abx004748

antibody from Abbexa

Targeting: TAP1 ABCB2, D6S114E, PSF1, RING4

Western blot

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Validation data

Product number: abx004748 - Provider product page
Provider: Abbexa
Product name: Antigen Peptide Transporter 1 (TAP1) Antibody
Antibody type: Polyclonal
Description: TAP1 Antibody is a Rabbit Polyclonal antibody against TAP1. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 100 µl
Concentration: > 1 mg/ml
Storage: Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

TAP1 protein structure - abx004748 shown in red.