17-1429-41

antibody from Invitrogen Antibodies
Targeting: F3 CD142, TF
Provider product page for 17-1429-41

Antibody data

Product number
17-1429-41 - Provider product page
Provider
Invitrogen Antibodies
Product name
Anti-CD142 Monoclonal Antibody (HTF-1), APC, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: This HTF-1 monoclonal antibody reacts with human CD142, which is also known as Tissue Factor. Expression of this type I transmembrane glycoprotein on endothelial cells, monocytes, macrophages, and platelets can be induced by inflammatory mediators (e.g., LPS, IL-1b, TNFa, PMA, or endotoxin). On the other hand, CD142 is expressed constitutively by some tumor cells (e.g., lung, pancreatic, breast, and colon) and non-immune tissues such as the vasculature, central nervous system, kidney, epithelia, and placenta. Studies have also suggested that CD142 exists as a soluble form that circulates in blood. CD142 initiates blood coagulation by associating with and activating the circulating factors VII and VIIa. The HTF-1 antibody has been reported to exhibit blocking activity. Applications Reported: This HTF-1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This HTF-1 antibody has been pre-titrated and tested by flow cytometric analysis of LPS-stimulated normal human peripheral blood cells. This can be used at 5 µL (0.06 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 µm post-manufacturing filtered.
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
HTF-1
Vial size
25 Tests
Concentration
5 µL/Test
Storage
4° C, store in dark, DO NOT FREEZE!
F3 protein structure - 17-1429-41 shown in red.