Antibody data
- Antibody Data
- Antigen structure
- References [459]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11306-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11306-1-AP, RRID:AB_2259061
- Product name
- Beclin 1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Beclin 1 antibody (Cat. #11306-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Corilagin induces apoptosis and inhibits autophagy of HL‑60 cells by regulating miR‑451/HMGB1 axis.
Mettl3 inhibits the apoptosis and autophagy of chondrocytes in inflammation through mediating Bcl2 stability via Ythdf1-mediated m6A modification.
Overexpression of sFlt-1 represses ox-LDL-induced injury of HUVECs by activating autophagy via PI3K/AKT/mTOR pathway.
Inhibition of CDK1 attenuates neuronal apoptosis and autophagy and confers neuroprotection after chronic spinal cord injury in vivo.
Iron overload inhibits cell proliferation and promotes autophagy via PARP1/SIRT1 signaling in endometriosis and adenomyosis.
Screening and identification of NOTCH1, CDKN2A, and NOS3 as differentially expressed autophagy-related genes in erectile dysfunction.
Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS.
A new way for punicalagin to alleviate insulin resistance: regulating gut microbiota and autophagy.
Metformin Inhibits Abdominal Aortic Aneurysm Formation through the Activation of the AMPK/mTOR Signaling Pathway.
Oleanolic Acid Induces Autophagy and Apoptosis via the AMPK-mTOR Signaling Pathway in Colon Cancer.
Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-α Activation.
Apigenin Alleviates Liver Fibrosis by Inhibiting Hepatic Stellate Cell Activation and Autophagy via TGF-β1/Smad3 and p38/PPARα Pathways.
Electroacupuncture Inhibits Autophagy of Neuron Cells in Postherpetic Neuralgia by Increasing the Expression of miR-223-3p.
Pemafibrate Pretreatment Attenuates Apoptosis and Autophagy during Hepatic Ischemia-Reperfusion Injury by Modulating JAK2/STAT3β/PPARα Pathway.
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
PPARγ Plays an Important Role in Acute Hepatic Ischemia-Reperfusion Injury via AMPK/mTOR Pathway.
Imbalance of Autophagy and Apoptosis Induced by Oxidative Stress May Be Involved in Thyroid Damage Caused by Sleep Deprivation in Rats.
Babao Dan Reverses Multiple-Drug Resistance in Gastric Cancer Cells via Triggering Apoptosis and Autophagy and Inhibiting PI3K/AKT/mTOR Signaling.
HIF-1α Activation Promotes Luteolysis by Enhancing ROS Levels in the Corpus Luteum of Pseudopregnant Rats.
Genome-scale CRISPRa screening identifies MTX1 as a contributor for sorafenib resistance in hepatocellular carcinoma by augmenting autophagy.
Vagal Nerve Stimulation Protects Against Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting Autophagy and Apoptosis.
Progranulin Protects Against Airway Remodeling Through the Modulation of Autophagy via HMGB1 Suppression in House Dust Mite-Induced Chronic Asthma.
Bone Autophagy: A Potential Way of Exercise-Mediated Meg3/P62/Runx2 Pathway to Regulate Bone Formation in T2DM Mice.
Combination effect of curcumin with docetaxel on the PI3K/AKT/mTOR pathway to induce autophagy and apoptosis in esophageal squamous cell carcinoma.
p53 Deacetylation Alleviates Sepsis-Induced Acute Kidney Injury by Promoting Autophagy.
Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.
Neuroprotective Effects of Oxymatrine on PI3K/Akt/mTOR Pathway After Hypoxic-Ischemic Brain Damage in Neonatal Rats.
Aiduqing formula suppresses breast cancer metastasis via inhibiting CXCL1-mediated autophagy.
Mitochondrial dysfunction and mitophagy pathway activation in hepatitis E virus-infected livers of Mongolian gerbils.
Lipolysis and lipophagy play individual and interactive roles in regulating triacylglycerol and cholesterol homeostasis and mitochondrial form in zebrafish.
HIV-1 Env induces pexophagy and an oxidative stress leading to uninfected CD4+ T cell death.
Molecular characterization and role in virus infection of Beclin-1 in large yellow croaker (Larimichthys crocea).
Inhibition of DNMT-1 alleviates ferroptosis through NCOA4 mediated ferritinophagy during diabetes myocardial ischemia/reperfusion injury.
WAC, a novel GBM tumor suppressor, induces GBM cell apoptosis and promotes autophagy.
Activation of Autophagy Ameliorates Age-Related Neurogenesis Decline and Neurodysfunction in Adult Mice.
Latcripin-7A from Lentinula edodes C91-3 induces apoptosis, autophagy, and cell cycle arrest at G1 phase in human gastric cancer cells via inhibiting PI3K/Akt/mTOR signaling.
Apelin/APJ signaling activates autophagy to promote human lung adenocarcinoma cell migration.
UPF1 impacts on mTOR signaling pathway and autophagy in endometrioid endometrial carcinoma.
Autophagy was activated against the damages of placentas caused by nano-copper oral exposure.
Circular RNA circMMP1 Contributes to the Progression of Glioma Through Regulating TGIF2 Expression by Sponging miR-195-5p.
Effect and mechanism of action of SLP-2 on the apoptosis and autophagy of gastric cancer cells.
Hsa_circ_0004058 inhibits apoptosis of SRA01/04 cells by promoting autophagy via miR-186/ATG7 axis.
PUF60 of Japanese flounder is regulated by pol-miR-novel_395 and involved in pathogen infection, autophagy, and apoptosis.
The anticancer activity of root extract from Quercus acutissima Carruth. Via regulating apoptosis and autophagy in breast cancer cells.
Transcription factor EB enhances autophagy and ameliorates palmitate-induced insulin resistance at least partly via upregulating AMPK activity in skeletal muscle cells.
Hepatoprotective effects of ginsenoside Rk3 in acetaminophen-induced liver injury in mice by activation of autophagy.
Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy.
Metformin sensitises hepatocarcinoma cells to methotrexate by targeting dihydrofolate reductase.
Co-modification with MSC membrane and PDA prevents Fe3O4-induced pulmonary toxicity in mice via AMPK-ULK1 axis.
Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes the proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathway.
Extracellular IL-37 promotes osteogenic and odontogenic differentiation of human dental pulp stem cells via autophagy.
Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells.
Cycloastragenol alleviates airway inflammation in asthmatic mice by inhibiting autophagy.
Extracellular vesicles originating from autophagy mediate an antibody-resistant spread of classical swine fever virus in cell culture.
2-Amino-3-Methylimidazo[4,5-f]quinoline Triggering Liver Damage by Inhibiting Autophagy and Inducing Endoplasmic Reticulum Stress in Zebrafish (Danio rerio).
Maternal selenium deficiency suppresses proliferation, induces autophagy dysfunction and apoptosis in the placenta of mice.
Exopolysaccharides from Bifidobacterium animalis Ameliorate Escherichia coli-Induced IPEC-J2 Cell Damage via Inhibiting Apoptosis and Restoring Autophagy.
The SGLT2 inhibitor empagliflozin negatively regulates IL-17/IL-23 axis-mediated inflammatory responses in T2DM with NAFLD via the AMPK/mTOR/autophagy pathway.
Luteolin inhibits autophagy in allergic asthma by activating PI3K/Akt/mTOR signaling and inhibiting Beclin-1-PI3KC3 complex.
Comparison of toxicity of Ti3 C2 and Nb2 C Mxene quantum dots (QDs) to human umbilical vein endothelial cells.
Roles of endoplasmic reticulum stress in 2,2',4,4'-tetrabromodiphenylether-induced thyroid cell apoptosis and autophagy.
Chloroquine enhances catalpol's ability to promote apoptosis by inhibiting catalpol's autophagy-promoting effect on gastric cancer.
Radiosensitizing effects of curcumin alone or combined with GLUT1 siRNA on laryngeal carcinoma cells through AMPK pathway-induced autophagy.
miR-338-3p inhibits autophagy in a rat model of allergic rhinitis after PM2.5 exposure through AKT/mTOR signaling by targeting UBE2Q1.
S-nitrosoglutathione reductase maintains mitochondrial homeostasis by promoting clearance of damaged mitochondria in porcine preimplantation embryos.
Effects of photoperiod on morphology and function in testis and epididymis of Cricetulus barabensis.
Silver Nanoparticles Induced Oxidative Stress and Mitochondrial Injuries Mediated Autophagy in HC11 Cells Through Akt/AMPK/mTOR Pathway.
Uhrf1 regulates H3K9me2 modification of mTOR to inhibit the effect of autophagy in myocardial ischemia-reperfusion injury.
Cadmium and molybdenum co-exposure triggers autophagy via CYP450s/ROS pathway in duck renal tubular epithelial cells.
Lead-induced cardiomyocytes apoptosis by inhibiting gap junction intercellular communication via autophagy activation.
BIX-01294, a G9a inhibitor, suppresses cell proliferation by inhibiting autophagic flux in nasopharyngeal carcinoma cells.
Metformin protects cardiomyocytes against oxygen-glucose deprivation injury by promoting autophagic flux through AMPK pathway.
Decreased expression of IDH1 by chronic unpredictable stress suppresses proliferation and accelerates senescence of granulosa cells through ROS activated MAPK signaling pathways.
Hydrogen sulfide alleviates apoptosis and autophagy induced by beryllium sulfate in 16HBE cells.
Protective effect of scorpion venom heat-resistant synthetic peptide against PM2.5-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
Metformin attenuates atherosclerosis and plaque vulnerability by upregulating KLF2-mediated autophagy in apoE-/- mice.
Neferine promotes the apoptosis of HNSCC through the accumulation of p62/SQSTM1 caused by autophagic flux inhibition.
HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance.
The mechanism of 5-aminolevulinic acid photodynamic therapy in promoting endoplasmic reticulum stress in the treatment of HR-HPV-infected HeLa cells.
Hydrogen-Rich Medium Regulates Cr(VI)-Induced ER Stress and Autophagy Signaling in DF-1 Cells.
Hypoxic preconditioning rejuvenates mesenchymal stem cells and enhances neuroprotection following intracerebral hemorrhage via the miR-326-mediated autophagy.
Rev-erbα exacerbates hepatic steatosis in alcoholic liver diseases through regulating autophagy.
S100A8 promotes chemoresistance via augmenting autophagy in B‑cell lymphoma cells.
Induction of autophagy by Beclin-1 in granulosa cells contributes to follicular progesterone elevation in ovarian endometriosis.
Radix Polygalae extract exerts antidepressant effects in behavioral despair mice and chronic restraint stress-induced rats probably by promoting autophagy and inhibiting neuroinflammation.
Resveratrol attenuates cigarette smoke induced endothelial apoptosis by activating Notch1 signaling mediated autophagy.
Ketogenic diet induces autophagy to alleviate bleomycin-induced pulmonary fibrosis in murine models.
The reduction of lipid-sourced energy production caused by ATGL inhibition cannot be compensated by activation of HSL, autophagy, and utilization of other nutrients in fish.
PPARγ/NF-κB and TGF-β1/Smad pathway are involved in the anti-fibrotic effects of levo-tetrahydropalmatine on liver fibrosis.
Overexpression of lncRNA Dancr inhibits apoptosis and enhances autophagy to protect cardiomyocytes from endoplasmic reticulum stress injury via sponging microRNA-6324.
Inhibition of autophagy aggravates molybdenum-induced mitochondrial dysfunction by aggravating oxidative stress in duck renal tubular epithelial cells.
Fe3O4 magnetic nanoparticles ameliorate albumin-induced tubulointerstitial fibrosis by autophagy related to Rab7.
CircCDK8 regulates osteogenic differentiation and apoptosis of PDLSCs by inducing ER stress/autophagy during hypoxia.
Escalating dose-multiple binge methamphetamine treatment elicits neurotoxicity, altering gut microbiota and fecal metabolites in mice.
RabGEF1 functions as an oncogene in U251 glioblastoma cells and is involved in regulating AKT and Erk pathways.
Overexpression of miR-431 attenuates hypoxia/reoxygenation-induced myocardial damage via autophagy-related 3.
SIRT1 attenuates sepsis-induced acute kidney injury via Beclin1 deacetylation-mediated autophagy activation.
QiShenYiQi pill activates autophagy to attenuate reactive myocardial fibrosis via the PI3K/AKT/mTOR pathway.
Vascular endothelial cell-secreted exosomes facilitate osteoarthritis pathogenesis by promoting chondrocyte apoptosis.
The variations of endophilin A2-FoxO3a-autophagy signal in angiotensin II-induced dopaminergic neuron injury mouse model and by biochanin A.
Long-term carbon black inhalation induced the inflammation and autophagy of cerebellum in rats.
MEHP induces pyroptosis and autophagy alternation by cathepsin B activation in INS-1 cells.
HBx induces hepatocellular carcinogenesis through ARRB1-mediated autophagy to drive the G1/S cycle.
miR-142-3p and HMGB1 Are Negatively Regulated in Proliferation, Apoptosis, Migration, and Autophagy of Cartilage Endplate Cells.
PIAS1 alleviates diabetic peripheral neuropathy through SUMOlation of PPAR-γ and miR-124-induced downregulation of EZH2/STAT3.
The unique Akt inhibitor SC66 suppressed AMPK activity and abolished autophagy through the EGFR-p62 pathway.
6-Shogaol from ginger shows anti-tumor effect in cervical carcinoma via PI3K/Akt/mTOR pathway.
Circadian misalignment promotes vascular smooth muscle cell apoptosis via defective autophagy.
W436, a novel SMART derivative, exhibits anti-hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.
Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.
EGCG synergizes the therapeutic effect of irinotecan through enhanced DNA damage in human colorectal cancer cells.
Hsa_circ_0092276 promotes doxorubicin resistance in breast cancer cells by regulating autophagy via miR-348/ATG7 axis.
Synthesis, SAR study, and bioactivity evaluation of a series of Quinoline-Indole-Schiff base derivatives: Compound 10E as a new Nur77 exporter and autophagic death inducer.
Mammalian target of rapamycin signaling pathway is involved in synaptic plasticity of the spinal dorsal horn and neuropathic pain in rats by regulating autophagy.
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility.
LncRNA CCAT1 Upregulates ATG5 to Enhance Autophagy and Promote Gastric Cancer Development by Absorbing miR-140-3p.
Advanced oxidation protein products impair autophagic flux in macrophage by inducing lysosomal dysfunction via activation of PI3K-Akt-mTOR pathway in Crohn's disease.
Sodium valproate increases activity of the sirtuin pathway resulting in beneficial effects for spinocerebellar ataxia-3 in vivo.
Enhancement of TEX264-Mediated ER-Phagy Contributes to the Therapeutic Effect of Glycycoumarin against APA Hepatotoxicity in Mice.
Circular RNA ubiquitin-associated protein 2 enhances autophagy and promotes colorectal cancer progression and metastasis via miR-582-5p/FOXO1 signaling.
Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy.
Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy.
Involvement of Mitophagy in Aluminum Oxide Nanoparticle-Induced Impairment of Learning and Memory in Mice.
Expression of long-chain noncoding RNA GAS5 in osteoarthritis and its effect on apoptosis and autophagy of osteoarthritis chondrocytes.
Hydrogen sulfide ameliorates doxorubicin‑induced myocardial fibrosis in rats via the PI3K/AKT/mTOR pathway.
Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process.
Reduction of Autophagosome Overload Attenuates Neuronal Cell Death After Traumatic Brain Injury.
Pentraxin 3 Promotes Glioblastoma Progression by Negative Regulating Cells Autophagy.
HDAC6 Regulates the Fusion of Autophagosome and Lysosome to Involve in Odontoblast Differentiation.
Dendrobium nobile Lindl. Alkaloids Ameliorate Cognitive Dysfunction in Senescence Accelerated SAMP8 Mice by Decreasing Amyloid-β Aggregation and Enhancing Autophagy Activity.
Dioscin Protects against Aβ1-42 Oligomers-Induced Neurotoxicity via the Function of SIRT3 and Autophagy.
Geniposide Enhances Macrophage Autophagy through Downregulation of TREM2 in Atherosclerosis.
Autophagy Contributes to Host Immunity and Protection against Zika Virus Infection via Type I IFN Signaling.
Protective Role of Coenzyme Q10 in Acute Sepsis-Induced Liver Injury in BALB/c Mice.
Bergenin Attenuates Hepatic Fibrosis by Regulating Autophagy Mediated by the PPAR-γ/TGF-β Pathway.
Autophagy Triggered by Oxidative Stress Appears to Be Mediated by the AKT/mTOR Signaling Pathway in the Liver of Sleep-Deprived Rats.
The Class III PI3K/Beclin-1 Autophagic Pathway Participates in the mmLDL-Induced Upregulation of ETA Receptor in Mouse Mesenteric Arteries.
Alantolactone inhibits cell autophagy and promotes apoptosis via AP2M1 in acute lymphoblastic leukemia.
Deletion of mitochondrial uncoupling protein 2 exacerbates mitophagy and cell apoptosis after cerebral ischemia and reperfusion injury in mice.
Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.
The effect of autophagy and mitochondrial fission on Harderian gland is greater than apoptosis in male hamsters during different photoperiods.
Punicalagin Inhibits Tert-Butyl Hydroperoxide-Induced Apoptosis and Extracellular Matrix Degradation in Chondrocytes by Activating Autophagy and Ameliorates Murine Osteoarthritis.
Baicalin Protects Human OA Chondrocytes Against IL-1β-Induced Apoptosis and ECM Degradation by Activating Autophagy via MiR-766-3p/AIFM1 Axis.
Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway.
The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis.
Metformin Promotes Beclin1-Dependent Autophagy to Inhibit the Progression of Gastric Cancer.
The Effects of Puerarin on Autophagy Through Regulating of the PERK/eIF2α/ATF4 Signaling Pathway Influences Renal Function in Diabetic Nephropathy.
Long Noncoding RNA TUG1 Promotes Autophagy-Associated Paclitaxel Resistance by Sponging miR-29b-3p in Ovarian Cancer Cells.
Chlorin A-mediated photodynamic therapy induced apoptosis in human cholangiocarcinoma cells via impaired autophagy flux.
Isovitexin modulates autophagy in Alzheimer's disease via miR-107 signalling.
Eugenol Attenuates Cerebral Ischemia-Reperfusion Injury by Enhancing Autophagy via AMPK-mTOR-P70S6K Pathway.
Hyperoside Protects Human Umbilical Vein Endothelial Cells Against Anticardiolipin Antibody-Induced Injury by Activating Autophagy.
