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Immunoprecipitation
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 345802 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#345802, RRID:AB_2066747
- Product name
- Purified anti-human C3AR
- Antibody type
- Monoclonal
- Antigen
- hC3aR transfected cells
- Description
- C3AR is a single chain protein of 482 aa, with seven membrane-spanning regions and a molecular weight of 54 Kd. C3AR is expressed by neutrophils, eosinophils, mast cells, monocytes, dendritic cells and there are reports of C3AR expression in non-immune cells such as hematopoietic and mesenchymal stem cells, epithelial and endothelial cells. C3AR is coupled to heterotrimeric G proteins and after C3a binding, the signal transduced, results in chemotaxis, granule enzyme release and superoxide anion production.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4 °C.
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood granulocytes stained with hC3aRZ8 PE
- Conjugate
- Unconjugated
