GTX16315

antibody from GeneTex

Targeting: GCLC GCS, GLCL, GLCLC

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

GTX16315

Provider

GeneTex

Product name

GCLC antibody, N-term

Antibody type

Polyclonal

Reactivity

Human, Mouse

Host

Rabbit

References

Submitted references

Trans-cinnamic acid attenuates UVA-induced photoaging through inhibition of AP-1 activation and induction of Nrf2-mediated antioxidant genes in human skin fibroblasts.

Hseu YC, Korivi M, Lin FY, Li ML, Lin RW, Wu JJ, Yang HL
Journal of dermatological science 2018 May;90(2):123-134

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Caffeic acid and resveratrol ameliorate cellular damage in cell and Drosophila models of spinocerebellar ataxia type 3 through upregulation of Nrf2 pathway.

Wu YL, Chang JC, Lin WY, Li CC, Hsieh M, Chen HW, Wang TS, Wu WT, Liu CS, Liu KL
Free radical biology & medicine 2018 Feb 1;115:309-317

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Hericium erinaceus Inhibits TNF-α-Induced Angiogenesis and ROS Generation through Suppression of MMP-9/NF-κB Signaling and Activation of Nrf2-Mediated Antioxidant Genes in Human EA.hy926 Endothelial Cells.

Chang HC, Yang HL, Pan JH, Korivi M, Pan JY, Hsieh MC, Chao PM, Huang PJ, Tsai CT, Hseu YC
Oxidative medicine and cellular longevity 2016;2016:8257238

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Caveolin-1 Expression Ameliorates Nephrotic Damage in a Rabbit Model of Cholesterol-Induced Hypercholesterolemia.

Chen YH, Lin WW, Liu CS, Hsu LS, Lin YM, Su SL
PloS one 2016;11(4):e0154210

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Dermato-protective properties of ergothioneine through induction of Nrf2/ARE-mediated antioxidant genes in UVA-irradiated Human keratinocytes.

Hseu YC, Lo HW, Korivi M, Tsai YC, Tang MJ, Yang HL
Free radical biology & medicine 2015 Sep;86:102-17

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M1 Muscarinic Receptor Deficiency Attenuates Azoxymethane-Induced Chronic Liver Injury in Mice.

Rachakonda V, Jadeja RN, Urrunaga NH, Shah N, Ahmad D, Cheng K, Twaddell WS, Raufman JP, Khurana S
Scientific reports 2015 Sep 16;5:14110

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Anti-angiogenic properties of coenzyme Q0 through downregulation of MMP-9/NF-κB and upregulation of HO-1 signaling in TNF-α-activated human endothelial cells.

Yang HL, Korivi M, Lin MW, Chen SC, Chou CW, Hseu YC
Biochemical pharmacology 2015 Nov 1;98(1):144-56

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M1 muscarinic receptors modify oxidative stress response to acetaminophen-induced acute liver injury.

Urrunaga NH, Jadeja RN, Rachakonda V, Ahmad D, McLean LP, Cheng K, Shah V, Twaddell WS, Raufman JP, Khurana S
Free radical biology & medicine 2015 Jan;78:66-81

Western blot

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

WB analysis of human liver lysate using GCLC antibody.

Validation comment

WB

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Human liver lysates were used for Western Blot analysis. The membrane was blotted with anti-GCLC Antibody Titration: 0.2-1 ug/ml. A: - blocking peptide. B: + blocking peptide.

Validation comment

WB