APR00289G

antibody from Leading Biology

Targeting: C3AR1 AZ3B, C3AR

Flow cytometry (Recommended by provider)

Antibody Data

Product number

APR00289G

Provider

Leading Biology

Product name

C3aR Antibody

Antibody type

Polyclonal

Description

C3a is an anaphylatoxin generated thro μgh activation of the complement C3. C3a is a potent chemoattractant for phagocytes, and it stimulates chemotaxis and other leukocyte functions. C3a binds to eosinophils, basophils, neutrophils, and differentiated U937 cells, that all express receptors for C3a on their cell surface. The C3a receptor has been cloned and shown to be a G protein-coupled receptor with seven putative transmembrane domains. This receptor is characterized for its large extracellular loop between the fourth and fifth transmembrane domains. The loop can be readily detected using the rabbit anti-C3a receptor antibody.

Reactivity

Human

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.