Staphylococcus aureus Avoids Autophagy Clearance of Bovine Mammary Epithelial Cells by Impairing Lysosomal Function.
Empagliflozin Alleviates Hepatic Steatosis by Activating the AMPK-TET2-Autophagy Pathway in vivo and in vitro.
Cardamonin Reduces Acetaminophen-Induced Acute Liver Injury in Mice via Activating Autophagy and NFE2L2 Signaling.
miR-433 Inhibits Neuronal Growth and Promotes Autophagy in Mouse Hippocampal HT-22 Cell Line.
Morroniside Inhibits H2O2-Induced Podocyte Apoptosis by Down-Regulating NOX4 Expression Controlled by Autophagy In Vitro.
Singapore Grouper Iridovirus (SGIV) Inhibited Autophagy for Efficient Viral Replication.
Liraglutide Ameliorates Erectile Dysfunction via Regulating Oxidative Stress, the RhoA/ROCK Pathway and Autophagy in Diabetes Mellitus.
Inhibition of JNK-Mediated Autophagy Promotes Proscillaridin A- Induced Apoptosis via ROS Generation, Intracellular Ca+2 Oscillation and Inhibiting STAT3 Signaling in Breast Cancer Cells.
LETM1 Knockdown Promotes Autophagy and Apoptosis Through AMP-Activated Protein Kinase Phosphorylation-Mediated Beclin-1/Bcl-2 Complex Dissociation in Hepatocellular Carcinoma.
Disulfiram Chelated With Copper Inhibits the Growth of Gastric Cancer Cells by Modulating Stress Response and Wnt/β-catenin Signaling.
NLRP6 contributes to inflammation and brain injury following intracerebral haemorrhage by activating autophagy.
Neferine induces apoptosis by modulating the ROS‑mediated JNK pathway in esophageal squamous cell carcinoma.
Effect of combination of curcumin and GLUT-1 AS-ODN on radiosensitivity of laryngeal carcinoma through regulating autophagy.
Pretreatment with the ALDH2 activator Alda‑1 protects rat livers from ischemia/reperfusion injury by inducing autophagy.
Mycobacterium tuberculosis infection increases the number of osteoclasts and inhibits osteoclast apoptosis by regulating TNF-α-mediated osteoclast autophagy.
Paecilomyces cicadae-fermented Radix astragali activates podocyte autophagy by attenuating PI3K/AKT/mTOR pathways to protect against diabetic nephropathy in mice.
Knockdown of TXNDC9 induces apoptosis and autophagy in glioma and mediates cell differentiation by p53 activation.
Discoidin Domain Receptors 1 Inhibition Alleviates Osteoarthritis via Enhancing Autophagy.
NOD2/c-Jun NH2-Terminal Kinase Triggers Mycoplasma ovipneumoniae-Induced Macrophage Autophagy.
Zinc oxide nanoparticles effectively regulate autophagic cell death by activating autophagosome formation and interfering with their maturation.
Inhibition of autophagy enhances timosaponin AIII-induced lung cancer cell apoptosis and anti-tumor effect in vitro and in vivo.
Clusterin contributes to hepatitis C virus-related hepatocellular carcinoma by regulating autophagy.
QiShenYiQi pill improves the reparative myocardial fibrosis by regulating autophagy.
Effect of autophagy on irradiation‑induced damage in osteoblast‑like MC3T3‑E1 cells.
STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I.
3-Chloro-1, 2-propanediol inhibits autophagic flux by impairment of lysosomal function in HepG2 cells.
Evaluation of toxicity of halloysite nanotubes and multi-walled carbon nanotubes to endothelial cells in vitro and blood vessels in vivo.
Sphingosine-1-phosphate promotes pulmonary artery smooth muscle cells proliferation by stimulating autophagy-mediated E-cadherin/CDH1 down-regulation.
HIF-1α-Mediated Mitophagy Determines ZnO Nanoparticle-Induced Human Osteosarcoma Cell Death both In Vitro and In Vivo.
Phosphatase and Tensin Homolog (PTEN) of Japanese Flounder-Its Regulation by miRNA and Role in Autophagy, Apoptosis and Pathogen Infection.
Design, synthesis, and biological evaluation of 5-((8-methoxy-2-methylquinolin-4-yl)amino)-1H-indole-2-carbohydrazide derivatives as novel Nur77 modulators.
N‑linoleyltyrosine protects PC12 cells against oxidative damage via autophagy: Possible involvement of CB1 receptor regulation.
Drp1-mediated mitochondrial fission induced autophagy attenuates cell apoptosis caused by 3-chlorpropane-1,2-diol in HEK293 cells.
Deficiency of microglial Hv1 channel is associated with activation of autophagic pathway and ROS production in LPC-induced demyelination mouse model.
Sesn2 attenuates the damage of endothelial progenitor cells induced by angiotensin II through regulating the Keap1/Nrf2 signal pathway.
Ganoderic acid D induces synergistic autophagic cell death except for apoptosis in ESCC cells.
Targeted inhibition of GRP78 by HA15 promotes apoptosis of lung cancer cells accompanied by ER stress and autophagy.
Acupuncture protects against cerebral ischemia-reperfusion injury via suppressing endoplasmic reticulum stress-mediated autophagy and apoptosis.
TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis.
Astragaloside IV enhances GATA-4 mediated myocardial protection effect in hypoxia/reoxygenation injured H9c2 cells.
miR-384-5p promotes spinal cord injury recovery in rats through suppressing of autophagy and endoplasmic reticulum stress.
Inhibiting PKCβ2 protects HK-2 cells against meglumine diatrizoate and AGEs-induced apoptosis and autophagy.
A20 inhibits osteoclastogenesis via TRAF6-dependent autophagy in human periodontal ligament cells under hypoxia.
MiRNA-211 triggers an autophagy-dependent apoptosis in cervical cancer cells: regulation of Bcl-2.
CCN1 triggers adaptive autophagy in cardiomyocytes to curb its apoptotic activities.
Mainstream cigarette smoke induces autophagy and promotes apoptosis in oral mucosal epithelial cells.
Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide.
Trehalose reduces bone loss in experimental biliary cirrhosis rats via ERK phosphorylation regulation by enhancing autophagosome formation.
Arsenic induces dysfunctional autophagy via dual regulation of mTOR pathway and Beclin1-Vps34/PI3K complex in MLTC-1 cells.
The RBP1-CKAP4 axis activates oncogenic autophagy and promotes cancer progression in oral squamous cell carcinoma.
Cafestol preconditioning attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting ERK/PPARγ pathway.
The Effect of Autophagic Activity on the Function of Apheresis Platelets and on the Efficacy of Clinical Platelet Transfusion.
GL-V9 reverses adriamycin resistance in hepatocellular carcinoma cells by affecting JNK2-related autophagy.
Tetrahydroxy stilbene glycoside alleviated inflammatory damage by mitophagy via AMPK related PINK1/Parkin signaling pathway.
LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes.
PRDX2 removal inhibits the cell cycle and autophagy in colorectal cancer cells.
Melatonin alleviates defects induced by zearalenone during porcine embryo development.
14-3-3ζ binds to and stabilizes phospho-beclin 1S295 and induces autophagy in hepatocellular carcinoma cells.
Targeting the WEE1 kinase strengthens the antitumor activity of imatinib via promoting KIT autophagic degradation in gastrointestinal stromal tumors.
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
The Preparation of Ginsenoside Rg5, Its Antitumor Activity against Breast Cancer Cells and Its Targeting of PI3K.
NLRP3 inflammasome negatively regulates podocyte autophagy in diabetic nephropathy.
Activation of cannabinoid receptor type 2-induced osteogenic differentiation involves autophagy induction and p62-mediated Nrf2 deactivation.
Autophagy Promotes Duck Tembusu Virus Replication by Suppressing p62/SQSTM1-Mediated Innate Immune Responses In Vitro.
Regular Aerobic Exercise-Alleviated Dysregulation of CAMKIIα Carbonylation to Mitigate Parkinsonism via Homeostasis of Apoptosis With Autophagy.
MCP-1 mediates ischemia-reperfusion-induced cardiomyocyte apoptosis via MCPIP1 and CaSR.
Ginsenoside Rb1 Alleviates Oxidative Low-Density Lipoprotein-Induced Vascular Endothelium Senescence via the SIRT1/Beclin-1/Autophagy Axis.
CB2R orchestrates neuronal autophagy through regulation of the mTOR signaling pathway in the hippocampus of developing rats with status epilepticus.
Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea.
1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway.
High mobility group box 1 antibody represses autophagy and alleviates hippocampus damage in pilocarpine-induced mouse epilepsy model.
MiRNA-192-5p attenuates airway remodeling and autophagy in asthma by targeting MMP-16 and ATG7.
Japanese flounder pol-miR-3p-2 suppresses Edwardsiella tarda infection by regulation of autophagy via p53.
Treadmill exercise improves neurological function by inhibiting autophagy and the binding of HMGB1 to Beclin1 in MCAO juvenile rats.
Protective effect of hydrogen sulfide on endothelial cells through Sirt1-FoxO1-mediated autophagy.
Simvastatin protects high glucose-induced H9c2 cells from injury by inducing autophagy.
Exogenous CGRP Regulates Apoptosis and Autophagy to Alleviate Traumatic Brain Injury Through Akt/mTOR Signalling Pathway.
Disruption of the Keap1/Nrf2-Antioxidant Response System After Chronic Doxorubicin Exposure In Vivo.
Pseudolaric acid B induces apoptosis in human rhabdomyosarcoma RD cells.
Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction.
Intra-Articular Injection of (-)-Epigallocatechin 3-Gallate to Attenuate Articular Cartilage Degeneration by Enhancing Autophagy in a Post-Traumatic Osteoarthritis Rat Model.
Regulation of FN1 degradation by the p62/SQSTM1-dependent autophagy-lysosome pathway in HNSCC.
Inhibition of autophagy enhances cadmium-induced apoptosis in duck renal tubular epithelial cells.
Combined toxic effects of CBNPs and Pb on rat alveolar macrophage apoptosis and autophagy flux.
The protective effects of pretreatment with resveratrol in cyclophosphamide-induced rat ovarian granulosa cell injury: In vitro study.
S100A8 transported by SEC23A inhibits metastatic colonization via autocrine activation of autophagy.
Butyrate-mediated autophagy inhibition limits cytosolic Salmonella Infantis replication in the colon of pigs treated with a mixture of Lactobacillus and Bacillus.
RND2 attenuates apoptosis and autophagy in glioblastoma cells by targeting the p38 MAPK signalling pathway.
Suppressing endoplasmic reticulum stress-related autophagy attenuates retinal light injury.
N6-(2-hydroxyethyl)-Adenosine Induces Apoptosis via ER Stress and Autophagy of Gastric Carcinoma Cells In Vitro and In Vivo.
Protective Effect of Purple Tomato Anthocyanidin on Chromium(VI)-Induced Autophagy in LMH Cells by Inhibiting Endoplasmic Reticulum Stress.
Hydroxysafflor yellow A induces autophagy in human liver cancer cells by regulating Beclin 1 and ERK expression.
Exogenous H2S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice.
Exosomes derived from mesenchymal stem cells repair a Parkinson's disease model by inducing autophagy.
CACNA1H downregulation induces skeletal muscle atrophy involving endoplasmic reticulum stress activation and autophagy flux blockade.
Critical role of Tim-3 mediated autophagy in chronic stress induced immunosuppression.
Isorhamnetin Inhibits Liver Fibrosis by Reducing Autophagy and Inhibiting Extracellular Matrix Formation via the TGF-β1/Smad3 and TGF-β1/p38 MAPK Pathways.
Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy.
Enhanced p62-NRF2 Feedback Loop due to Impaired Autophagic Flux Contributes to Arsenic-Induced Malignant Transformation of Human Keratinocytes.
Gambogic acid induces autophagy and combines synergistically with chloroquine to suppress pancreatic cancer by increasing the accumulation of reactive oxygen species.
FePt/GO Nanosheets Suppress Proliferation, Enhance Radiosensitization and Induce Autophagy of Human Non-Small Cell Lung Cancer Cells.
The ginsenoside Rk3 exerts anti-esophageal cancer activity in vitro and in vivo by mediating apoptosis and autophagy through regulation of the PI3K/Akt/mTOR pathway.
LAPTM4B knockdown increases the radiosensitivity of EGFR-overexpressing radioresistant nasopharyngeal cancer cells by inhibiting autophagy.
Glycyrrhizic acid ameliorates LPS-induced acute lung injury by regulating autophagy through the PI3K/AKT/mTOR pathway.
Diosbulbin B-Induced Mitochondria-Dependent Apoptosis in L-02 Hepatocytes is Regulated by Reactive Oxygen Species-Mediated Autophagy.
The Anti-proliferative Activity of GnRH Through Downregulation of the Akt/ERK Pathways in Pancreatic Cancer.
IL-17A-Mediated Excessive Autophagy Aggravated Neuronal Ischemic Injuries via Src-PP2B-mTOR Pathway.
Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux.
The balance of apoptosis and autophagy via regulation of the AMPK signal pathway in aging rat striatum during regular aerobic exercise.
Corticosterone Excess-Mediated Mitochondrial Damage Induces Hippocampal Neuronal Autophagy in Mice Following Cold Exposure.
Hippocampus Metabolic Disturbance and Autophagy Deficiency in Olfactory Bulbectomized Rats and the Modulatory Effect of Fluoxetine.
PGC-1α acts as an mediator of Sirtuin2 to protect annulus fibrosus from apoptosis induced by oxidative stress through restraining mitophagy.
Orientin Improves Cognition by Enhancing Autophagosome Clearance in an Alzheimer's Mouse Model.
Chrysophanol attenuates airway inflammation and remodeling through nuclear factor-kappa B signaling pathway in asthma.
Inhibited autophagy impairs systemic nutrient metabolism in Nile tilapia.
Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer.
Neuroprotective effect of Verbascoside on hypoxic-ischemic brain damage in neonatal rat.
Quetiapine induces myocardial necroptotic cell death through bidirectional regulation of cannabinoid receptors.
The roles of Nrf2 and autophagy in modulating inflammation mediated by TLR4 - NFκB in A549 cell exposed to layer house particulate matter 2.5 (PM2.5).
Iron dysregulation in vascular dementia: Focused on the AMPK/autophagy pathway.
Emodin reactivated autophagy and alleviated inflammatory lung injury in mice with lethal endotoxemia.
Downregulation of microRNA-30a-5p contributes to the replication of duck enteritis virus by regulating Beclin-1-mediated autophagy.
Beclin1-mediated ferroptosis activation is associated with isoflurane-induced toxicity in SH-SY5Y neuroblastoma cells.
Mitochondrial NDUFA4L2 attenuates the apoptosis of nucleus pulposus cells induced by oxidative stress via the inhibition of mitophagy.
A novel ALK inhibitor ZYY inhibits Karpas299 cell growth in vitro and in a mouse xenograft model and induces protective autophagy.
Punicalagin Prevents Inflammation in LPS-Induced RAW264.7 Macrophages by Inhibiting FoxO3a/Autophagy Signaling Pathway.
Protective effects of levo-tetrahydropalmatine on hepatic ischemia/reperfusion injury are mediated by inhibition of the ERK/NF-κB pathway.
α-hederin induces autophagic cell death in colorectal cancer cells through reactive oxygen species dependent AMPK/mTOR signaling pathway activation.
Paclitaxel alleviates monocrotaline-induced pulmonary arterial hypertension via inhibition of FoxO1-mediated autophagy.
Kallikrein 12 Regulates Innate Resistance of Murine Macrophages against Mycobacterium bovis Infection by Modulating Autophagy and Apoptosis.
The Glycoprotein and Nucleocapsid Protein of Hantaviruses Manipulate Autophagy Flux to Restrain Host Innate Immune Responses.
The preoperative neutrophil-to-lymphocyte ratio is not a marker of prostate cancer characteristics but is an independent predictor of biochemical recurrence in patients receiving radical prostatectomy.
Fasting enhances cold resistance in fish through stimulating lipid catabolism and autophagy.
Pb disrupts autophagic flux through inhibiting the formation and activity of lysosomes in neural cells.
Fibroblast growth factor-21 alleviates hypoxia/reoxygenation injury in H9c2 cardiomyocytes by promoting autophagic flux.
CERKL regulates autophagy via the NAD-dependent deacetylase SIRT1.
Osteosarcoma cell intrinsic PD-L2 signals promote invasion and metastasis via the RhoA-ROCK-LIMK2 and autophagy pathways.
TLR2 promotes development and progression of human glioma via enhancing autophagy.
The long non-coding RNA H19 induces hypoxia/reoxygenation injury by up-regulating autophagy in the hepatoma carcinoma cells.
Mitochondrial dynamics modulation as a critical contribution for Shenmai injection in attenuating hypoxia/reoxygenation injury.
Nonstructural Protein NP1 of Human Bocavirus 1 suppresses the growth of A549 cell by promoting autophagy.
Bone marrow mesenchymal stem cells repair Cr (VI)- injured kidney by regulating mitochondria-mediated apoptosis and mitophagy mediated via the MAPK signaling pathway.
iRoot BP Plus promotes osteo/odontogenic differentiation of bone marrow mesenchymal stem cells via MAPK pathways and autophagy.
Polyethers isolated from the marine actinobacterium Streptomyces cacaoi inhibit autophagy and induce apoptosis in cancer cells.
Berberine ameliorates oxidative stress-induced apoptosis by modulating ER stress and autophagy in human nucleus pulposus cells.
Alleviation of hepatic fibrosis and autophagy via inhibition of transforming growth factor-β1/Smads pathway through shikonin.
The interaction of Atg4B and Bcl-2 plays an important role in Cd-induced crosstalk between apoptosis and autophagy through disassociation of Bcl-2-Beclin1 in A549 cells.
Autophagy and Apoptosis Interact to Modulate T-2 Toxin-Induced Toxicity in Liver Cells.
Down-regulation of lncRNA OGFRP1 induces autophagy and growth inhibition by AKT/mTOR signaling pathway in HCAECs.
α‑lipoic acid protects against carbon tetrachloride‑induced liver cirrhosis through the suppression of the TGF‑β/Smad3 pathway and autophagy.
Effects of Fluoride on Autophagy in Mouse Sertoli Cells.
Microglia as modulators of exosomal alpha-synuclein transmission.
Sodium fluoride regulates the osteo/odontogenic differentiation of stem cells from apical papilla by modulating autophagy.
