Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- ABIN500052 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) antibody
- Antibody type
- Polyclonal
- Antigen
- Human IRE1p (Intermediate Domain) Peptide (ABIN500051)
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store the antibody undiluted at 2-8°C. Shelf life: one year from despatch.
Submitted references The ER chaperone and signaling regulator GRP78/BiP as a monitor of endoplasmic reticulum stress.
ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals.
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response.
The glucose-regulated proteins (GRP78 and GRP94): functions, gene regulation, and applications.
Lee AS
Methods (San Diego, Calif.) 2005 Apr;35(4):373-81
Methods (San Diego, Calif.) 2005 Apr;35(4):373-81
ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals.
Shen J, Chen X, Hendershot L, Prywes R
Developmental cell 2002 Jul;3(1):99-111
Developmental cell 2002 Jul;3(1):99-111
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response.
Bertolotti A, Zhang Y, Hendershot LM, Harding HP, Ron D
Nature cell biology 2000 Jun;2(6):326-32
Nature cell biology 2000 Jun;2(6):326-32
The glucose-regulated proteins (GRP78 and GRP94): functions, gene regulation, and applications.
Little E, Ramakrishnan M, Roy B, Gazit G, Lee AS
Critical reviews in eukaryotic gene expression 1994;4(1):1-18
Critical reviews in eukaryotic gene expression 1994;4(1):1-18
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Supportive validation
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- antibodies-online (provider)
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- Experimental details
- Western blot analysis of IRE1p in Raji cell lysate with AP30446PU-N IRE1p antibody at (A) 1 and (B) 2 ?g/ml.