BS5964

antibody from Bioworld Technology, Inc
Targeting: GTF2E2 FE, TF2E2, TFIIE-B
Provider product page for BS5964
Western blot
Immunohistochemistry

Antibody data

Product number
BS5964 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TFIIE ÉÇ polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 193-238 of Human TFIIE-ÉÇ.
Description
In eukaryotic systems, initiation of transcription from protein-coding genes is a complex process requiring RNA polymerase II and broad families of auxiliary transcription factors. Such factors can be divided into two major functional classes: the basal factors that are required for transcription of all Pol II genes, including TFIIA, TFIIB, TFIID, TFIIE, TFIIF and TFIIH; and sequencespecific factors that regulate gene expression. The basal transcription factors and Pol II form a specific multiprotein complex near the transcriptional start site by interacting with core promotor elements such as the TATA box generally located 25-30 base pairs upstream of the transcription start site. Human TFIIE consists of two subunits of 56 kDa and 34 kDa molecular weight, respectively. The structure of TFIIE appears to be a heterotetramer(Ï«2 ÉÇ2) both subunits being required for optimal basal-level transcription .
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
GTF2E2 protein structure - BS5964 shown in red.