Icariin Ameliorates Amyloid Pathologies by Maintaining Homeostasis of Autophagic Systems in Aβ1-42-Injected Rats.
Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats.
Punicalagin Reversed the Hepatic Injury of Tetrachloromethane by Antioxidation and Enhancement of Autophagy.
Sufentanil impairs autophagic degradation and inhibits cell migration in NCI-H460 in vitro.
Autophagy Attenuation Hampers Progesterone Synthesis during the Development of Pregnant Corpus Luteum.
PD-L1 regulates tumorigenesis and autophagy of ovarian cancer by activating mTORC signaling.
Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis.
HMGB1/TLR4 promotes apoptosis and reduces autophagy of hippocampal neurons in diabetes combined with OSA.
A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice.
Visfatin Plays a Significant Role in Alleviating Lipopolysaccharide-Induced Apoptosis and Autophagy Through PI3K/AKT Signaling Pathway During Acute Lung Injury in Mice.
Nix/BNIP3L-dependent mitophagy accounts for airway epithelial cell injury induced by cigarette smoke.
Platelet-Membrane-Camouflaged Black Phosphorus Quantum Dots Enhance Anticancer Effect Mediated by Apoptosis and Autophagy.
Role of Thymoquinone in Cardiac Damage Caused by Sepsis from BALB/c Mice.
Autophagy induction and antiproliferative effect of a novel curcumin derivative MOMI-1 on the human lung cancer cells A549.
Potent effects of dioscin against hepatocellular carcinoma through regulating TP53-induced glycolysis and apoptosis regulator (TIGAR)-mediated apoptosis, autophagy, and DNA damage.
Neuroprotective effects of rapamycin on spinal cord injury in rats by increasing autophagy and Akt signaling.
Silver nanoparticles induce protective autophagy via Ca2+/CaMKKβ/AMPK/mTOR pathway in SH-SY5Y cells and rat brains.
Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy.
Evaluating expression of autophagy-related genes in oriental river prawn Macrobrachium nipponense as potential biomarkers for hypoxia exposure.
Autophagy exerts pivotal roles in regulatory effects of 1α,25-(OH)2D3 on the osteoclastogenesis.
Lysophosphatidic Acid Is Associated With Cardiac Dysfunction and Hypertrophy by Suppressing Autophagy via the LPA3/AKT/mTOR Pathway.
The Protective Effects of Levo-Tetrahydropalmatine on ConA-Induced Liver Injury Are via TRAF6/JNK Signaling.
The Hepatoprotection by Oleanolic Acid Preconditioning: Focusing on PPARα Activation.
Fucosterol Protects against Concanavalin A-Induced Acute Liver Injury: Focus on P38 MAPK/NF-κB Pathway Activity.
Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke.
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.
TRIM59 regulates autophagy through modulating both the transcription and the ubiquitination of BECN1.
Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways.
Apolipoprotein E-Mimetic Peptide COG1410 Promotes Autophagy by Phosphorylating GSK-3β in Early Brain Injury Following Experimental Subarachnoid Hemorrhage.
Melatonin Regulates Apoptosis and Autophagy Via ROS-MST1 Pathway in Subarachnoid Hemorrhage.
High expression of TFEB is associated with aggressive clinical features in colorectal cancer.
Human tissue kallikrein 1 ameliorates erectile function via modulation of macroautophagy in aged transgenic rats.
Rapamycin Supplementation May Ameliorate Erectile Function in Rats With Streptozotocin-Induced Type 1 Diabetes by Inducing Autophagy and Inhibiting Apoptosis, Endothelial Dysfunction, and Corporal Fibrosis.
LP1 from Lentinula edodes C91-3 Induces Autophagy, Apoptosis and Reduces Metastasis in Human Gastric Cancer Cell Line SGC-7901.
Moderate hypothermia inhibits microglial activation after traumatic brain injury by modulating autophagy/apoptosis and the MyD88-dependent TLR4 signaling pathway.
The toxic effect of aflatoxin B1 on early porcine embryonic development.
Autophagy is involved in acetylshikonin ameliorating non-alcoholic steatohepatitis through AMPK/mTOR pathway.
Activation of AMPK prevents monocrotaline-induced pulmonary arterial hypertension by suppression of NF-κB-mediated autophagy activation.
Role of autophagy in regulating the immune response of dendritic cells to Talaromyces marneffei infection.
mTORC1-Regulated and HUWE1-Mediated WIPI2 Degradation Controls Autophagy Flux.
Fluoride induces apoptosis and autophagy through the IL-17 signaling pathway in mice hepatocytes.
Excessive apoptosis and disordered autophagy flux contribute to the neurotoxicity induced by high iodine in Sprague-Dawley rat.
Protective effects of α‑2‑macroglobulin on human bone marrow mesenchymal stem cells in radiation injury.
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
Cantharidin suppresses cell growth and migration, and activates autophagy in human non-small cell lung cancer cells.
7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway.
Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury.
Retigabine ameliorates acute stress-induced impairment of spatial memory retrieval through regulating USP2 signaling pathways in hippocampal CA1 area.
Oxidative stress-mediated autophagic cell death participates in the neurotoxic effect on SH-SY5Y cells induced by excessive iodide.
The RNA binding protein tristetraprolin down-regulates autophagy in lung adenocarcinoma cells.
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Autophagy inhibition attenuates the induction of anti-inflammatory effect of catalpol in liver fibrosis.
Autophagy defects and related genetic variations in renal cell carcinoma with eosinophilic cytoplasmic inclusions.
TLR3 contributes to persistent autophagy and heart failure in mice after myocardial infarction.
Pseudolaric acid B induced autophagy, but not apoptosis, in MRC5 human fibroblast cells.
Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy.
Excessive ER stress and the resulting autophagic flux dysfunction contribute to fluoride-induced neurotoxicity.
The Role of SIRT1 in Autophagy in Lipopolysaccharide-Induced Mouse Type II Alveolar Epithelial Cells.
Lycium barbarum polysaccharide attenuates diabetic testicular dysfunction via inhibition of the PI3K/Akt pathway-mediated abnormal autophagy in male mice.
Modulation of autophagy in the protective effect of resveratrol on PM2.5-induced pulmonary oxidative injury in mice.
Tumor cell-released autophagosomes (TRAPs) promote immunosuppression through induction of M2-like macrophages with increased expression of PD-L1.
Trimetazidine protects against myocardial ischemia/reperfusion injury by inhibiting excessive autophagy.
Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells.
Subthalamic nucleus deep brain stimulation protects neurons by activating autophagy via PP2A inactivation in a rat model of Parkinson's disease.
Hispidulin alleviates high-glucose-induced podocyte injury by regulating protective autophagy.
The gastric mucosal protective effects of astragaloside IV in mnng-induced GPL rats.
Autophagy is required for proper meiosis of porcine oocytes maturing in vitro.
Lycium barbarum polysaccharide protects diabetic peripheral neuropathy by enhancing autophagy via mTOR/p70S6K inhibition in Streptozotocin-induced diabetic rats.
Traditional Chinese Medicine CFF-1 induced cell growth inhibition, autophagy, and apoptosis via inhibiting EGFR-related pathways in prostate cancer.
Increased autophagy in EOC re-ascites cells can inhibit cell death and promote drug resistance.
Assessment of Posttranslational Modifications of ATG proteins.
Hydrogen Gas Attenuates Myocardial Ischemia Reperfusion Injury Independent of Postconditioning in Rats by Attenuating Endoplasmic Reticulum Stress-Induced Autophagy.
Ox-LDL-Induced MicroRNA-155 Promotes Autophagy in Human Endothelial Cells via Repressing the Rheb/ mTOR Pathway.
Quercetin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy by Inhibiting ERK/NF-κB Pathway.
HSPB8 Promotes the Fusion of Autophagosome and Lysosome during Autophagy in Diabetic Neurons.
Salidroside pretreatment attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting the mitogen-activated protein kinase pathway in mice.
Combination of Endothelial-Monocyte-Activating Polypeptide-II with Temozolomide Suppress Malignant Biological Behaviors of Human Glioblastoma Stem Cells via miR-590-3p/MACC1 Inhibiting PI3K/AKT/mTOR Signal Pathway.
Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis.
Hyperlipidemia impairs erectile function in rats by causing cavernosal fibrosis.
Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.
VPS34 Acetylation Controls Its Lipid Kinase Activity and the Initiation of Canonical and Non-canonical Autophagy.
Pretreatment with propylene glycol alginate sodium sulfate ameliorated concanavalin A-induced liver injury by regulating the PI3K/Akt pathway in mice.
The natural product fucoidan ameliorates hepatic ischemia-reperfusion injury in mice.
Role of autophagy in cadmium-induced testicular injury.
Circular RNA HIPK2 regulates astrocyte activation via cooperation of autophagy and ER stress by targeting MIR124-2HG.
The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma.
Fluoride-Induced Autophagy via the Regulation of Phosphorylation of Mammalian Targets of Rapamycin in Mice Leydig Cells.
PD149163 induces hypothermia to protect against brain injury in acute cerebral ischemic rats.
The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity.
Anti-osteoclastogenesis of Mineral Trioxide Aggregate through Inhibition of the Autophagic Pathway.
15-Deoxy-Δ12,14-prostaglandin J2 alleviates hepatic ischemia-reperfusion injury in mice via inducing antioxidant response and inhibiting apoptosis and autophagy.
FGF2/FGFR1 regulates autophagy in FGFR1-amplified non-small cell lung cancer cells.
Defective autophagy is associated with neuronal injury in a mouse model of multiple sclerosis.
Cucurbitacin B induces autophagy and apoptosis by suppressing CIP2A/PP2A/mTORC1 signaling axis in human cisplatin resistant gastric cancer cells.
7-O-geranylquercetin-induced autophagy contributes to apoptosis via ROS generation in human non-small cell lung cancer cells.
Propylene Glycol Alginate Sodium Sulfate Alleviates Cerulein-Induced Acute Pancreatitis by Modulating the MEK/ERK Pathway in Mice.
Hydrogen Sulphide modulating mitochondrial morphology to promote mitophagy in endothelial cells under high-glucose and high-palmitate.
Effects of dimethyl carbonate-induced autophagic activation on follicular development in the mouse ovary.
3-Methyladenine ameliorates liver fibrosis through autophagy regulated by the NF-κB signaling pathways on hepatic stellate cell.
Calpain Inhibition Is Protective in Machado-Joseph Disease Zebrafish Due to Induction of Autophagy.
Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways.
Exogenous H2S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy.
Pre-incubation with hucMSC-exosomes prevents cisplatin-induced nephrotoxicity by activating autophagy.
Sensitization of tamoxifen-resistant breast cancer cells by Z-ligustilide through inhibiting autophagy and accumulating DNA damages.
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway-mediated inhibition of extracellular matrix and autophagy.
Novel recombinant protein FlaA N/C increases tumor radiosensitivity via NF-κB signaling in murine breast cancer cells.
Aliskiren targets multiple systems to alleviate cancer cachexia.
Cytoprotective effect of autophagy on phagocytosis of apoptotic cells by macrophages.
Inhibition of AMP-activated protein kinase alleviates focal cerebral ischemia injury in mice: Interference with mTOR and autophagy.
15d-PGJ2 alleviates ConA-induced acute liver injury in mice by up-regulating HO-1 and reducing hepatic cell autophagy.
Excessive apoptosis and defective autophagy contribute to developmental testicular toxicity induced by fluoride.
Pseudolaric acid B activates autophagy in MCF-7 human breast cancer cells to prevent cell death.
Synergistic chemopreventive effects of curcumin and berberine on human breast cancer cells through induction of apoptosis and autophagic cell death.
Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways.
Preventive Effects of a Novel Polysaccharide from Sepia esculenta Ink on Ovarian Failure and Its Action Mechanisms in Cyclophosphamide-Treated Mice.
Effects of Atrazine and Chlorpyrifos on Autophagy-Related Genes in the Brain of Common Carp: Health-Risk Assessments.
Effects of Placental Ischemia Are Attenuated by 1,25-Dihydroxyvitamin D Treatment and Associated with Reduced Apoptosis and Increased Autophagy.
Overexpression of RBM5 induces autophagy in human lung adenocarcinoma cells.
Fentanyl induces autophagy via activation of the ROS/MAPK pathway and reduces the sensitivity of cisplatin in lung cancer cells.
Decreased Level of Klotho Contributes to Drug Resistance in Lung Cancer Cells: Involving in Klotho-Mediated Cell Autophagy.
Dimethyl α-ketoglutarate reduces CCl4-induced liver fibrosis through inhibition of autophagy in hepatic stellate cells.
Anti-osteoclastogenic activity of isoliquiritigenin via inhibition of NF-κB-dependent autophagic pathway.
Low doses of single or combined agrichemicals induces α-synuclein aggregation in nigrostriatal system of mice through inhibition of proteasomal and autophagic pathways.
Inhibition of Notch Signaling Promotes the Adipogenic Differentiation of Mesenchymal Stem Cells Through Autophagy Activation and PTEN-PI3K/AKT/mTOR Pathway.
GBA deficiency promotes SNCA/α-synuclein accumulation through autophagic inhibition by inactivated PPP2A.
Inhibition of autophagy by 3-MA enhances IL-24-induced apoptosis in human oral squamous cell carcinoma cells.
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
Pseudolaric acid B inhibits proliferation in SW579 human thyroid squamous cell carcinoma.
Astaxanthin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy via the ROS/MAPK Pathway in Mice.
Autophagy in SDF-1α-mediated DPSC migration and pulp regeneration.
Suppression of murine experimental autoimmune encephalomyelitis development by 1,25-dihydroxyvitamin D3 with autophagy modulation.
Ischemic postconditioning regulates cardiomyocyte autophagic activity following ischemia/reperfusion injury.
Potent effects of dioscin against obesity in mice.
Suppression of autophagy augments the radiosensitizing effects of STAT3 inhibition on human glioma cells.
Tonsil-derived mesenchymal stem cells ameliorate CCl4-induced liver fibrosis in mice via autophagy activation.
SZC017, a novel oleanolic acid derivative, induces apoptosis and autophagy in human breast cancer cells.
Chemoresistance is associated with Beclin-1 and PTEN expression in epithelial ovarian cancers.
Autophagy is involved in the cardioprotection effect of remote limb ischemic postconditioning on myocardial ischemia/reperfusion injury in normal mice, but not diabetic mice.
Over-expression of Beclin-1 facilitates acquired resistance to histone deacetylase inhibitor-induced apoptosis.
Bone marrow mesenchymal stem cells repair spinal cord ischemia/reperfusion injury by promoting axonal growth and anti-autophagy.
Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis.
Molecular characterization and expression analysis of the autophagic gene beclin 1 from the purse red common carp (Cyprinus carpio) exposed to cadmium.
Ubiquitin‑specific protease 22‑induced autophagy is correlated with poor prognosis of pancreatic cancer.
Dissection of autophagy in human platelets.
Role of membrane association and Atg14-dependent phosphorylation in beclin-1-mediated autophagy.
Cathepsin L stimulates autophagy and inhibits apoptosis of ox-LDL-induced endothelial cells: potential role in atherosclerosis.
Autophagy in endothelial progenitor cells is cytoprotective in hypoxic conditions.
Depletion of Bmi-1 enhances 5-fluorouracil-induced apoptosis and autophagy in hepatocellular carcinoma cells.
DJ-1 protects dopaminergic neurons against rotenone-induced apoptosis by enhancing ERK-dependent mitophagy.
Role of autophagy in monokine induced by interferon γ (Mig) production during adenovirus-hepatitis B virus infection.
Loss of PINK1 function decreases PP2A activity and promotes autophagy in dopaminergic cells and a murine model.
Silencing of PINK1 induces mitophagy via mitochondrial permeability transition in dopaminergic MN9D cells.
Jia S, He D, Liang X, Cheng P, Liu J, Chen M, Wang C, Zhang H, Meng C
Molecular medicine reports 2022 Jan;25(1)
Molecular medicine reports 2022 Jan;25(1)
Mettl3 inhibits the apoptosis and autophagy of chondrocytes in inflammation through mediating Bcl2 stability via Ythdf1-mediated m6A modification.
He Y, Wang W, Xu X, Yang B, Yu X, Wu Y, Wang J
Bone 2022 Jan;154:116182
Bone 2022 Jan;154:116182
Overexpression of sFlt-1 represses ox-LDL-induced injury of HUVECs by activating autophagy via PI3K/AKT/mTOR pathway.
Zhou YH, Tang YZ, Guo LY, Zheng LL, Zhang D, Yang CY, Wang W
Microvascular research 2022 Jan;139:104252
Microvascular research 2022 Jan;139:104252
Inhibition of CDK1 attenuates neuronal apoptosis and autophagy and confers neuroprotection after chronic spinal cord injury in vivo.
Nie BX, Zhao G, Yuan XF, Yu LX, Zhang J, Yuan Y, Liu Y, Hu J, Song E, Zhou YC, Shu J
Journal of chemical neuroanatomy 2022 Jan;119:102053
Journal of chemical neuroanatomy 2022 Jan;119:102053
Iron overload inhibits cell proliferation and promotes autophagy via PARP1/SIRT1 signaling in endometriosis and adenomyosis.
Zhou Y, Zhao X, Zhang L, Xia Q, Peng Y, Zhang H, Yan D, Yang Z, Li J
Toxicology 2022 Jan 15;465:153050
Toxicology 2022 Jan 15;465:153050
Screening and identification of NOTCH1, CDKN2A, and NOS3 as differentially expressed autophagy-related genes in erectile dysfunction.
Luo C, Zhou X, Wang L, Zeng Q, Fan J, He S, Zhang H, Wei A
PeerJ 2021;9:e11986
PeerJ 2021;9:e11986
Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS.
Shang Y, Wang Q, Li J, Liu H, Zhao Q, Huang X, Dong H, Chen W, Gui R, Nie X
Frontiers in chemistry 2021;9:522708
Frontiers in chemistry 2021;9:522708
A new way for punicalagin to alleviate insulin resistance: regulating gut microbiota and autophagy.
Cao Y, Ren G, Zhang Y, Qin H, An X, Long Y, Chen J, Yang L
Food & nutrition research 2021;65
Food & nutrition research 2021;65
Metformin Inhibits Abdominal Aortic Aneurysm Formation through the Activation of the AMPK/mTOR Signaling Pathway.
He J, Li N, Fan Y, Zhao X, Liu C, Hu X
Journal of vascular research 2021;58(3):148-158
Journal of vascular research 2021;58(3):148-158
Oleanolic Acid Induces Autophagy and Apoptosis via the AMPK-mTOR Signaling Pathway in Colon Cancer.
