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- Antibody Data
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- References [4]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- NB100-68240 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-68240, RRID:AB_1108566
- Product name
- Rabbit Polyclonal FKBP51/FKBP5 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references A regulatory role for the co-chaperone FKBP51s in PD-L1 expression in glioma.
Immunomodulatory pathways regulate expression of a spliced FKBP51 isoform in lymphocytes of melanoma patients.
FKBP51 employs both scaffold and isomerase functions to promote NF-κB activation in melanoma.
FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential.
D'Arrigo P, Russo M, Rea A, Tufano M, Guadagno E, Del Basso De Caro ML, Pacelli R, Hausch F, Staibano S, Ilardi G, Parisi S, Romano MF, Romano S
Oncotarget 2017 Sep 15;8(40):68291-68304
Oncotarget 2017 Sep 15;8(40):68291-68304
Immunomodulatory pathways regulate expression of a spliced FKBP51 isoform in lymphocytes of melanoma patients.
Romano S, D'Angelillo A, Staibano S, Simeone E, D'Arrigo P, Ascierto PA, Scalvenzi M, Mascolo M, Ilardi G, Merolla F, Jovarauskaite E, Romano MF
Pigment cell & melanoma research 2015 Jul;28(4):442-52
Pigment cell & melanoma research 2015 Jul;28(4):442-52
FKBP51 employs both scaffold and isomerase functions to promote NF-κB activation in melanoma.
Romano S, Xiao Y, Nakaya M, D'Angelillo A, Chang M, Jin J, Hausch F, Masullo M, Feng X, Romano MF, Sun SC
Nucleic acids research 2015 Aug 18;43(14):6983-93
Nucleic acids research 2015 Aug 18;43(14):6983-93
FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential.
Romano S, Staibano S, Greco A, Brunetti A, Nappo G, Ilardi G, Martinelli R, Sorrentino A, Di Pace A, Mascolo M, Bisogni R, Scalvenzi M, Alfano B, Romano MF
Cell death & disease 2013 Apr 4;4:e578
Cell death & disease 2013 Apr 4;4:e578
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: FKBP51/FKBP5 Antibody [NB100-68240] - Western Blot and Immunoprecipitation: FKBP5/FKBP51 Antibody NB100-68240 - Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 mcg) cells. NB100-68240 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. FKBP5/FKBP51 was also immunoprecipitated by rabbit anti-FKBP5/FKBP51 antibody NB100-68239, which recognizes an upstream epitope.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: FKBP51/FKBP5 Antibody [NB100-68240] - Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-FKBP5/FKBP51 used at a dilution of 1:1,000 (0.2ug/ml). Detection: DAB
