Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Flow cytometry [1]
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Validation data
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- Product number
- ABIN954183 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-phospholipase C beta 2 (PLCb2) (N-Term), (AA 181-210) antibody
- Antibody type
- Polyclonal
- Antigen
- KLH conjugated synthetic peptide between 181~210 amino acids from the N-terminal region of human PLCB2
- Description
- Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- N-Term,AA 181-210
- Vial size
- 0.4 mL
- Concentration
- 0.25 mg/mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Suppression of PLCbeta2 by endotoxin plays a role in the adenosine A(2A) receptor-mediated switch of macrophages from an inflammatory to an angiogenic phenotype.
Tumor suppression by phospholipase C-beta3 via SHP-1-mediated dephosphorylation of Stat5.
Grinberg S, Hasko G, Wu D, Leibovich SJ
The American journal of pathology 2009 Dec;175(6):2439-53
The American journal of pathology 2009 Dec;175(6):2439-53
Tumor suppression by phospholipase C-beta3 via SHP-1-mediated dephosphorylation of Stat5.
Xiao W, Hong H, Kawakami Y, Kato Y, Wu D, Yasudo H, Kimura A, Kubagawa H, Bertoli LF, Davis RS, Chau LA, Madrenas J, Hsia CC, Xenocostas A, Kipps TJ, Hennighausen L, Iwama A, Nakauchi H, Kawakami T
Cancer cell 2009 Aug 4;16(2):161-71
Cancer cell 2009 Aug 4;16(2):161-71
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of PLCB2 Antibody (N-term) Cat.-No AP53334PU-N in K562 cell line lysates (35ug/lane). PLCB2 (arrow) was detected using the purified Pab.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Flow cytometric analysis of k562 cells using PLCB2 Antibody (N-term) Cat.-No AP53334PU-N (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.