Hu C, Cao Y, Li P, Tang X, Yang M, Gu S, Xiong K, Li T, Xiao T
Journal of oncology 2021;2021:8281718
Journal of oncology 2021;2021:8281718
Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-α Activation.
Zhang J, Cheng P, Dai W, Ji J, Wu L, Feng J, Wu J, Yu Q, Li J, Guo C
PPAR research 2021;2021:6658944
PPAR research 2021;2021:6658944
Apigenin Alleviates Liver Fibrosis by Inhibiting Hepatic Stellate Cell Activation and Autophagy via TGF-β1/Smad3 and p38/PPARα Pathways.
Ji J, Yu Q, Dai W, Wu L, Feng J, Zheng Y, Li Y, Guo C
PPAR research 2021;2021:6651839
PPAR research 2021;2021:6651839
Electroacupuncture Inhibits Autophagy of Neuron Cells in Postherpetic Neuralgia by Increasing the Expression of miR-223-3p.
Zou J, Dong X, Wang K, Shi J, Sun N
BioMed research international 2021;2021:6637693
BioMed research international 2021;2021:6637693
Pemafibrate Pretreatment Attenuates Apoptosis and Autophagy during Hepatic Ischemia-Reperfusion Injury by Modulating JAK2/STAT3β/PPARα Pathway.
Cheng Z, Guo C
PPAR research 2021;2021:6632137
PPAR research 2021;2021:6632137
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
Song Q, Liao W, Chen X, He Z, Li, Li B, Liu J, Liu L, Xiong Y, Song C, Yang S
Oxidative medicine and cellular longevity 2021;2021:6630343
Oxidative medicine and cellular longevity 2021;2021:6630343
PPARγ Plays an Important Role in Acute Hepatic Ischemia-Reperfusion Injury via AMPK/mTOR Pathway.
Wu L, Yu Q, Cheng P, Guo C
PPAR research 2021;2021:6626295
PPAR research 2021;2021:6626295
Imbalance of Autophagy and Apoptosis Induced by Oxidative Stress May Be Involved in Thyroid Damage Caused by Sleep Deprivation in Rats.
Li Y, Zhang W, Liu M, Zhang Q, Lin Z, Jia M, Liu D, Lin L
Oxidative medicine and cellular longevity 2021;2021:5645090
Oxidative medicine and cellular longevity 2021;2021:5645090
Babao Dan Reverses Multiple-Drug Resistance in Gastric Cancer Cells via Triggering Apoptosis and Autophagy and Inhibiting PI3K/AKT/mTOR Signaling.
Zhao J, Lan W, Peng J, Guan B, Liu J, Zhang M, Zhan Z, Lin J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5631942
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5631942
HIF-1α Activation Promotes Luteolysis by Enhancing ROS Levels in the Corpus Luteum of Pseudopregnant Rats.
Tang Z, Chen J, Zhang Z, Bi J, Xu R, Lin Q, Wang Z
Oxidative medicine and cellular longevity 2021;2021:1764929
Oxidative medicine and cellular longevity 2021;2021:1764929
Genome-scale CRISPRa screening identifies MTX1 as a contributor for sorafenib resistance in hepatocellular carcinoma by augmenting autophagy.
Li L, Yu S, Hu Q, Hai Y, Li Y
International journal of biological sciences 2021;17(12):3133-3144
International journal of biological sciences 2021;17(12):3133-3144
Vagal Nerve Stimulation Protects Against Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting Autophagy and Apoptosis.
Zhang LN, Zhang XW, Li CQ, Guo J, Chen YP, Chen SL
Neuropsychiatric disease and treatment 2021;17:905-913
Neuropsychiatric disease and treatment 2021;17:905-913
Progranulin Protects Against Airway Remodeling Through the Modulation of Autophagy via HMGB1 Suppression in House Dust Mite-Induced Chronic Asthma.
Liu M, Shan M, Zhang Y, Guo Z
Journal of inflammation research 2021;14:3891-3904
Journal of inflammation research 2021;14:3891-3904
Bone Autophagy: A Potential Way of Exercise-Mediated Meg3/P62/Runx2 Pathway to Regulate Bone Formation in T2DM Mice.
Chen X, Yang K, Jin X, Meng Z, Liu B, Yu H, Lu P, Wang K, Fan Z, Tang Z, Zhang F, Liu C
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:2753-2764
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:2753-2764
Combination effect of curcumin with docetaxel on the PI3K/AKT/mTOR pathway to induce autophagy and apoptosis in esophageal squamous cell carcinoma.
Deng L, Wu X, Zhu X, Yu Z, Liu Z, Wang J, Zheng Y
American journal of translational research 2021;13(1):57-72
American journal of translational research 2021;13(1):57-72
p53 Deacetylation Alleviates Sepsis-Induced Acute Kidney Injury by Promoting Autophagy.
Sun M, Li J, Mao L, Wu J, Deng Z, He M, An S, Zeng Z, Huang Q, Chen Z
Frontiers in immunology 2021;12:685523
Frontiers in immunology 2021;12:685523
Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.
Xu ZQ, Zhang JJ, Kong N, Zhang GY, Ke P, Han T, Su DF, Liu C
Frontiers in pharmacology 2021;12:676589
Frontiers in pharmacology 2021;12:676589
Neuroprotective Effects of Oxymatrine on PI3K/Akt/mTOR Pathway After Hypoxic-Ischemic Brain Damage in Neonatal Rats.
Wei W, Lu M, Lan XB, Liu N, Su WK, Dushkin AV, Yu JQ
Frontiers in pharmacology 2021;12:642415
Frontiers in pharmacology 2021;12:642415
Aiduqing formula suppresses breast cancer metastasis via inhibiting CXCL1-mediated autophagy.
Yang B, Peng F, Zhang Y, Wang X, Wang S, Zheng Y, Zhang J, Zeng Y, Wang N, Peng C, Wang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153628
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153628
Mitochondrial dysfunction and mitophagy pathway activation in hepatitis E virus-infected livers of Mongolian gerbils.
Yang Y, Tian J, Zhang H, Ma M, Li H, Liu T, Yang Y, Liu T, She R
Virus research 2021 Sep;302:198369
Virus research 2021 Sep;302:198369
Lipolysis and lipophagy play individual and interactive roles in regulating triacylglycerol and cholesterol homeostasis and mitochondrial form in zebrafish.
Han SL, Qian YC, Limbu SM, Wang J, Chen LQ, Zhang ML, Du ZY
Biochimica et biophysica acta. Molecular and cell biology of lipids 2021 Sep;1866(9):158988
Biochimica et biophysica acta. Molecular and cell biology of lipids 2021 Sep;1866(9):158988
HIV-1 Env induces pexophagy and an oxidative stress leading to uninfected CD4+ T cell death.
Daussy CF, Galais M, Pradel B, Robert-Hebmann V, Sagnier S, Pattingre S, Biard-Piechaczyk M, Espert L
Autophagy 2021 Sep;17(9):2465-2474
Autophagy 2021 Sep;17(9):2465-2474
Molecular characterization and role in virus infection of Beclin-1 in large yellow croaker (Larimichthys crocea).
Wei Z, Li X, Li W, Fu Q, Mu Y, Chen X
Fish & shellfish immunology 2021 Sep;116:30-41
Fish & shellfish immunology 2021 Sep;116:30-41
Inhibition of DNMT-1 alleviates ferroptosis through NCOA4 mediated ferritinophagy during diabetes myocardial ischemia/reperfusion injury.
Li W, Li W, Wang Y, Leng Y, Xia Z
Cell death discovery 2021 Sep 29;7(1):267
Cell death discovery 2021 Sep 29;7(1):267
WAC, a novel GBM tumor suppressor, induces GBM cell apoptosis and promotes autophagy.
Wang Y, Zhang S, Sun Q, Yuan F, Zhao L, Ye Z, Li Y, Wang R, Jiang H, Hu P, Tian D, Liu B
Medical oncology (Northwood, London, England) 2021 Sep 28;38(11):132
Medical oncology (Northwood, London, England) 2021 Sep 28;38(11):132
Activation of Autophagy Ameliorates Age-Related Neurogenesis Decline and Neurodysfunction in Adult Mice.
Yang N, Liu X, Niu X, Wang X, Jiang R, Yuan N, Wang J, Zhang C, Lim KL, Lu L
Stem cell reviews and reports 2021 Sep 21;
Stem cell reviews and reports 2021 Sep 21;
Latcripin-7A from Lentinula edodes C91-3 induces apoptosis, autophagy, and cell cycle arrest at G1 phase in human gastric cancer cells via inhibiting PI3K/Akt/mTOR signaling.
Din SRU, Nisar MA, Ramzan MN, Saleem MZ, Ghayas H, Ahmad B, Batool S, Kifayat K, Guo X, Huang M, Zhong M
European journal of pharmacology 2021 Sep 15;907:174305
European journal of pharmacology 2021 Sep 15;907:174305
Apelin/APJ signaling activates autophagy to promote human lung adenocarcinoma cell migration.
Lv D, Luo X, Chen Z, Liu J, Liu M, Li Y, Huang S, Tang M, Yang L, Lu L, Jiang J, Zhou Q, Xie F, Zhong C, Li L, Chen L
Life sciences 2021 Sep 15;281:119763
Life sciences 2021 Sep 15;281:119763
UPF1 impacts on mTOR signaling pathway and autophagy in endometrioid endometrial carcinoma.
Zhang M, Chen H, Qin P, Cai T, Li L, Chen R, Liu S, Chen H, Lin W, Chen H, Strickland AL, Xiong H, Jiang Q
Aging 2021 Sep 14;13(17):21202-21215
Aging 2021 Sep 14;13(17):21202-21215
Autophagy was activated against the damages of placentas caused by nano-copper oral exposure.
Kang M, Luo J, Zhao L, Shi F, Ye G, He X, Hao S, Yang D, Chen H, Guo H, Li Y, Tang H
Ecotoxicology and environmental safety 2021 Sep 1;220:112364
Ecotoxicology and environmental safety 2021 Sep 1;220:112364
Circular RNA circMMP1 Contributes to the Progression of Glioma Through Regulating TGIF2 Expression by Sponging miR-195-5p.
Zhang K, Wang Q, Zhao D, Liu Z
Biochemical genetics 2021 Sep 1;
Biochemical genetics 2021 Sep 1;
Effect and mechanism of action of SLP-2 on the apoptosis and autophagy of gastric cancer cells.
Yang S, Huang Y, Zhang H, Wang F, Shao L, Wang X
Oncology letters 2021 Oct;22(4):707
Oncology letters 2021 Oct;22(4):707
Hsa_circ_0004058 inhibits apoptosis of SRA01/04 cells by promoting autophagy via miR-186/ATG7 axis.
Wang Y, Wu Z, Huang Y, Zhang Y
Experimental eye research 2021 Oct;211:108721
Experimental eye research 2021 Oct;211:108721
PUF60 of Japanese flounder is regulated by pol-miR-novel_395 and involved in pathogen infection, autophagy, and apoptosis.
Li W, Guan X
Developmental and comparative immunology 2021 Oct;123:104170
Developmental and comparative immunology 2021 Oct;123:104170
The anticancer activity of root extract from Quercus acutissima Carruth. Via regulating apoptosis and autophagy in breast cancer cells.
Chen C, Ding W, Li J, Geng X, Zhang H, Sun Y
Journal of ethnopharmacology 2021 Oct 8;:114730
Journal of ethnopharmacology 2021 Oct 8;:114730
Transcription factor EB enhances autophagy and ameliorates palmitate-induced insulin resistance at least partly via upregulating AMPK activity in skeletal muscle cells.
Wang P, Li CG, Zhou X, Ding S
Clinical and experimental pharmacology & physiology 2021 Oct 6;
Clinical and experimental pharmacology & physiology 2021 Oct 6;
Hepatoprotective effects of ginsenoside Rk3 in acetaminophen-induced liver injury in mice by activation of autophagy.
Qu L, Fu R, Ma X, Fan D
Food & function 2021 Oct 4;12(19):9128-9140
Food & function 2021 Oct 4;12(19):9128-9140
Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy.
Han Y, Xiong S, Zhao H, Yang S, Yang M, Zhu X, Jiang N, Xiong X, Gao P, Wei L, Xiao Y, Sun L
Cell death & disease 2021 Oct 30;12(11):1031
Cell death & disease 2021 Oct 30;12(11):1031
Metformin sensitises hepatocarcinoma cells to methotrexate by targeting dihydrofolate reductase.
Wang Y, Lu H, Sun L, Chen X, Wei H, Suo C, Feng J, Yuan M, Shen S, Jia W, Wang Y, Zhang H, Li Z, Zhong X, Gao P
Cell death & disease 2021 Oct 2;12(10):902
Cell death & disease 2021 Oct 2;12(10):902
Co-modification with MSC membrane and PDA prevents Fe3O4-induced pulmonary toxicity in mice via AMPK-ULK1 axis.
Yao H, Yan J, Shao P, Wang Y, Liu T, Jiang J, Liu T
Toxicology letters 2021 Oct 15;351:145-154
Toxicology letters 2021 Oct 15;351:145-154
Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes the proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathway.
Chu Y, Zhu C, Yue C, Peng W, Chen W, He G, Liu C, Lv Y, Gao G, Yao K, Han R, Hu X, Zhang Y, Ye Y
Cell & bioscience 2021 Oct 13;11(1):182
Cell & bioscience 2021 Oct 13;11(1):182
Extracellular IL-37 promotes osteogenic and odontogenic differentiation of human dental pulp stem cells via autophagy.
Li N, Yan M, Chen Y, Wang Y, Wu J, Fu L, Yu J
Experimental cell research 2021 Oct 1;407(1):112780
Experimental cell research 2021 Oct 1;407(1):112780
Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells.
Wang J, Su Q, Wu Q, Chen K, Ullah A, Ghauri MA, Zhang Y
Archives of pharmacal research 2021 Nov;44(11):1025-1036
Archives of pharmacal research 2021 Nov;44(11):1025-1036
Cycloastragenol alleviates airway inflammation in asthmatic mice by inhibiting autophagy.
Zhu X, Cao Y, Su M, Chen M, Li C, Yi L, Qin J, Tulake W, Teng F, Zhong Y, Tang W, Wang S, Dong J
Molecular medicine reports 2021 Nov;24(5)
Molecular medicine reports 2021 Nov;24(5)
Extracellular vesicles originating from autophagy mediate an antibody-resistant spread of classical swine fever virus in cell culture.
Wang T, Zhang L, Liang W, Liu S, Deng W, Liu Y, Liu Y, Song M, Guo K, Zhang Y
Autophagy 2021 Nov 5;:1-17
Autophagy 2021 Nov 5;:1-17
2-Amino-3-Methylimidazo[4,5-f]quinoline Triggering Liver Damage by Inhibiting Autophagy and Inducing Endoplasmic Reticulum Stress in Zebrafish (Danio rerio).
Li D, Li Z, Zhang T, Peng B, Zhang Y, Sun H, Wang S
Toxins 2021 Nov 22;13(11)
Toxins 2021 Nov 22;13(11)
Maternal selenium deficiency suppresses proliferation, induces autophagy dysfunction and apoptosis in the placenta of mice.
Li M, Cheng W, Zhang L
Metallomics : integrated biometal science 2021 Nov 19;13(11)
Metallomics : integrated biometal science 2021 Nov 19;13(11)
Exopolysaccharides from Bifidobacterium animalis Ameliorate Escherichia coli-Induced IPEC-J2 Cell Damage via Inhibiting Apoptosis and Restoring Autophagy.
Yuan L, Chu B, Chen S, Li Y, Liu N, Zhu Y, Zhou D
Microorganisms 2021 Nov 16;9(11)
Microorganisms 2021 Nov 16;9(11)
The SGLT2 inhibitor empagliflozin negatively regulates IL-17/IL-23 axis-mediated inflammatory responses in T2DM with NAFLD via the AMPK/mTOR/autophagy pathway.
Meng Z, Liu X, Li T, Fang T, Cheng Y, Han L, Sun B, Chen L
International immunopharmacology 2021 May;94:107492
International immunopharmacology 2021 May;94:107492
Luteolin inhibits autophagy in allergic asthma by activating PI3K/Akt/mTOR signaling and inhibiting Beclin-1-PI3KC3 complex.
Wang S, Wuniqiemu T, Tang W, Teng F, Bian Q, Yi, Qin J, Zhu X, Wei Y, Dong J
International immunopharmacology 2021 May;94:107460
International immunopharmacology 2021 May;94:107460
Comparison of toxicity of Ti3 C2 and Nb2 C Mxene quantum dots (QDs) to human umbilical vein endothelial cells.
Gu M, Dai Z, Yan X, Ma J, Niu Y, Lan W, Wang X, Xu Q
Journal of applied toxicology : JAT 2021 May;41(5):745-754
Journal of applied toxicology : JAT 2021 May;41(5):745-754
Roles of endoplasmic reticulum stress in 2,2',4,4'-tetrabromodiphenylether-induced thyroid cell apoptosis and autophagy.
Ma R, Li B, Zhang C, Lei R, Zhang X, Wang C, Zhang S, Wang A
Ecotoxicology and environmental safety 2021 May;214:112077
Ecotoxicology and environmental safety 2021 May;214:112077
Chloroquine enhances catalpol's ability to promote apoptosis by inhibiting catalpol's autophagy-promoting effect on gastric cancer.
Sun F, Wang Z, Wang X
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2021 May-Jun;26(3):924-931
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2021 May-Jun;26(3):924-931
Radiosensitizing effects of curcumin alone or combined with GLUT1 siRNA on laryngeal carcinoma cells through AMPK pathway-induced autophagy.
Dai LB, Zhong JT, Shen LF, Zhou SH, Lu ZJ, Bao YY, Fan J
Journal of cellular and molecular medicine 2021 May 6;
Journal of cellular and molecular medicine 2021 May 6;
miR-338-3p inhibits autophagy in a rat model of allergic rhinitis after PM2.5 exposure through AKT/mTOR signaling by targeting UBE2Q1.
Wang JC, Huang Y, Zhang RX, Han ZJ, Zhou LL, Sun N, Dong WY, Zhuang GS
Biochemical and biophysical research communications 2021 May 21;554:1-6
Biochemical and biophysical research communications 2021 May 21;554:1-6
S-nitrosoglutathione reductase maintains mitochondrial homeostasis by promoting clearance of damaged mitochondria in porcine preimplantation embryos.
