ABIN250711

antibody from antibodies-online

Targeting: ERN1 IRE1, IRE1P

Western blot (Supportive data in Antibodypedia)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN250711

Provider

antibodies-online

Product name

anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 700-800) antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

AA 700-800

Vial size

0.1 mL

Storage

Store at -20°C. Avoid freeze-thaw cycles.

Handling

Avoid freeze-thaw cycles

References

Submitted references

Effects of a Sublethal and Transient Stress of the Endoplasmic Reticulum on the Mitochondrial Population.

Vannuvel K, Van Steenbrugge M, Demazy C, Ninane N, Fattaccioli A, Fransolet M, Renard P, Raes M, Arnould T
Journal of cellular physiology 2016 Sep;231(9):1913-31

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Carboxylesterase 2 prevents liver steatosis by modulating lipolysis, endoplasmic reticulum stress, and lipogenesis and is regulated by hepatocyte nuclear factor 4 alpha in mice.

Li Y, Zalzala M, Jadhav K, Xu Y, Kasumov T, Yin L, Zhang Y
Hepatology (Baltimore, Md.) 2016 Jun;63(6):1860-74

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Effect of Cudrania tricuspidata and Kaempferol in Endoplasmic Reticulum Stress-Induced Inflammation and Hepatic Insulin Resistance in HepG2 Cells.

Kim OK, Jun W, Lee J
Nutrients 2016 Jan 21;8(1)

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Requirement of clusterin expression for prosurvival autophagy in hypoxic kidney tubular epithelial cells.

Alnasser HA, Guan Q, Zhang F, Gleave ME, Nguan CY, Du C
American journal of physiology. Renal physiology 2016 Jan 15;310(2):F160-73

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Hyperhomocysteinemia causes ER stress and impaired autophagy that is reversed by Vitamin B supplementation.

Tripathi M, Zhang CW, Singh BK, Sinha RA, Moe KT, DeSilva DA, Yen PM
Cell death & disease 2016 Dec 8;7(12):e2513

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Elevated Endoplasmic Reticulum Stress Response Contributes to Adipose Tissue Inflammation in Aging.

Ghosh AK, Garg SK, Mau T, O'Brien M, Liu J, Yung R
The journals of gerontology. Series A, Biological sciences and medical sciences 2015 Nov;70(11):1320-9

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Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation.

Clarke JR, Lyra E Silva NM, Figueiredo CP, Frozza RL, Ledo JH, Beckman D, Katashima CK, Razolli D, Carvalho BM, Frazão R, Silveira MA, Ribeiro FC, Bomfim TR, Neves FS, Klein WL, Medeiros R, LaFerla FM, Carvalheira JB, Saad MJ, Munoz DP, Velloso LA, Ferreira ST, De Felice FG
EMBO molecular medicine 2015 Feb;7(2):190-210

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Melatonin inhibits tunicamycin-induced endoplasmic reticulum stress and insulin resistance in skeletal muscle cells.

Quan X, Wang J, Liang C, Zheng H, Zhang L
Biochemical and biophysical research communications 2015 Aug 7;463(4):1102-7

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Deficiency of osteoblastic Arl6ip5 impaired osteoblast differentiation and enhanced osteoclastogenesis via disturbance of ER calcium homeostasis and induction of ER stress-mediated apoptosis.

Wu Y, Yang M, Fan J, Peng Y, Deng L, Ding Y, Yang R, Zhou J, Miao D, Fu Q
Cell death & disease 2014 Oct 16;5:e1464

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The resveratrol attenuates ethanol-induced hepatocyte apoptosis via inhibiting ER-related caspase-12 activation and PDE activity in vitro.

Liu LQ, Fan ZQ, Tang YF, Ke ZJ
Alcoholism, clinical and experimental research 2014 Mar;38(3):683-93

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RNF13, a RING finger protein, mediates endoplasmic reticulum stress-induced apoptosis through the inositol-requiring enzyme (IRE1α)/c-Jun NH2-terminal kinase pathway.

Arshad M, Ye Z, Gu X, Wong CK, Liu Y, Li D, Zhou L, Zhang Y, Bay WP, Yu VC, Li P
The Journal of biological chemistry 2013 Mar 22;288(12):8726-36

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Carbon monoxide-releasing molecules reverse leptin resistance induced by endoplasmic reticulum stress.

Zheng M, Zhang Q, Joe Y, Kim SK, Uddin MJ, Rhew H, Kim T, Ryter SW, Chung HT
American journal of physiology. Endocrinology and metabolism 2013 Apr 1;304(7):E780-8

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Anti-apoptotic function of Xbp1 as an IL-3 signaling molecule in hematopoietic cells.

Kurata M, Yamazaki Y, Kanno Y, Ishibashi S, Takahara T, Kitagawa M, Nakamura T
Cell death & disease 2011 Feb 10;2:e118

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AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response.

Luo D, He Y, Zhang H, Yu L, Chen H, Xu Z, Tang S, Urano F, Min W
The Journal of biological chemistry 2008 May 2;283(18):11905-12

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Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1.

Lipson KL, Fonseca SG, Ishigaki S, Nguyen LX, Foss E, Bortell R, Rossini AA, Urano F
Cell metabolism 2006 Sep;4(3):245-54

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WFS1 is a novel component of the unfolded protein response and maintains homeostasis of the endoplasmic reticulum in pancreatic beta-cells.

Fonseca SG, Fukuma M, Lipson KL, Nguyen LX, Allen JR, Oka Y, Urano F
The Journal of biological chemistry 2005 Nov 25;280(47):39609-15

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Fluoride induces endoplasmic reticulum stress in ameloblasts responsible for dental enamel formation.

Kubota K, Lee DH, Tsuchiya M, Young CS, Everett ET, Martinez-Mier EA, Snead ML, Nguyen L, Urano F, Bartlett JD
The Journal of biological chemistry 2005 Jun 17;280(24):23194-202

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Immunohistochemistry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

IHC

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

IHC