (New York, N.Y.) 2013 Nov;19(11):1583-93
Cell intrinsic role of COX-2 in pancreatic cancer development.
Hill R, Li Y, Tran LM, Dry S, Calvopina JH, Garcia A, Kim C, Wang Y, Donahue TR, Herschman HR, Wu H
Molecular cancer therapeutics 2012 Oct;11(10):2127-37
Molecular cancer therapeutics 2012 Oct;11(10):2127-37
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- K-562 cells were subjected to SDS PAGE followed by western blot with 14155-1-AP(FKBP5 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-FKBP5 (IP:14155-1-AP, 3ug; Detection:14155-1-AP 1:1000) with K-562 cells lysate 1500ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 14155-1-AP(FKBP5 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FKBP5 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FKBP5. This antibody recognizes human,mouse,rat antigen. The FKBP5 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