Niu YJ, Zhou D, Cui XS
Cell proliferation 2021 Mar;54(3):e12990
Cell proliferation 2021 Mar;54(3):e12990
Effects of photoperiod on morphology and function in testis and epididymis of Cricetulus barabensis.
Mou J, Xu J, Wang Z, Wang C, Yang X, Wang X, Xue H, Wu M, Xu L
Journal of cellular physiology 2021 Mar;236(3):2109-2125
Journal of cellular physiology 2021 Mar;236(3):2109-2125
Silver Nanoparticles Induced Oxidative Stress and Mitochondrial Injuries Mediated Autophagy in HC11 Cells Through Akt/AMPK/mTOR Pathway.
Hou J, Zhao L, Tang H, He X, Ye G, Shi F, Kang M, Chen H, Li Y
Biological trace element research 2021 Mar;199(3):1062-1073
Biological trace element research 2021 Mar;199(3):1062-1073
Uhrf1 regulates H3K9me2 modification of mTOR to inhibit the effect of autophagy in myocardial ischemia-reperfusion injury.
Li HG, Tian WH, Qin CL, Ye RR, Liu DH, Liu HW
Aging 2021 Mar 19;13(7):9704-9718
Aging 2021 Mar 19;13(7):9704-9718
Cadmium and molybdenum co-exposure triggers autophagy via CYP450s/ROS pathway in duck renal tubular epithelial cells.
Zhang C, Wang X, Pi S, Wei Z, Wang C, Yang F, Li G, Nie G, Hu G
The Science of the total environment 2021 Mar 10;759:143570
The Science of the total environment 2021 Mar 10;759:143570
Lead-induced cardiomyocytes apoptosis by inhibiting gap junction intercellular communication via autophagy activation.
Li C, Shi L, Peng C, Yu G, Zhang Y, Du Z
Chemico-biological interactions 2021 Mar 1;337:109331
Chemico-biological interactions 2021 Mar 1;337:109331
BIX-01294, a G9a inhibitor, suppresses cell proliferation by inhibiting autophagic flux in nasopharyngeal carcinoma cells.
Li Q, Wang L, Ji D, Bao X, Tan G, Liang X, Deng P, Pi H, Lu Y, Chen C, He M, Zhang L, Zhou Z, Yu Z, Deng A
Investigational new drugs 2021 Jun;39(3):686-696
Investigational new drugs 2021 Jun;39(3):686-696
Metformin protects cardiomyocytes against oxygen-glucose deprivation injury by promoting autophagic flux through AMPK pathway.
Wu S, Zhang H, Chen N, Zhang C, Guo X
Journal of drug targeting 2021 Jun;29(5):551-561
Journal of drug targeting 2021 Jun;29(5):551-561
Decreased expression of IDH1 by chronic unpredictable stress suppresses proliferation and accelerates senescence of granulosa cells through ROS activated MAPK signaling pathways.
Sun J, Guo Y, Fan Y, Wang Q, Zhang Q, Lai D
Free radical biology & medicine 2021 Jun;169:122-136
Free radical biology & medicine 2021 Jun;169:122-136
Hydrogen sulfide alleviates apoptosis and autophagy induced by beryllium sulfate in 16HBE cells.
Liu YP, Yuan XY, Li XY, Wang Y, Sun ZB, Deng WH, Lei YD, Huang L, Jiang TY, Zhang ZH
Journal of applied toxicology : JAT 2021 Jun 6;
Journal of applied toxicology : JAT 2021 Jun 6;
Protective effect of scorpion venom heat-resistant synthetic peptide against PM2.5-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
Xu X, Xu H, Ren F, Huang L, Xu J, Li F
Journal of neuroimmunology 2021 Jun 15;355:577567
Journal of neuroimmunology 2021 Jun 15;355:577567
Metformin attenuates atherosclerosis and plaque vulnerability by upregulating KLF2-mediated autophagy in apoE-/- mice.
Wu H, Feng K, Zhang C, Zhang H, Zhang J, Hua Y, Dong Z, Zhu Y, Yang S, Ma C
Biochemical and biophysical research communications 2021 Jun 11;557:334-341
Biochemical and biophysical research communications 2021 Jun 11;557:334-341
Neferine promotes the apoptosis of HNSCC through the accumulation of p62/SQSTM1 caused by autophagic flux inhibition.
Zhu F, Li X, Tang X, Jiang J, Han Y, Li Y, Ma C, Liu Z, He Y
International journal of molecular medicine 2021 Jul;48(1)
International journal of molecular medicine 2021 Jul;48(1)
HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance.
Zong B, Sun L, Peng Y, Wang Y, Yu Y, Lei J, Zhang Y, Guo S, Li K, Liu S
Oncology reports 2021 Jul;46(1)
Oncology reports 2021 Jul;46(1)
The mechanism of 5-aminolevulinic acid photodynamic therapy in promoting endoplasmic reticulum stress in the treatment of HR-HPV-infected HeLa cells.
Li Z, Teng M, Wang Y, Wang Q, Feng Y, Xiao Z, Li C, Zeng K
Photodermatology, photoimmunology & photomedicine 2021 Jul;37(4):348-359
Photodermatology, photoimmunology & photomedicine 2021 Jul;37(4):348-359
Hydrogen-Rich Medium Regulates Cr(VI)-Induced ER Stress and Autophagy Signaling in DF-1 Cells.
Liu K, Cui Y, Li H, Qi C, Cheng G, Gao X, Zhang Z, Liu Y, Liu J
Biological trace element research 2021 Jul 30;
Biological trace element research 2021 Jul 30;
Hypoxic preconditioning rejuvenates mesenchymal stem cells and enhances neuroprotection following intracerebral hemorrhage via the miR-326-mediated autophagy.
Liu J, He J, Ge L, Xiao H, Huang Y, Zeng L, Jiang Z, Lu M, Hu Z
Stem cell research & therapy 2021 Jul 22;12(1):413
Stem cell research & therapy 2021 Jul 22;12(1):413
Rev-erbα exacerbates hepatic steatosis in alcoholic liver diseases through regulating autophagy.
Liu Q, Xu L, Wu M, Zhou Y, Yang J, Huang C, Xu T, Li J, Zhang L
Cell & bioscience 2021 Jul 10;11(1):129
Cell & bioscience 2021 Jul 10;11(1):129
S100A8 promotes chemoresistance via augmenting autophagy in B‑cell lymphoma cells.
Zhang L, Zhou S, Zhou T, Yuan K, Li X, Tang J
Oncology reports 2021 Jan;45(1):151-158
Oncology reports 2021 Jan;45(1):151-158
Induction of autophagy by Beclin-1 in granulosa cells contributes to follicular progesterone elevation in ovarian endometriosis.
Ding Y, Zhu Q, He Y, Lu Y, Wang Y, Qi J, Wu H, Xu R, Li J, Li X, Sun Y
Translational research : the journal of laboratory and clinical medicine 2021 Jan;227:15-29
Translational research : the journal of laboratory and clinical medicine 2021 Jan;227:15-29
Radix Polygalae extract exerts antidepressant effects in behavioral despair mice and chronic restraint stress-induced rats probably by promoting autophagy and inhibiting neuroinflammation.
Zhou Y, Yan M, Pan R, Wang Z, Tao X, Li C, Xia T, Liu X, Chang Q
Journal of ethnopharmacology 2021 Jan 30;265:113317
Journal of ethnopharmacology 2021 Jan 30;265:113317
Resveratrol attenuates cigarette smoke induced endothelial apoptosis by activating Notch1 signaling mediated autophagy.
Zong DD, Liu XM, Li JH, Ouyang RY, Long YJ, Chen P, Chen Y
Respiratory research 2021 Jan 19;22(1):22
Respiratory research 2021 Jan 19;22(1):22
Ketogenic diet induces autophagy to alleviate bleomycin-induced pulmonary fibrosis in murine models.
Mu E, Wang J, Chen L, Lin S, Chen J, Huang X
Experimental lung research 2021 Feb;47(1):26-36
Experimental lung research 2021 Feb;47(1):26-36
The reduction of lipid-sourced energy production caused by ATGL inhibition cannot be compensated by activation of HSL, autophagy, and utilization of other nutrients in fish.
Han SL, Liu Y, Limbu SM, Chen LQ, Zhang ML, Du ZY
Fish physiology and biochemistry 2021 Feb;47(1):173-188
Fish physiology and biochemistry 2021 Feb;47(1):173-188
PPARγ/NF-κB and TGF-β1/Smad pathway are involved in the anti-fibrotic effects of levo-tetrahydropalmatine on liver fibrosis.
Yu Q, Cheng P, Wu J, Guo C
Journal of cellular and molecular medicine 2021 Feb;25(3):1645-1660
Journal of cellular and molecular medicine 2021 Feb;25(3):1645-1660
Overexpression of lncRNA Dancr inhibits apoptosis and enhances autophagy to protect cardiomyocytes from endoplasmic reticulum stress injury via sponging microRNA-6324.
Li J, Xie J, Wang YZ, Gan YR, Wei L, Ding GW, Ding YH, Xie DX
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Inhibition of autophagy aggravates molybdenum-induced mitochondrial dysfunction by aggravating oxidative stress in duck renal tubular epithelial cells.
Zhuang J, Nie G, Hu R, Wang C, Xing C, Li G, Hu G, Yang F, Zhang C
Ecotoxicology and environmental safety 2021 Feb;209:111771
Ecotoxicology and environmental safety 2021 Feb;209:111771
Fe3O4 magnetic nanoparticles ameliorate albumin-induced tubulointerstitial fibrosis by autophagy related to Rab7.
Liu L, Xu Q, Zhang L, Sun H, Ding F, Li Y, Chen P
Colloids and surfaces. B, Biointerfaces 2021 Feb;198:111470
Colloids and surfaces. B, Biointerfaces 2021 Feb;198:111470
CircCDK8 regulates osteogenic differentiation and apoptosis of PDLSCs by inducing ER stress/autophagy during hypoxia.
Zheng J, Zhu X, He Y, Hou S, Liu T, Zhi K, Hou T, Gao L
Annals of the New York Academy of Sciences 2021 Feb;1485(1):56-70
Annals of the New York Academy of Sciences 2021 Feb;1485(1):56-70
Escalating dose-multiple binge methamphetamine treatment elicits neurotoxicity, altering gut microbiota and fecal metabolites in mice.
Chen LJ, Zhi X, Zhang KK, Wang LB, Li JH, Liu JL, Xu LL, Yoshida JS, Xie XL, Wang Q
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Feb;148:111946
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Feb;148:111946
RabGEF1 functions as an oncogene in U251 glioblastoma cells and is involved in regulating AKT and Erk pathways.
Fan H, Xin T, Dong X, Yang F, Zhang R, Feng S, He D, Guo H, Pang Q
Experimental and molecular pathology 2021 Feb;118:104571
Experimental and molecular pathology 2021 Feb;118:104571
Overexpression of miR-431 attenuates hypoxia/reoxygenation-induced myocardial damage via autophagy-related 3.
Zhou K, Xu Y, Wang Q, Dong L
Acta biochimica et biophysica Sinica 2021 Feb 4;53(2):140-148
Acta biochimica et biophysica Sinica 2021 Feb 4;53(2):140-148
SIRT1 attenuates sepsis-induced acute kidney injury via Beclin1 deacetylation-mediated autophagy activation.
Deng Z, Sun M, Wu J, Fang H, Cai S, An S, Huang Q, Chen Z, Wu C, Zhou Z, Hu H, Zeng Z
Cell death & disease 2021 Feb 26;12(2):217
Cell death & disease 2021 Feb 26;12(2):217
QiShenYiQi pill activates autophagy to attenuate reactive myocardial fibrosis via the PI3K/AKT/mTOR pathway.
Lv S, Yuan P, Lu C, Dong J, Li M, Qu F, Zhu Y, Zhang J
Aging 2021 Feb 11;13(4):5525-5538
Aging 2021 Feb 11;13(4):5525-5538
Vascular endothelial cell-secreted exosomes facilitate osteoarthritis pathogenesis by promoting chondrocyte apoptosis.
Yang RZ, Zheng HL, Xu WN, Zheng XF, Li B, Jiang LS, Jiang SD
Aging 2021 Feb 1;13(3):4647-4662
Aging 2021 Feb 1;13(3):4647-4662
The variations of endophilin A2-FoxO3a-autophagy signal in angiotensin II-induced dopaminergic neuron injury mouse model and by biochanin A.
Yu YG, Han JH, Xue HX, Li WZ, Wu WN, Yin YY
Canadian journal of physiology and pharmacology 2021 Dec;99(12):1298-1307
Canadian journal of physiology and pharmacology 2021 Dec;99(12):1298-1307
Long-term carbon black inhalation induced the inflammation and autophagy of cerebellum in rats.
Zhang H, Lou N, Liu XY, Li CZ, Xu K, Xu FF, Su AC, Zhang LY, Zhang M, Zhang JG
Neurotoxicology 2021 Dec;87:120-127
Neurotoxicology 2021 Dec;87:120-127
MEHP induces pyroptosis and autophagy alternation by cathepsin B activation in INS-1 cells.
Jiang L, Qiu T, Yao X, Chen H, Yao K, Sun X, Yang G, Jiang L, Zhang C, Wang N, Zhang H, Liu X
Environmental science and pollution research international 2021 Dec;28(47):66628-66642
Environmental science and pollution research international 2021 Dec;28(47):66628-66642
HBx induces hepatocellular carcinogenesis through ARRB1-mediated autophagy to drive the G1/S cycle.
Lei Y, Xu X, Liu H, Chen L, Zhou H, Jiang J, Yang Y, Wu B
Autophagy 2021 Dec;17(12):4423-4441
Autophagy 2021 Dec;17(12):4423-4441
miR-142-3p and HMGB1 Are Negatively Regulated in Proliferation, Apoptosis, Migration, and Autophagy of Cartilage Endplate Cells.
Wang B, Ji D, Xing W, Li F, Huang Z, Zheng W, Xue J, Zhu Y, Yang X
Cartilage 2021 Dec;13(2_suppl):592S-603S
Cartilage 2021 Dec;13(2_suppl):592S-603S
PIAS1 alleviates diabetic peripheral neuropathy through SUMOlation of PPAR-γ and miR-124-induced downregulation of EZH2/STAT3.
Hou Z, Chen J, Yang H, Hu X, Yang F
Cell death discovery 2021 Dec 2;7(1):372
Cell death discovery 2021 Dec 2;7(1):372
The unique Akt inhibitor SC66 suppressed AMPK activity and abolished autophagy through the EGFR-p62 pathway.
Hou B, Li E, Liang J, Liu S, Yang H, Liu L, Jiang X
Cell biology international 2021 Dec 2;
Cell biology international 2021 Dec 2;
6-Shogaol from ginger shows anti-tumor effect in cervical carcinoma via PI3K/Akt/mTOR pathway.
Pei XD, He ZL, Yao HL, Xiao JS, Li L, Gu JZ, Shi PZ, Wang JH, Jiang LH
European journal of nutrition 2021 Aug;60(5):2781-2793
European journal of nutrition 2021 Aug;60(5):2781-2793
Circadian misalignment promotes vascular smooth muscle cell apoptosis via defective autophagy.
Guo Z, Yu B, Li X, Yang X, Wang C, Fan L
Journal of molecular histology 2021 Aug;52(4):799-808
Journal of molecular histology 2021 Aug;52(4):799-808
W436, a novel SMART derivative, exhibits anti-hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.
Man S, Wu Z, Sun R, Guan Q, Li Z, Zuo D, Zhang W, Wu Y
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22831
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22831
Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.
Ma L, Li C, Lian S, Xu B, Lv H, Liu Y, Lu J, Ji H, Li S, Guo J, Yang H
Journal of cellular and molecular medicine 2021 Aug;25(16):8015-8027
Journal of cellular and molecular medicine 2021 Aug;25(16):8015-8027
EGCG synergizes the therapeutic effect of irinotecan through enhanced DNA damage in human colorectal cancer cells.
Wu W, Dong J, Gou H, Geng R, Yang X, Chen D, Xiang B, Zhang Z, Ren S, Chen L, Liu J
Journal of cellular and molecular medicine 2021 Aug;25(16):7913-7921
Journal of cellular and molecular medicine 2021 Aug;25(16):7913-7921
Hsa_circ_0092276 promotes doxorubicin resistance in breast cancer cells by regulating autophagy via miR-348/ATG7 axis.
Wang Q, Liang D, Shen P, Yu Y, Yan Y, You W
Translational oncology 2021 Aug;14(8):101045
Translational oncology 2021 Aug;14(8):101045
Synthesis, SAR study, and bioactivity evaluation of a series of Quinoline-Indole-Schiff base derivatives: Compound 10E as a new Nur77 exporter and autophagic death inducer.
Li B, Yao J, He F, Liu J, Lin Z, Liu S, Wang W, Wu T, Huang J, Chen K, Fang M, Chen J, Zeng JZ
Bioorganic chemistry 2021 Aug;113:105008
Bioorganic chemistry 2021 Aug;113:105008
Mammalian target of rapamycin signaling pathway is involved in synaptic plasticity of the spinal dorsal horn and neuropathic pain in rats by regulating autophagy.
Hu J, Chen X, Cheng J, Kong F, Xia H, Wu J
Neuroreport 2021 Aug 4;32(11):925-935
Neuroreport 2021 Aug 4;32(11):925-935
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
Xie C, Zhou X, Liang C, Li X, Ge M, Chen Y, Yin J, Zhu J, Zhong C
Journal of experimental & clinical cancer research : CR 2021 Aug 24;40(1):266
Journal of experimental & clinical cancer research : CR 2021 Aug 24;40(1):266
Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility.
Lei Y, Zhang X, Xu Q, Liu S, Li C, Jiang H, Lin H, Kong E, Liu J, Qi S, Li H, Xu W, Lu K
Developmental cell 2021 Aug 23;56(16):2313-2328.e7
Developmental cell 2021 Aug 23;56(16):2313-2328.e7
LncRNA CCAT1 Upregulates ATG5 to Enhance Autophagy and Promote Gastric Cancer Development by Absorbing miR-140-3p.
Yang F, Peng ZX, Ji WD, Yu JD, Qian C, Liu JD, Fang GE
Digestive diseases and sciences 2021 Aug 21;
Digestive diseases and sciences 2021 Aug 21;
Advanced oxidation protein products impair autophagic flux in macrophage by inducing lysosomal dysfunction via activation of PI3K-Akt-mTOR pathway in Crohn's disease.
