Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- ELISA [1]
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Validation data
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- Product number
- H00002730-M01 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00002730-M01, RRID:AB_828975
- Product name
- Mouse Monoclonal GCLM Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. GCLM (2B8)
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references ZNF143 transcription factor mediates cell survival through upregulation of the GPX1 activity in the mitochondrial respiratory dysfunction.
Protection against 2-chloroethyl ethyl sulfide (CEES)-induced cytotoxicity in human keratinocytes by an inducer of the glutathione detoxification pathway.
Role of the Nrf2-ARE pathway in acrylamide neurotoxicity.
Molecular and functional characterizations of gastrula organizer cells derived from human embryonic stem cells.
Diversity in antioxidant response enzymes in progressive stages of human nonalcoholic fatty liver disease.
Induction of avian musculoaponeurotic fibrosarcoma proteins by toxic bile acid inhibits expression of glutathione synthetic enzymes and contributes to cholestatic liver injury in mice.
Induction of antioxidant enzymes by curcumin and its analogues in human islets: implications in transplantation.
Lu W, Chen Z, Zhang H, Wang Y, Luo Y, Huang P
Cell death & disease 2012 Nov 15;3:e422
Cell death & disease 2012 Nov 15;3:e422
Protection against 2-chloroethyl ethyl sulfide (CEES)-induced cytotoxicity in human keratinocytes by an inducer of the glutathione detoxification pathway.
Abel EL, Bubel JD, Simper MS, Powell L, McClellan SA, Andreeff M, MacLeod MC, DiGiovanni J
Toxicology and applied pharmacology 2011 Sep 1;255(2):176-83
Toxicology and applied pharmacology 2011 Sep 1;255(2):176-83
Role of the Nrf2-ARE pathway in acrylamide neurotoxicity.
Zhang L, Gavin T, Barber DS, LoPachin RM
Toxicology letters 2011 Aug 10;205(1):1-7
Toxicology letters 2011 Aug 10;205(1):1-7
Molecular and functional characterizations of gastrula organizer cells derived from human embryonic stem cells.
Sharon N, Mor I, Golan-lev T, Fainsod A, Benvenisty N
Stem cells (Dayton, Ohio) 2011 Apr;29(4):600-8
Stem cells (Dayton, Ohio) 2011 Apr;29(4):600-8
Diversity in antioxidant response enzymes in progressive stages of human nonalcoholic fatty liver disease.
Hardwick RN, Fisher CD, Canet MJ, Lake AD, Cherrington NJ
Drug metabolism and disposition: the biological fate of chemicals 2010 Dec;38(12):2293-301
Drug metabolism and disposition: the biological fate of chemicals 2010 Dec;38(12):2293-301
Induction of avian musculoaponeurotic fibrosarcoma proteins by toxic bile acid inhibits expression of glutathione synthetic enzymes and contributes to cholestatic liver injury in mice.
Yang H, Ko K, Xia M, Li TW, Oh P, Li J, Lu SC
Hepatology (Baltimore, Md.) 2010 Apr;51(4):1291-301
Hepatology (Baltimore, Md.) 2010 Apr;51(4):1291-301
Induction of antioxidant enzymes by curcumin and its analogues in human islets: implications in transplantation.
Balamurugan AN, Akhov L, Selvaraj G, Pugazhenthi S
Pancreas 2009 May;38(4):454-60
Pancreas 2009 May;38(4):454-60
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: GCLM Antibody (2B8) [H00002730-M01] - GCLM monoclonal antibody (M01), clone 2B8 Analysis of GCLM expression in HeLa.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Sandwich ELISA: GCLM Antibody (2B8) [H00002730-M01] - Detection limit for recombinant GST tagged GCLM is approximately 1ng/ml as a capture antibody.