BS7731

antibody from Bioworld Technology, Inc
Targeting: DKK1 DKK-1, SK
Provider product page for BS7731
Western blot
Immunohistochemistry

Antibody data

Product number
BS7731 - Provider product page
Provider
Bioworld Technology, Inc
Product name
DKK1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human DKK1.
Description
The Dickkopf family of secreted inhibitors of Wnt signaling ensures proper morphological development by antagonizing different stages of the Wnt cascade. Dkk-1 (Dickkopf-1) acts upstream of b-catenin and dishevelled to inhibit Wnt signaling. Dkk-1 is a 266-amino acid (human), secreted protein that contains a 31-residue N-terminal signal peptide, 2 cysteine rich domains, and a putative carboxy terminal N-glycosylation site. Human Dkk-1 transcripts are abundantly present in fetal kidney, adult placenta and adult prostate. Putative cis regulatory elements upstream of the Dkk-1 start site include p53, Sp1, MyoD, STAT, Oct-1/2, C/EBP-a, C/EBP-b, GATA-1, GATA-2 and GATA-3.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
DKK1 protein structure - BS7731 shown in red.