Liao Y, Xu J, Qin B, Shi J, Qin C, Xie F, Ou S, Tang J, Wang W, Wu F, Bai L
Free radical biology & medicine 2021 Aug 20;172:33-47
Free radical biology & medicine 2021 Aug 20;172:33-47
Sodium valproate increases activity of the sirtuin pathway resulting in beneficial effects for spinocerebellar ataxia-3 in vivo.
Watchon M, Luu L, Robinson KJ, Yuan KC, De Luca A, Suddull HJ, Tym MC, Guillemin GJ, Cole NJ, Nicholson GA, Chung RS, Lee A, Laird AS
Molecular brain 2021 Aug 20;14(1):128
Molecular brain 2021 Aug 20;14(1):128
Enhancement of TEX264-Mediated ER-Phagy Contributes to the Therapeutic Effect of Glycycoumarin against APA Hepatotoxicity in Mice.
Yan M, Wang Z, Xia T, Jin S, Liu Y, Hu H, Chang Q
Biomedicines 2021 Aug 2;9(8)
Biomedicines 2021 Aug 2;9(8)
Circular RNA ubiquitin-associated protein 2 enhances autophagy and promotes colorectal cancer progression and metastasis via miR-582-5p/FOXO1 signaling.
Chen F, Guo L, Di J, Li M, Dong D, Pei D
Journal of genetics and genomics = Yi chuan xue bao 2021 Aug 18;
Journal of genetics and genomics = Yi chuan xue bao 2021 Aug 18;
Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy.
Jiang Y, Zhou Y, Xu W, Wang X, Jin H, Bao X, Lu C
Cell biology and toxicology 2021 Aug 17;
Cell biology and toxicology 2021 Aug 17;
Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy.
Luo L, Jian X, Sun H, Qin J, Wang Y, Zhang J, Shen Z, Yang D, Li C, Zhao P, Liu M, Tian Z, Zhou Y
Stem cells (Dayton, Ohio) 2021 Apr;39(4):467-481
Stem cells (Dayton, Ohio) 2021 Apr;39(4):467-481
Involvement of Mitophagy in Aluminum Oxide Nanoparticle-Induced Impairment of Learning and Memory in Mice.
Huang T, Guo W, Wang Y, Chang L, Shang N, Chen J, Fan R, Zhang L, Gao X, Niu Q, Zhang Q
Neurotoxicity research 2021 Apr;39(2):378-391
Neurotoxicity research 2021 Apr;39(2):378-391
Expression of long-chain noncoding RNA GAS5 in osteoarthritis and its effect on apoptosis and autophagy of osteoarthritis chondrocytes.
Ji Q, Qiao X, Liu Y, Wang D
Histology and histopathology 2021 Apr;36(4):475-484
Histology and histopathology 2021 Apr;36(4):475-484
Hydrogen sulfide ameliorates doxorubicin‑induced myocardial fibrosis in rats via the PI3K/AKT/mTOR pathway.
Nie L, Liu M, Chen J, Wu Q, Li Y, Yi J, Zheng X, Zhang J, Chu C, Yang J
Molecular medicine reports 2021 Apr;23(4)
Molecular medicine reports 2021 Apr;23(4)
Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process.
Tan YZ, Xu XY, Dai JM, Yin Y, He XT, Zhang YL, Zhu TX, An Y, Tian BM, Chen FM
Stem cell research & therapy 2021 Apr 29;12(1):254
Stem cell research & therapy 2021 Apr 29;12(1):254
Reduction of Autophagosome Overload Attenuates Neuronal Cell Death After Traumatic Brain Injury.
Quan X, Song L, Zheng X, Liu S, Ding H, Li S, Xu G, Li X, Liu L
Neuroscience 2021 Apr 15;460:107-119
Neuroscience 2021 Apr 15;460:107-119
Pentraxin 3 Promotes Glioblastoma Progression by Negative Regulating Cells Autophagy.
Wang Z, Wang X, Zhang N, Zhang H, Dai Z, Zhang M, Feng S, Cheng Q
Frontiers in cell and developmental biology 2020;8:795
Frontiers in cell and developmental biology 2020;8:795
HDAC6 Regulates the Fusion of Autophagosome and Lysosome to Involve in Odontoblast Differentiation.
Zhan Y, Wang H, Zhang L, Pei F, Chen Z
Frontiers in cell and developmental biology 2020;8:605609
Frontiers in cell and developmental biology 2020;8:605609
Dendrobium nobile Lindl. Alkaloids Ameliorate Cognitive Dysfunction in Senescence Accelerated SAMP8 Mice by Decreasing Amyloid-β Aggregation and Enhancing Autophagy Activity.
Lv LL, Liu B, Liu J, Li LS, Jin F, Xu YY, Wu Q, Liu J, Shi JS
Journal of Alzheimer's disease : JAD 2020;76(2):657-669
Journal of Alzheimer's disease : JAD 2020;76(2):657-669
Dioscin Protects against Aβ1-42 Oligomers-Induced Neurotoxicity via the Function of SIRT3 and Autophagy.
Zhang Z, Han K, Wang C, Sun C, Jia N
Chemical & pharmaceutical bulletin 2020;68(8):717-725
Chemical & pharmaceutical bulletin 2020;68(8):717-725
Geniposide Enhances Macrophage Autophagy through Downregulation of TREM2 in Atherosclerosis.
Xu YL, Liu XY, Cheng SB, He PK, Hong MK, Chen YY, Zhou FH, Jia YH
The American journal of Chinese medicine 2020;48(8):1821-1840
The American journal of Chinese medicine 2020;48(8):1821-1840
Autophagy Contributes to Host Immunity and Protection against Zika Virus Infection via Type I IFN Signaling.
Huang Y, Wang Y, Meng S, Chen Z, Kong H, Pan T, Lu G, Li X
Mediators of inflammation 2020;2020:9527147
Mediators of inflammation 2020;2020:9527147
Protective Role of Coenzyme Q10 in Acute Sepsis-Induced Liver Injury in BALB/c Mice.
Li QW, Yang Q, Liu HY, Wu YL, Hao YH, Zhang XQ
BioMed research international 2020;2020:7598375
BioMed research international 2020;2020:7598375
Bergenin Attenuates Hepatic Fibrosis by Regulating Autophagy Mediated by the PPAR-γ/TGF-β Pathway.
Xia Y, Li J, Chen K, Feng J, Guo C
PPAR research 2020;2020:6694214
PPAR research 2020;2020:6694214
Autophagy Triggered by Oxidative Stress Appears to Be Mediated by the AKT/mTOR Signaling Pathway in the Liver of Sleep-Deprived Rats.
Li Y, Zhang Y, Ji G, Shen Y, Zhao N, Liang Y, Wang Z, Liu M, Lin L
Oxidative medicine and cellular longevity 2020;2020:6181630
Oxidative medicine and cellular longevity 2020;2020:6181630
The Class III PI3K/Beclin-1 Autophagic Pathway Participates in the mmLDL-Induced Upregulation of ETA Receptor in Mouse Mesenteric Arteries.
Xie X, Chen C, Xu CB, Lin J, Cao L, Chen G, Li J
Advances in pharmacological and pharmaceutical sciences 2020;2020:5070436
Advances in pharmacological and pharmaceutical sciences 2020;2020:5070436
Alantolactone inhibits cell autophagy and promotes apoptosis via AP2M1 in acute lymphoblastic leukemia.
Shi C, Lan W, Wang Z, Yang D, Wei J, Liu Z, Teng Y, Gu M, Yuan T, Cao F, Zhou J, Li Y
Cancer cell international 2020;20:442
Cancer cell international 2020;20:442
Deletion of mitochondrial uncoupling protein 2 exacerbates mitophagy and cell apoptosis after cerebral ischemia and reperfusion injury in mice.
He M, Zhang T, Fan Y, Ma Y, Zhang J, Jing L, Li PA
International journal of medical sciences 2020;17(17):2869-2878
International journal of medical sciences 2020;17(17):2869-2878
Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.
Deng X, Liu J, Liu L, Sun X, Huang J, Dong J
International journal of biological sciences 2020;16(8):1403-1416
International journal of biological sciences 2020;16(8):1403-1416
The effect of autophagy and mitochondrial fission on Harderian gland is greater than apoptosis in male hamsters during different photoperiods.
Xu JH, Wang Z, Mou JJ, Zhao XY, Geng XC, Wu M, Xue HL, Chen L, Xu LX
PloS one 2020;15(11):e0241561
PloS one 2020;15(11):e0241561
Punicalagin Inhibits Tert-Butyl Hydroperoxide-Induced Apoptosis and Extracellular Matrix Degradation in Chondrocytes by Activating Autophagy and Ameliorates Murine Osteoarthritis.
Kong J, Wang J, Gong X, Zheng X, Chen T
Drug design, development and therapy 2020;14:5521-5533
Drug design, development and therapy 2020;14:5521-5533
Baicalin Protects Human OA Chondrocytes Against IL-1β-Induced Apoptosis and ECM Degradation by Activating Autophagy via MiR-766-3p/AIFM1 Axis.
Li Z, Cheng J, Liu J
Drug design, development and therapy 2020;14:2645-2655
Drug design, development and therapy 2020;14:2645-2655
Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway.
Xiang S, Chen K, Xu L, Wang T, Guo C
Drug design, development and therapy 2020;14:129-143
Drug design, development and therapy 2020;14:129-143
The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis.
Shang Y, Wang Q, Li J, Zhao Q, Huang X, Dong H, Liu H, Zhang Y, Zhang J, Gui R, Nie X
OncoTargets and therapy 2020;13:473-486
OncoTargets and therapy 2020;13:473-486
Metformin Promotes Beclin1-Dependent Autophagy to Inhibit the Progression of Gastric Cancer.
Liu S, Yue C, Chen H, Chen Y, Li G
OncoTargets and therapy 2020;13:4445-4455
OncoTargets and therapy 2020;13:4445-4455
The Effects of Puerarin on Autophagy Through Regulating of the PERK/eIF2α/ATF4 Signaling Pathway Influences Renal Function in Diabetic Nephropathy.
Xu X, Chen B, Huang Q, Wu Y, Liang T
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:2583-2592
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:2583-2592
Long Noncoding RNA TUG1 Promotes Autophagy-Associated Paclitaxel Resistance by Sponging miR-29b-3p in Ovarian Cancer Cells.
Gu L, Li Q, Liu H, Lu X, Zhu M
OncoTargets and therapy 2020;13:2007-2019
OncoTargets and therapy 2020;13:2007-2019
Chlorin A-mediated photodynamic therapy induced apoptosis in human cholangiocarcinoma cells via impaired autophagy flux.
He C, Xia J, Gao Y, Chen Z, Wan X
American journal of translational research 2020;12(9):5080-5094
American journal of translational research 2020;12(9):5080-5094
Isovitexin modulates autophagy in Alzheimer's disease via miR-107 signalling.
Cheng J, Wang G, Zhang N, Li F, Shi L, Li H
Translational neuroscience 2020;11(1):391-401
Translational neuroscience 2020;11(1):391-401
Eugenol Attenuates Cerebral Ischemia-Reperfusion Injury by Enhancing Autophagy via AMPK-mTOR-P70S6K Pathway.
Sun X, Wang D, Zhang T, Lu X, Duan F, Ju L, Zhuang X, Jiang X
Frontiers in pharmacology 2020;11:84
Frontiers in pharmacology 2020;11:84
Hyperoside Protects Human Umbilical Vein Endothelial Cells Against Anticardiolipin Antibody-Induced Injury by Activating Autophagy.
Wei A, Xiao H, Xu G, Yu X, Guo J, Jing Z, Shi S, Song Y
Frontiers in pharmacology 2020;11:762
Frontiers in pharmacology 2020;11:762
Staphylococcus aureus Avoids Autophagy Clearance of Bovine Mammary Epithelial Cells by Impairing Lysosomal Function.
Geng N, Wang X, Yu X, Wang R, Zhu Y, Zhang M, Liu J, Liu Y
Frontiers in immunology 2020;11:746
Frontiers in immunology 2020;11:746
Empagliflozin Alleviates Hepatic Steatosis by Activating the AMPK-TET2-Autophagy Pathway in vivo and in vitro.
Li T, Fang T, Xu L, Liu X, Li X, Xue M, Yu X, Sun B, Chen L
Frontiers in pharmacology 2020;11:622153
Frontiers in pharmacology 2020;11:622153
Cardamonin Reduces Acetaminophen-Induced Acute Liver Injury in Mice via Activating Autophagy and NFE2L2 Signaling.
Xu Q, Fan Y, Loor JJ, Liang Y, Sun X, Jia H, Zhao C, Xu C
Frontiers in pharmacology 2020;11:601716
Frontiers in pharmacology 2020;11:601716
miR-433 Inhibits Neuronal Growth and Promotes Autophagy in Mouse Hippocampal HT-22 Cell Line.
Xu C, Bai Q, Wang C, Meng Q, Gu Y, Wang Q, Xu W, Han Y, Qin Y, Jia S, Zhang J, Xu J, Li J, Chen M, Wang F
Frontiers in pharmacology 2020;11:536913
Frontiers in pharmacology 2020;11:536913
Morroniside Inhibits H2O2-Induced Podocyte Apoptosis by Down-Regulating NOX4 Expression Controlled by Autophagy In Vitro.
Gao X, Liu Y, Wang L, Sai N, Liu Y, Ni J
Frontiers in pharmacology 2020;11:533809
Frontiers in pharmacology 2020;11:533809
Singapore Grouper Iridovirus (SGIV) Inhibited Autophagy for Efficient Viral Replication.
Li C, Wang L, Liu J, Yu Y, Huang Y, Huang X, Wei J, Qin Q
Frontiers in microbiology 2020;11:1446
Frontiers in microbiology 2020;11:1446
Liraglutide Ameliorates Erectile Dysfunction via Regulating Oxidative Stress, the RhoA/ROCK Pathway and Autophagy in Diabetes Mellitus.
Yuan P, Ma D, Gao X, Wang J, Li R, Liu Z, Wang T, Wang S, Liu J, Liu X
Frontiers in pharmacology 2020;11:1257
Frontiers in pharmacology 2020;11:1257
Inhibition of JNK-Mediated Autophagy Promotes Proscillaridin A- Induced Apoptosis via ROS Generation, Intracellular Ca+2 Oscillation and Inhibiting STAT3 Signaling in Breast Cancer Cells.
Saleem MZ, Alshwmi M, Zhang H, Din SRU, Nisar MA, Khan M, Alam S, Alam G, Jin L, Ma T
Frontiers in pharmacology 2020;11:01055
Frontiers in pharmacology 2020;11:01055
LETM1 Knockdown Promotes Autophagy and Apoptosis Through AMP-Activated Protein Kinase Phosphorylation-Mediated Beclin-1/Bcl-2 Complex Dissociation in Hepatocellular Carcinoma.
Zhou B, Yang C, Yan X, Shi Z, Xiao H, Wei X, Jiang N, Wu Z
Frontiers in oncology 2020;10:606790
Frontiers in oncology 2020;10:606790
Disulfiram Chelated With Copper Inhibits the Growth of Gastric Cancer Cells by Modulating Stress Response and Wnt/β-catenin Signaling.
Wang L, Chai X, Wan R, Zhang H, Zhou C, Xiang L, Paul ME, Li Y
Frontiers in oncology 2020;10:595718
Frontiers in oncology 2020;10:595718
NLRP6 contributes to inflammation and brain injury following intracerebral haemorrhage by activating autophagy.
Xiao H, Chen H, Jiang R, Zhang L, Wang L, Gan H, Jiang N, Zhao J, Zhai X, Liang P
Journal of molecular medicine (Berlin, Germany) 2020 Sep;98(9):1319-1331
Journal of molecular medicine (Berlin, Germany) 2020 Sep;98(9):1319-1331
Neferine induces apoptosis by modulating the ROS‑mediated JNK pathway in esophageal squamous cell carcinoma.
An K, Zhang Y, Liu Y, Yan S, Hou Z, Cao M, Liu G, Dong C, Gao J, Liu G
Oncology reports 2020 Sep;44(3):1116-1126
Oncology reports 2020 Sep;44(3):1116-1126
Effect of combination of curcumin and GLUT-1 AS-ODN on radiosensitivity of laryngeal carcinoma through regulating autophagy.
Dai LB, Yu Q, Zhou SH, Bao YY, Zhong JT, Shen LF, Lu ZJ, Fan J, Huang YP
Head & neck 2020 Sep;42(9):2287-2297
Head & neck 2020 Sep;42(9):2287-2297
Pretreatment with the ALDH2 activator Alda‑1 protects rat livers from ischemia/reperfusion injury by inducing autophagy.
Liu Z, Ye S, Zhong X, Wang W, Lai CH, Yang W, Yue P, Luo J, Huang X, Zhong Z, Xiong Y, Fan X, Li L, Wang Y, Ye Q
Molecular medicine reports 2020 Sep;22(3):2373-2385
Molecular medicine reports 2020 Sep;22(3):2373-2385
Mycobacterium tuberculosis infection increases the number of osteoclasts and inhibits osteoclast apoptosis by regulating TNF-α-mediated osteoclast autophagy.
Liu W, Zhou J, Niu F, Pu F, Wang Z, Huang M, Zhao X, Yang L, Tao P, Xia P, Feng J
Experimental and therapeutic medicine 2020 Sep;20(3):1889-1898
Experimental and therapeutic medicine 2020 Sep;20(3):1889-1898
Paecilomyces cicadae-fermented Radix astragali activates podocyte autophagy by attenuating PI3K/AKT/mTOR pathways to protect against diabetic nephropathy in mice.
Yang F, Qu Q, Zhao C, Liu X, Yang P, Li Z, Han L, Shi X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110479
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110479
Knockdown of TXNDC9 induces apoptosis and autophagy in glioma and mediates cell differentiation by p53 activation.
Zheng T, Chen K, Zhang X, Feng H, Shi Y, Liu L, Zhang J, Chen Y
Aging 2020 Sep 8;12(18):18649-18659
Aging 2020 Sep 8;12(18):18649-18659
Discoidin Domain Receptors 1 Inhibition Alleviates Osteoarthritis via Enhancing Autophagy.
Chou HC, Chen CH, Chou LY, Cheng TL, Kang L, Chuang SC, Lin YS, Ho ML, Wang YH, Lin SY, Wang CZ
International journal of molecular sciences 2020 Sep 23;21(19)
International journal of molecular sciences 2020 Sep 23;21(19)
NOD2/c-Jun NH2-Terminal Kinase Triggers Mycoplasma ovipneumoniae-Induced Macrophage Autophagy.
