BS5643

CASP14 antibody from Bioworld Technology, Inc
MGC119078, MGC119079, MICE

Antibody data

Product number
BS5643
Provider
Bioworld Technology, Inc
Product name
Caspase 14 p10 polyclonal antibody
Provider product page
Bioworld Technology, Inc - BS5643
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 163-208 of Human Caspase 14.
Description
Caspases are a family of cysteine proteases that play an essential role in carrying out apoptosis. Caspase-14, also named MICE, is a unique member of the caspase family with restricted expression; it is found in embryonic tissues and adult skin. Caspase-14 is weakly processed into p19 and p10 subunits by caspase-8. Caspase-14 may not play a role in apoptosis, but instead may regulate keratinocyte differentiation. Expression of caspase-14 may protect from psoriasis and irradiation damage. Caspase-14 may also be responsible for proteolytic processing of filaggrin during terminal differentiation of keratinocytes.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Provider Type Product Number
- No reagents -