AMM03323G

CASP14 antibody from Leading Biology
MGC119078, MGC119079, MICE
Western blot
Recommended by provider
Immunocytochemistry
Recommended by provider

Antibody data

Product number
AMM03323G
Provider
Leading Biology
Product name
CASP14 Antibody (monoclonal) (M01)
Provider product page
Leading Biology - AMM03323G
Antibody type
Monoclonal
Description
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
4C9
Storage
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Provider Type Product Number
- No reagents -