Luo H, Wu X, Xu Z, Hao X, Wang Y, Li M
Journal of bacteriology 2020 Sep 23;202(20)
Journal of bacteriology 2020 Sep 23;202(20)
Zinc oxide nanoparticles effectively regulate autophagic cell death by activating autophagosome formation and interfering with their maturation.
Liu Z, Lv X, Xu L, Liu X, Zhu X, Song E, Song Y
Particle and fibre toxicology 2020 Sep 18;17(1):46
Particle and fibre toxicology 2020 Sep 18;17(1):46
Inhibition of autophagy enhances timosaponin AIII-induced lung cancer cell apoptosis and anti-tumor effect in vitro and in vivo.
Liu J, Deng X, Sun X, Dong J, Huang J
Life sciences 2020 Sep 15;257:118040
Life sciences 2020 Sep 15;257:118040
Clusterin contributes to hepatitis C virus-related hepatocellular carcinoma by regulating autophagy.
Fu N, Du H, Li D, Lu Y, Li W, Wang Y, Kong L, Du J, Zhao S, Ren W, Han F, Wang R, Zhang Y, Nan Y
Life sciences 2020 Sep 1;256:117911
Life sciences 2020 Sep 1;256:117911
QiShenYiQi pill improves the reparative myocardial fibrosis by regulating autophagy.
Lv S, Yuan P, Dong J, Lu C, Li M, Qu F, Zhu Y, Yuan Z, Zhang J
Journal of cellular and molecular medicine 2020 Oct;24(19):11283-11293
Journal of cellular and molecular medicine 2020 Oct;24(19):11283-11293
Effect of autophagy on irradiation‑induced damage in osteoblast‑like MC3T3‑E1 cells.
Li R, Yang W, Hu X, Zhou D, Huang K, Wang C, Li Y, Liu B
Molecular medicine reports 2020 Oct;22(4):3473-3481
Molecular medicine reports 2020 Oct;22(4):3473-3481
STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I.
Zhou C, Qian X, Hu M, Zhang R, Liu N, Huang Y, Yang J, Zhang J, Bai H, Yang Y, Wang Y, Ali D, Michalak M, Chen XZ, Tang J
Autophagy 2020 Oct;16(10):1786-1806
Autophagy 2020 Oct;16(10):1786-1806
3-Chloro-1, 2-propanediol inhibits autophagic flux by impairment of lysosomal function in HepG2 cells.
Lu J, Lu J, Chen Y, Feng Z, Liu S, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Oct;144:111575
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Oct;144:111575
Evaluation of toxicity of halloysite nanotubes and multi-walled carbon nanotubes to endothelial cells in vitro and blood vessels in vivo.
Wu B, Jiang M, Liu X, Huang C, Gu Z, Cao Y
Nanotoxicology 2020 Oct;14(8):1017-1038
Nanotoxicology 2020 Oct;14(8):1017-1038
Sphingosine-1-phosphate promotes pulmonary artery smooth muscle cells proliferation by stimulating autophagy-mediated E-cadherin/CDH1 down-regulation.
Zhai C, Feng W, Shi W, Wang J, Zhang Q, Yan X, Wang Q, Li S, Liu L, Pan Y, Zhu Y, Chai L, Li C, Liu P, Chen Y, Li M
European journal of pharmacology 2020 Oct 5;884:173302
European journal of pharmacology 2020 Oct 5;884:173302
HIF-1α-Mediated Mitophagy Determines ZnO Nanoparticle-Induced Human Osteosarcoma Cell Death both In Vitro and In Vivo.
He G, Pan X, Liu X, Zhu Y, Ma Y, Du C, Liu X, Mao C
ACS applied materials & interfaces 2020 Oct 28;12(43):48296-48309
ACS applied materials & interfaces 2020 Oct 28;12(43):48296-48309
Phosphatase and Tensin Homolog (PTEN) of Japanese Flounder-Its Regulation by miRNA and Role in Autophagy, Apoptosis and Pathogen Infection.
Li W, Guan X, Sun L
International journal of molecular sciences 2020 Oct 19;21(20)
International journal of molecular sciences 2020 Oct 19;21(20)
Design, synthesis, and biological evaluation of 5-((8-methoxy-2-methylquinolin-4-yl)amino)-1H-indole-2-carbohydrazide derivatives as novel Nur77 modulators.
Li B, Yao J, Guo K, He F, Chen K, Lin Z, Liu S, Huang J, Wu Q, Fang M, Zeng J, Wu Z
European journal of medicinal chemistry 2020 Oct 15;204:112608
European journal of medicinal chemistry 2020 Oct 15;204:112608
N‑linoleyltyrosine protects PC12 cells against oxidative damage via autophagy: Possible involvement of CB1 receptor regulation.
Liu X, Wu Y, Zhou D, Xie Y, Zhou Y, Lu Y, Yang R, Liu S
International journal of molecular medicine 2020 Nov;46(5):1827-1837
International journal of molecular medicine 2020 Nov;46(5):1827-1837
Drp1-mediated mitochondrial fission induced autophagy attenuates cell apoptosis caused by 3-chlorpropane-1,2-diol in HEK293 cells.
Jin C, Zhong Y, Han J, Zhu J, Liu Q, Sun D, Xia X, Peng X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Nov;145:111740
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Nov;145:111740
Deficiency of microglial Hv1 channel is associated with activation of autophagic pathway and ROS production in LPC-induced demyelination mouse model.
Chen M, Yang LL, Hu ZW, Qin C, Zhou LQ, Duan YL, Bosco DB, Wu LJ, Zhan KB, Xu SB, Tian DS
Journal of neuroinflammation 2020 Nov 6;17(1):333
Journal of neuroinflammation 2020 Nov 6;17(1):333
Sesn2 attenuates the damage of endothelial progenitor cells induced by angiotensin II through regulating the Keap1/Nrf2 signal pathway.
Ding S, Ma N, Liu H, Tang M, Mei J
Aging 2020 Nov 24;12(24):25505-25527
Aging 2020 Nov 24;12(24):25505-25527
Ganoderic acid D induces synergistic autophagic cell death except for apoptosis in ESCC cells.
Shao CS, Zhou XH, Zheng XX, Huang Q
Journal of ethnopharmacology 2020 Nov 15;262:113213
Journal of ethnopharmacology 2020 Nov 15;262:113213
Targeted inhibition of GRP78 by HA15 promotes apoptosis of lung cancer cells accompanied by ER stress and autophagy.
Wu J, Wu Y, Lian X
Biology open 2020 Nov 12;9(11)
Biology open 2020 Nov 12;9(11)
Acupuncture protects against cerebral ischemia-reperfusion injury via suppressing endoplasmic reticulum stress-mediated autophagy and apoptosis.
Sun X, Liu H, Sun Z, Zhang B, Wang X, Liu T, Pan T, Gao Y, Jiang X, Li H
Molecular medicine (Cambridge, Mass.) 2020 Nov 10;26(1):105
Molecular medicine (Cambridge, Mass.) 2020 Nov 10;26(1):105
TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis.
Xu S, Mao Y, Wu J, Feng J, Li J, Wu L, Yu Q, Zhou Y, Zhang J, Chen J, Ji J, Chen K, Wang F, Dai W, Fan X, Guo C
Journal of cellular and molecular medicine 2020 May;24(9):5224-5237
Journal of cellular and molecular medicine 2020 May;24(9):5224-5237
Astragaloside IV enhances GATA-4 mediated myocardial protection effect in hypoxia/reoxygenation injured H9c2 cells.
Yang JJ, Zhang XH, Ma XH, Duan WJ, Xu NG, Chen YJ, Liang L
Nutrition, metabolism, and cardiovascular diseases : NMCD 2020 May 7;30(5):829-842
Nutrition, metabolism, and cardiovascular diseases : NMCD 2020 May 7;30(5):829-842
miR-384-5p promotes spinal cord injury recovery in rats through suppressing of autophagy and endoplasmic reticulum stress.
Zhou Z, Hu B, Lyu Q, Xie T, Wang J, Cai Q
Neuroscience letters 2020 May 14;727:134937
Neuroscience letters 2020 May 14;727:134937
Inhibiting PKCβ2 protects HK-2 cells against meglumine diatrizoate and AGEs-induced apoptosis and autophagy.
Jiang W, Zhao W, Ye F, Huang S, Wu Y, Chen H, Zhou R, Fu G
Annals of translational medicine 2020 Mar;8(6):293
Annals of translational medicine 2020 Mar;8(6):293
A20 inhibits osteoclastogenesis via TRAF6-dependent autophagy in human periodontal ligament cells under hypoxia.
Yan K, Wu C, Ye Y, Li L, Wang X, He W, Ren S, Xu Y
Cell proliferation 2020 Mar;53(3):e12778
Cell proliferation 2020 Mar;53(3):e12778
MiRNA-211 triggers an autophagy-dependent apoptosis in cervical cancer cells: regulation of Bcl-2.
Liu S, Wang H, Mu J, Wang H, Peng Y, Li Q, Mao D, Guo L
Naunyn-Schmiedeberg's archives of pharmacology 2020 Mar;393(3):359-370
Naunyn-Schmiedeberg's archives of pharmacology 2020 Mar;393(3):359-370
CCN1 triggers adaptive autophagy in cardiomyocytes to curb its apoptotic activities.
Su BC, Hsu PL, Mo FE
Journal of cell communication and signaling 2020 Mar;14(1):93-100
Journal of cell communication and signaling 2020 Mar;14(1):93-100
Mainstream cigarette smoke induces autophagy and promotes apoptosis in oral mucosal epithelial cells.
Liu Q, Zhao M, Chen W, Xu K, Huang F, Qu J, Xu Z, Wang X, Wang Y, Zhu Y, Wang W
Archives of oral biology 2020 Mar;111:104646
Archives of oral biology 2020 Mar;111:104646
Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide.
Feng J, Zhang Y, Ren X, Li D, Fu H, Liu C, Zhou W, Liu Q, Liu Q, Wu M
Oncogene 2020 Jun;39(23):4551-4566
Oncogene 2020 Jun;39(23):4551-4566
Trehalose reduces bone loss in experimental biliary cirrhosis rats via ERK phosphorylation regulation by enhancing autophagosome formation.
Xu X, Wang R, Wu R, Yan W, Shi T, Jiang Q, Shi D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):8402-8415
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):8402-8415
Arsenic induces dysfunctional autophagy via dual regulation of mTOR pathway and Beclin1-Vps34/PI3K complex in MLTC-1 cells.
Liang C, Feng Z, Manthari RK, Wang C, Han Y, Fu W, Wang J, Zhang J
Journal of hazardous materials 2020 Jun 5;391:122227
Journal of hazardous materials 2020 Jun 5;391:122227
The RBP1-CKAP4 axis activates oncogenic autophagy and promotes cancer progression in oral squamous cell carcinoma.
Gao L, Wang Q, Ren W, Zheng J, Li S, Dou Z, Kong X, Liang X, Zhi K
Cell death & disease 2020 Jun 25;11(6):488
Cell death & disease 2020 Jun 25;11(6):488
Cafestol preconditioning attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting ERK/PPARγ pathway.
Ji J, Wu L, Feng J, Mo W, Wu J, Yu Q, Li S, Zhang J, Dai W, Xu X, Mao Y, Xu S, Chen K, Li J, Guo C
International immunopharmacology 2020 Jul;84:106529
International immunopharmacology 2020 Jul;84:106529
The Effect of Autophagic Activity on the Function of Apheresis Platelets and on the Efficacy of Clinical Platelet Transfusion.
Tang H, Gao M, Fu Y, Gui R, Ma X
Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie 2020 Jul;47(4):302-313
Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie 2020 Jul;47(4):302-313
GL-V9 reverses adriamycin resistance in hepatocellular carcinoma cells by affecting JNK2-related autophagy.
Yang Y, Liao Y, Gui YP, Zhao L, Guo LB
Chinese journal of natural medicines 2020 Jul;18(7):491-499
Chinese journal of natural medicines 2020 Jul;18(7):491-499
Tetrahydroxy stilbene glycoside alleviated inflammatory damage by mitophagy via AMPK related PINK1/Parkin signaling pathway.
Gao Y, Li J, Li J, Hu C, Zhang L, Yan J, Li L, Zhang L
Biochemical pharmacology 2020 Jul;177:113997
Biochemical pharmacology 2020 Jul;177:113997
LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes.
Zhou C, Yi C, Yi Y, Qin W, Yan Y, Dong X, Zhang X, Huang Y, Zhang R, Wei J, Ali DW, Michalak M, Chen XZ, Tang J
Molecular cancer 2020 Jul 29;19(1):118
Molecular cancer 2020 Jul 29;19(1):118
PRDX2 removal inhibits the cell cycle and autophagy in colorectal cancer cells.
Zheng X, Wei J, Li W, Li X, Wang W, Guo J, Fu Z
Aging 2020 Jul 20;12(16):16390-16409
Aging 2020 Jul 20;12(16):16390-16409
Melatonin alleviates defects induced by zearalenone during porcine embryo development.
Yao X, Jiang H, Gao Q, Li YH, Xu YN, Kim NH
Theriogenology 2020 Jul 15;151:66-73
Theriogenology 2020 Jul 15;151:66-73
14-3-3ζ binds to and stabilizes phospho-beclin 1S295 and induces autophagy in hepatocellular carcinoma cells.
Tang Y, Zhang Y, Liu S, Sun Z, Wang C, Li L, Zhou W, Cheng S
Journal of cellular and molecular medicine 2020 Jan;24(1):954-964
Journal of cellular and molecular medicine 2020 Jan;24(1):954-964
Targeting the WEE1 kinase strengthens the antitumor activity of imatinib via promoting KIT autophagic degradation in gastrointestinal stromal tumors.
Liu W, Zeng X, Yin Y, Li C, Yang W, Wan W, Shi L, Wang G, Tao K, Zhang P
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2020 Jan;23(1):39-51
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2020 Jan;23(1):39-51
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
Ma J, Qi J, Li S, Zhang C, Wang H, Shao L, Yuan X, Sha Q
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
The Preparation of Ginsenoside Rg5, Its Antitumor Activity against Breast Cancer Cells and Its Targeting of PI3K.
Liu Y, Fan D
Nutrients 2020 Jan 18;12(1)
Nutrients 2020 Jan 18;12(1)
NLRP3 inflammasome negatively regulates podocyte autophagy in diabetic nephropathy.
Hou Y, Lin S, Qiu J, Sun W, Dong M, Xiang Y, Wang L, Du P
Biochemical and biophysical research communications 2020 Jan 15;521(3):791-798
Biochemical and biophysical research communications 2020 Jan 15;521(3):791-798
Activation of cannabinoid receptor type 2-induced osteogenic differentiation involves autophagy induction and p62-mediated Nrf2 deactivation.
Xu A, Yang Y, Shao Y, Wu M, Sun Y
Cell communication and signaling : CCS 2020 Jan 15;18(1):9
Cell communication and signaling : CCS 2020 Jan 15;18(1):9
Autophagy Promotes Duck Tembusu Virus Replication by Suppressing p62/SQSTM1-Mediated Innate Immune Responses In Vitro.
Hu Z, Pan Y, Cheng A, Zhang X, Wang M, Chen S, Zhu D, Liu M, Yang Q, Wu Y, Zhao X, Huang J, Zhang S, Mao S, Ou X, Yu Y, Zhang L, Liu Y, Tian B, Pan L, Rehman MU, Yin Z, Jia R
Vaccines 2020 Jan 13;8(1)
Vaccines 2020 Jan 13;8(1)
Regular Aerobic Exercise-Alleviated Dysregulation of CAMKIIα Carbonylation to Mitigate Parkinsonism via Homeostasis of Apoptosis With Autophagy.
Liu W, Fu R, Wang Z, Liu S, Tang C, Li L, Yin D
Journal of neuropathology and experimental neurology 2020 Jan 1;79(1):46-61
Journal of neuropathology and experimental neurology 2020 Jan 1;79(1):46-61
MCP-1 mediates ischemia-reperfusion-induced cardiomyocyte apoptosis via MCPIP1 and CaSR.
Zhang W, Zhu T, Chen L, Luo W, Chao J
American journal of physiology. Heart and circulatory physiology 2020 Jan 1;318(1):H59-H71
American journal of physiology. Heart and circulatory physiology 2020 Jan 1;318(1):H59-H71
Ginsenoside Rb1 Alleviates Oxidative Low-Density Lipoprotein-Induced Vascular Endothelium Senescence via the SIRT1/Beclin-1/Autophagy Axis.
Shi G, Liu D, Zhou B, Liu Y, Hao B, Yu S, Wu L, Wang M, Song Z, Wu C, Zhu J, Qian X
Journal of cardiovascular pharmacology 2020 Feb;75(2):155-167
Journal of cardiovascular pharmacology 2020 Feb;75(2):155-167
CB2R orchestrates neuronal autophagy through regulation of the mTOR signaling pathway in the hippocampus of developing rats with status epilepticus.
Wu Q, Zhang M, Liu X, Zhang J, Wang H
International journal of molecular medicine 2020 Feb;45(2):475-484
International journal of molecular medicine 2020 Feb;45(2):475-484
Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea.
Xia B, Yu J, He T, Liu X, Su J, Wang M, Wang J, Zhu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2821-2839
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2821-2839
1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway.
Zhou Y, Fu X, Guan Y, Gong M, He K, Huang B
Biochemical pharmacology 2020 Feb;172:113752
Biochemical pharmacology 2020 Feb;172:113752
High mobility group box 1 antibody represses autophagy and alleviates hippocampus damage in pilocarpine-induced mouse epilepsy model.
Ying C, Ying L, Yanxia L, Le W, Lili C
Acta histochemica 2020 Feb;122(2):151485
Acta histochemica 2020 Feb;122(2):151485
MiRNA-192-5p attenuates airway remodeling and autophagy in asthma by targeting MMP-16 and ATG7.
Lou L, Tian M, Chang J, Li F, Zhang G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Feb;122:109692
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Feb;122:109692
Japanese flounder pol-miR-3p-2 suppresses Edwardsiella tarda infection by regulation of autophagy via p53.
Guan XL, Zhang BC, Sun L
Developmental and comparative immunology 2020 Feb;103:103531
Developmental and comparative immunology 2020 Feb;103:103531
Treadmill exercise improves neurological function by inhibiting autophagy and the binding of HMGB1 to Beclin1 in MCAO juvenile rats.
