BS4258

antibody from Bioworld Technology, Inc

Targeting: ADD1

Immunohistochemistry

Antibody data

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Validation data

Product number: BS4258 - Provider product page
Provider: Bioworld Technology, Inc
Product name: Adducin Ï« (phospho T445) polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic phosphopeptide derived from human Adducin Ï« around the phosphorylation site of Threonine 445.
Description: Adducins are a family of cytoskeleton proteins encoded by three genes (Ï«, ÉÇ, ÎÛ). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-actin junction of the membrane skeleton. The cortical actin cytoskeletal network is lost during apoptosis and Adducins are central in the cortical actin network organization. Adducin Ï« is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin Ï« and Adducin ÎÛ is ubiquitous in contrast to the restricted expression of Adducin ÉÇ. Adducin ÉÇ is expressed at high levels in brain and hematopoietic tissues, such as bone marrow, in humans, and in spleen in mice.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

ADD1 protein structure - BS4258 shown in red.