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- Antigen structure
- References [5]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Flow cytometry [1]
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- Product number
- ABIN953526 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) (MSH2) (Center) antibody
- Antibody type
- Polyclonal
- Antigen
- Other
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 0.1 mg
Submitted references Association between genetic polymorphisms in the XRCC1, XRCC3, XPD, GSTM1, GSTT1, MSH2, MLH1, MSH3, and MGMT genes and radiosensitivity in breast cancer patients.
Comprehensive analysis of DNA repair gene polymorphisms and survival in patients with early stage non-small-cell lung cancer.
Risk of urothelial bladder cancer in Lynch syndrome is increased, in particular among MSH2 mutation carriers.
Polymorphisms in ERCC2, MSH2, and OGG1 DNA repair genes and gallbladder cancer risk in a population of Northern India.
Loss of hMSH2 gene expression correlates with improved survival in patients with sporadic colorectal cancer.
Mangoni M, Bisanzi S, Carozzi F, Sani C, Biti G, Livi L, Barletta E, Costantini AS, Gorini G
International journal of radiation oncology, biology, physics 2011 Sep 1;81(1):52-8
International journal of radiation oncology, biology, physics 2011 Sep 1;81(1):52-8
Comprehensive analysis of DNA repair gene polymorphisms and survival in patients with early stage non-small-cell lung cancer.
Kim M, Kang HG, Lee SY, Lee HC, Lee EB, Choi YY, Lee WK, Cho S, Jin G, Jheon HS, Son JW, Lee MH, Jung DK, Cha SI, Kim CH, Kang YM, Kam S, Jung TH, Jheon S, Park JY
Cancer science 2010 Nov;101(11):2436-42
Cancer science 2010 Nov;101(11):2436-42
Risk of urothelial bladder cancer in Lynch syndrome is increased, in particular among MSH2 mutation carriers.
van der Post RS, Kiemeney LA, Ligtenberg MJ, Witjes JA, Hulsbergen-van de Kaa CA, Bodmer D, Schaap L, Kets CM, van Krieken JH, Hoogerbrugge N
Journal of medical genetics 2010 Jul;47(7):464-70
Journal of medical genetics 2010 Jul;47(7):464-70
Polymorphisms in ERCC2, MSH2, and OGG1 DNA repair genes and gallbladder cancer risk in a population of Northern India.
Srivastava K, Srivastava A, Mittal B
Cancer 2010 Jul 1;116(13):3160-9
Cancer 2010 Jul 1;116(13):3160-9
Loss of hMSH2 gene expression correlates with improved survival in patients with sporadic colorectal cancer.
Langner E, Przybylowska K, Trzcinski R, Mik M, Galbfach P, Smolarz B, Romanowicz-Makowska H, Smigileski J, Kulig A, Dziki A
Journal of genetics 2010 Apr;89(1):101-4
Journal of genetics 2010 Apr;89(1):101-4
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis in K562 cell line lysates (35ug/lane) using MSH2 antibody Cat.-No. AP52757PU-N. This demonstrates this antibody detected the MSH2 protein (arrow).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Confocal immunofluorescent analysis with Hela cells using MSH2 antibody Cat.-No. AP52757PU-N, followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram) using MSH2 antibody Cat.-No. AP52757PU-N, followed by FITC-conjugated goat-anti-rabbit secondary antibodies.