Pan G, Jin L, Shen W, Zhang J, Pan J, Cheng J, Xie Q, Hu Q, Wu S, Zhang H, Chen X
Life sciences 2020 Feb 15;243:117279
Life sciences 2020 Feb 15;243:117279
Protective effect of hydrogen sulfide on endothelial cells through Sirt1-FoxO1-mediated autophagy.
Zhu L, Duan W, Wu G, Zhang D, Wang L, Chen D, Chen Z, Yang B
Annals of translational medicine 2020 Dec;8(23):1586
Annals of translational medicine 2020 Dec;8(23):1586
Simvastatin protects high glucose-induced H9c2 cells from injury by inducing autophagy.
E L, Jiang H
Pharmaceutical biology 2020 Dec;58(1):1077-1084
Pharmaceutical biology 2020 Dec;58(1):1077-1084
Exogenous CGRP Regulates Apoptosis and Autophagy to Alleviate Traumatic Brain Injury Through Akt/mTOR Signalling Pathway.
Tian J, Yang L, Wang P, Yang L, Fan Z
Neurochemical research 2020 Dec;45(12):2926-2938
Neurochemical research 2020 Dec;45(12):2926-2938
Disruption of the Keap1/Nrf2-Antioxidant Response System After Chronic Doxorubicin Exposure In Vivo.
Nordgren KKS, Wallace KB
Cardiovascular toxicology 2020 Dec;20(6):557-570
Cardiovascular toxicology 2020 Dec;20(6):557-570
Pseudolaric acid B induces apoptosis in human rhabdomyosarcoma RD cells.
Liu C, Wang F, Wang B, Wu T, Wang Y, Huo W, Zhang S, Su Y, Liu J, Liu Y, Yu J
Oncology letters 2020 Dec;20(6):358
Oncology letters 2020 Dec;20(6):358
Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction.
Li Y, Liu M, Yi J, Song X, Zheng X, Liu D, Wang S, Chu C, Yang J
Acta biochimica et biophysica Sinica 2020 Dec 29;52(12):1325-1336
Acta biochimica et biophysica Sinica 2020 Dec 29;52(12):1325-1336
Intra-Articular Injection of (-)-Epigallocatechin 3-Gallate to Attenuate Articular Cartilage Degeneration by Enhancing Autophagy in a Post-Traumatic Osteoarthritis Rat Model.
Huang HT, Cheng TL, Ho CJ, Huang HH, Lu CC, Chuang SC, Li JY, Lee TC, Chen ST, Lin YS, Lee CY, Kang L, Lin SY, Chen CH
Antioxidants (Basel, Switzerland) 2020 Dec 23;10(1)
Antioxidants (Basel, Switzerland) 2020 Dec 23;10(1)
Regulation of FN1 degradation by the p62/SQSTM1-dependent autophagy-lysosome pathway in HNSCC.
Liu X, Meng L, Li X, Li D, Liu Q, Chen Y, Li X, Bu W, Sun H
International journal of oral science 2020 Dec 14;12(1):34
International journal of oral science 2020 Dec 14;12(1):34
Inhibition of autophagy enhances cadmium-induced apoptosis in duck renal tubular epithelial cells.
Wang C, Nie G, Zhuang Y, Hu R, Wu H, Xing C, Li G, Hu G, Yang F, Zhang C
Ecotoxicology and environmental safety 2020 Dec 1;205:111188
Ecotoxicology and environmental safety 2020 Dec 1;205:111188
Combined toxic effects of CBNPs and Pb on rat alveolar macrophage apoptosis and autophagy flux.
Guan S, Tao S, Huang Y, Jin Y, Hu Y, Lu J
Ecotoxicology and environmental safety 2020 Dec 1;205:111062
Ecotoxicology and environmental safety 2020 Dec 1;205:111062
The protective effects of pretreatment with resveratrol in cyclophosphamide-induced rat ovarian granulosa cell injury: In vitro study.
Nie Z, Zhang L, Chen W, Zhang Y, Hua R, Wang W, Zhang T, Wu H
Reproductive toxicology (Elmsford, N.Y.) 2020 Aug;95:66-74
Reproductive toxicology (Elmsford, N.Y.) 2020 Aug;95:66-74
S100A8 transported by SEC23A inhibits metastatic colonization via autocrine activation of autophagy.
Sun Z, Zeng B, Liu D, Zhao Q, Wang J, Rosie Xing H
Cell death & disease 2020 Aug 6;11(8):650
Cell death & disease 2020 Aug 6;11(8):650
Butyrate-mediated autophagy inhibition limits cytosolic Salmonella Infantis replication in the colon of pigs treated with a mixture of Lactobacillus and Bacillus.
Chu B, Zhu Y, Su J, Xia B, Zou Y, Nie J, Zhang W, Wang J
Veterinary research 2020 Aug 5;51(1):99
Veterinary research 2020 Aug 5;51(1):99
RND2 attenuates apoptosis and autophagy in glioblastoma cells by targeting the p38 MAPK signalling pathway.
Xu Y, Sun Q, Yuan F, Dong H, Zhang H, Geng R, Qi Y, Xiong X, Chen Q, Liu B
Journal of experimental & clinical cancer research : CR 2020 Aug 31;39(1):174
Journal of experimental & clinical cancer research : CR 2020 Aug 31;39(1):174
Suppressing endoplasmic reticulum stress-related autophagy attenuates retinal light injury.
Song JY, Fan B, Che L, Pan YR, Zhang SM, Wang Y, Bunik V, Li GY
Aging 2020 Aug 28;12(16):16579-16596
Aging 2020 Aug 28;12(16):16579-16596
N6-(2-hydroxyethyl)-Adenosine Induces Apoptosis via ER Stress and Autophagy of Gastric Carcinoma Cells In Vitro and In Vivo.
Xie H, Li X, Yang W, Yu L, Jiang X, Chen Y, Shen Z, Li C, Gu M, Shi L
International journal of molecular sciences 2020 Aug 13;21(16)
International journal of molecular sciences 2020 Aug 13;21(16)
Protective Effect of Purple Tomato Anthocyanidin on Chromium(VI)-Induced Autophagy in LMH Cells by Inhibiting Endoplasmic Reticulum Stress.
Liu K, Chen P, Lu J, Zhu Y, Xu Y, Liu Y, Liu J
Biological trace element research 2020 Apr;194(2):570-580
Biological trace element research 2020 Apr;194(2):570-580
Hydroxysafflor yellow A induces autophagy in human liver cancer cells by regulating Beclin 1 and ERK expression.
Chen Z, Liu L, Liu Y, Wang S, Zhang S, Dong R, Xu M, Ma Y, Wang J, Zhang Q, Wei P
Experimental and therapeutic medicine 2020 Apr;19(4):2989-2996
Experimental and therapeutic medicine 2020 Apr;19(4):2989-2996
Exogenous H2S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice.
Sun Y, Lu F, Yu X, Wang B, Chen J, Lu F, Peng S, Sun X, Yu M, Chen H, Wang Y, Zhang L, Liu N, Du H, Zhao D, Zhang W
Aging and disease 2020 Apr;11(2):269-285
Aging and disease 2020 Apr;11(2):269-285
Exosomes derived from mesenchymal stem cells repair a Parkinson's disease model by inducing autophagy.
Chen HX, Liang FC, Gu P, Xu BL, Xu HJ, Wang WT, Hou JY, Xie DX, Chai XQ, An SJ
Cell death & disease 2020 Apr 27;11(4):288
Cell death & disease 2020 Apr 27;11(4):288
CACNA1H downregulation induces skeletal muscle atrophy involving endoplasmic reticulum stress activation and autophagy flux blockade.
Li S, Hao M, Li B, Chen M, Chen J, Tang J, Hong S, Min J, Hu M, Hong L
Cell death & disease 2020 Apr 24;11(4):279
Cell death & disease 2020 Apr 24;11(4):279
Critical role of Tim-3 mediated autophagy in chronic stress induced immunosuppression.
Qin A, Zhong T, Zou H, Wan X, Yao B, Zheng X, Yin D
Cell & bioscience 2019;9:13
Cell & bioscience 2019;9:13
Isorhamnetin Inhibits Liver Fibrosis by Reducing Autophagy and Inhibiting Extracellular Matrix Formation via the TGF-β1/Smad3 and TGF-β1/p38 MAPK Pathways.
Liu N, Feng J, Lu X, Yao Z, Liu Q, Lv Y, Han Y, Deng J, Zhou Y
Mediators of inflammation 2019;2019:6175091
Mediators of inflammation 2019;2019:6175091
Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy.
Wang W, Wu L, Li J, Ji J, Chen K, Yu Q, Li S, Feng J, Liu T, Zhang J, Chen J, Zhou Y, Mao Y, Wang F, Dai W, Fan X, Guo C, Wu J
Mediators of inflammation 2019;2019:3240713
Mediators of inflammation 2019;2019:3240713
Enhanced p62-NRF2 Feedback Loop due to Impaired Autophagic Flux Contributes to Arsenic-Induced Malignant Transformation of Human Keratinocytes.
Wu X, Sun R, Wang H, Yang B, Wang F, Xu H, Chen S, Zhao R, Pi J, Xu Y
Oxidative medicine and cellular longevity 2019;2019:1038932
Oxidative medicine and cellular longevity 2019;2019:1038932
Gambogic acid induces autophagy and combines synergistically with chloroquine to suppress pancreatic cancer by increasing the accumulation of reactive oxygen species.
Wang H, Zhao Z, Lei S, Li S, Xiang Z, Wang X, Huang X, Xia G, Huang X
Cancer cell international 2019;19:7
Cancer cell international 2019;19:7
FePt/GO Nanosheets Suppress Proliferation, Enhance Radiosensitization and Induce Autophagy of Human Non-Small Cell Lung Cancer Cells.
Ma S, Miao H, Luo Y, Sun Y, Tian X, Wang F, You C, Peng S, Tang G, Yang C, Sun W, Li S, Mao Y, Xu J, Xiao Y, Gong Y, Quan H, Xie C
International journal of biological sciences 2019;15(5):999-1009
International journal of biological sciences 2019;15(5):999-1009
The ginsenoside Rk3 exerts anti-esophageal cancer activity in vitro and in vivo by mediating apoptosis and autophagy through regulation of the PI3K/Akt/mTOR pathway.
Liu H, Zhao J, Fu R, Zhu C, Fan D
PloS one 2019;14(5):e0216759
PloS one 2019;14(5):e0216759
LAPTM4B knockdown increases the radiosensitivity of EGFR-overexpressing radioresistant nasopharyngeal cancer cells by inhibiting autophagy.
Chu C, Niu X, Ou X, Hu C
OncoTargets and therapy 2019;12:5661-5677
OncoTargets and therapy 2019;12:5661-5677
Glycyrrhizic acid ameliorates LPS-induced acute lung injury by regulating autophagy through the PI3K/AKT/mTOR pathway.
Qu L, Chen C, He W, Chen Y, Li Y, Wen Y, Zhou S, Jiang Y, Yang X, Zhang R, Shen L
American journal of translational research 2019;11(4):2042-2055
American journal of translational research 2019;11(4):2042-2055
Diosbulbin B-Induced Mitochondria-Dependent Apoptosis in L-02 Hepatocytes is Regulated by Reactive Oxygen Species-Mediated Autophagy.
Ye J, Xue M, Liu Y, Zhu S, Li Y, Liu X, Cai D, Rui J, Zhang L
Frontiers in pharmacology 2019;10:676
Frontiers in pharmacology 2019;10:676
The Anti-proliferative Activity of GnRH Through Downregulation of the Akt/ERK Pathways in Pancreatic Cancer.
Suo L, Chang X, Xu N, Ji H
Frontiers in endocrinology 2019;10:370
Frontiers in endocrinology 2019;10:370
IL-17A-Mediated Excessive Autophagy Aggravated Neuronal Ischemic Injuries via Src-PP2B-mTOR Pathway.
Liu T, Han S, Dai Q, Zheng J, Liu C, Li S, Li J
Frontiers in immunology 2019;10:2952
Frontiers in immunology 2019;10:2952
Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux.
Wang D, Guo H, Yang H, Wang D, Gao P, Wei W
Frontiers in pharmacology 2019;10:1238
Frontiers in pharmacology 2019;10:1238
The balance of apoptosis and autophagy via regulation of the AMPK signal pathway in aging rat striatum during regular aerobic exercise.
Liu W, Wang Z, Xia Y, Kuang H, Liu S, Li L, Tang C, Yin D
Experimental gerontology 2019 Sep;124:110647
Experimental gerontology 2019 Sep;124:110647
Corticosterone Excess-Mediated Mitochondrial Damage Induces Hippocampal Neuronal Autophagy in Mice Following Cold Exposure.
Xu B, Lang L, Li S, Yuan J, Wang J, Yang H, Lian S
Animals : an open access journal from MDPI 2019 Sep 14;9(9)
Animals : an open access journal from MDPI 2019 Sep 14;9(9)
Hippocampus Metabolic Disturbance and Autophagy Deficiency in Olfactory Bulbectomized Rats and the Modulatory Effect of Fluoxetine.
Zhou Y, Tao X, Wang Z, Feng L, Wang L, Liu X, Pan R, Liao Y, Chang Q
International journal of molecular sciences 2019 Sep 1;20(17)
International journal of molecular sciences 2019 Sep 1;20(17)
PGC-1α acts as an mediator of Sirtuin2 to protect annulus fibrosus from apoptosis induced by oxidative stress through restraining mitophagy.
Xu WN, Yang RZ, Zheng HL, Yu W, Zheng XF, Li B, Jiang SD, Jiang LS
International journal of biological macromolecules 2019 Sep 1;136:1007-1017
International journal of biological macromolecules 2019 Sep 1;136:1007-1017
Orientin Improves Cognition by Enhancing Autophagosome Clearance in an Alzheimer's Mouse Model.
Zhong Y, Zheng QY, Sun CY, Zhang Z, Han K, Jia N
Journal of molecular neuroscience : MN 2019 Oct;69(2):246-253
Journal of molecular neuroscience : MN 2019 Oct;69(2):246-253
Chrysophanol attenuates airway inflammation and remodeling through nuclear factor-kappa B signaling pathway in asthma.
Song G, Zhang Y, Yu S, Lv W, Guan Z, Sun M, Wang J
Phytotherapy research : PTR 2019 Oct;33(10):2702-2713
Phytotherapy research : PTR 2019 Oct;33(10):2702-2713
Inhibited autophagy impairs systemic nutrient metabolism in Nile tilapia.
Han SL, Wang J, Zhang YX, Qiao F, Chen LQ, Zhang ML, Du ZY
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2019 Oct;236:110521
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2019 Oct;236:110521
Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer.
Liu Y, Fan D
Biochemical pharmacology 2019 Oct;168:285-304
Biochemical pharmacology 2019 Oct;168:285-304
Neuroprotective effect of Verbascoside on hypoxic-ischemic brain damage in neonatal rat.
Wei W, Lu M, Lan X, Liu N, Wang H, Du J, Sun T, Li Y, Yu J
Neuroscience letters 2019 Oct 15;711:134415
Neuroscience letters 2019 Oct 15;711:134415
Quetiapine induces myocardial necroptotic cell death through bidirectional regulation of cannabinoid receptors.
Li X, Peng Z, Zhou Y, Wang J, Lin X, Dong X, Liu X, Jiang J, Jiang Y, Li L
Toxicology letters 2019 Oct 1;313:77-90
Toxicology letters 2019 Oct 1;313:77-90
The roles of Nrf2 and autophagy in modulating inflammation mediated by TLR4 - NFκB in A549 cell exposed to layer house particulate matter 2.5 (PM2.5).
Dai P, Shen D, Shen J, Tang Q, Xi M, Li Y, Li C
Chemosphere 2019 Nov;235:1134-1145
Chemosphere 2019 Nov;235:1134-1145
Iron dysregulation in vascular dementia: Focused on the AMPK/autophagy pathway.
Huo T, Jia Y, Yin C, Luo X, Zhao J, Wang Z, Lv P
Brain research bulletin 2019 Nov;153:305-313
Brain research bulletin 2019 Nov;153:305-313
Emodin reactivated autophagy and alleviated inflammatory lung injury in mice with lethal endotoxemia.
Dong Y, Zhang L, Jiang Y, Dai J, Tang L, Liu G
Experimental animals 2019 Nov 6;68(4):559-568
Experimental animals 2019 Nov 6;68(4):559-568
Downregulation of microRNA-30a-5p contributes to the replication of duck enteritis virus by regulating Beclin-1-mediated autophagy.
Wu X, Jia R, Wang M, Chen S, Liu M, Zhu D, Zhao X, Yang Q, Wu Y, Yin Z, Zhang S, Huang J, Zhang L, Liu Y, Yu Y, Pan L, Tian B, Rehman MU, Chen X, Cheng A
Virology journal 2019 Nov 26;16(1):144
Virology journal 2019 Nov 26;16(1):144
Beclin1-mediated ferroptosis activation is associated with isoflurane-induced toxicity in SH-SY5Y neuroblastoma cells.
Liu R, Li X, Zhao G
Acta biochimica et biophysica Sinica 2019 Nov 18;51(11):1134-1141
Acta biochimica et biophysica Sinica 2019 Nov 18;51(11):1134-1141
Mitochondrial NDUFA4L2 attenuates the apoptosis of nucleus pulposus cells induced by oxidative stress via the inhibition of mitophagy.
Xu WN, Zheng HL, Yang RZ, Liu T, Yu W, Zheng XF, Li B, Jiang SD, Jiang LS
Experimental & molecular medicine 2019 Nov 18;51(11):1-16
Experimental & molecular medicine 2019 Nov 18;51(11):1-16
A novel ALK inhibitor ZYY inhibits Karpas299 cell growth in vitro and in a mouse xenograft model and induces protective autophagy.
Shen J, Wang J, Du J, Wang L, Zhou X, Chang X, Li Z, Zhai X, Zuo D, Wu Y
Toxicology and applied pharmacology 2019 Nov 15;383:114781
Toxicology and applied pharmacology 2019 Nov 15;383:114781
Punicalagin Prevents Inflammation in LPS-Induced RAW264.7 Macrophages by Inhibiting FoxO3a/Autophagy Signaling Pathway.
Cao Y, Chen J, Ren G, Zhang Y, Tan X, Yang L
Nutrients 2019 Nov 15;11(11)
Nutrients 2019 Nov 15;11(11)
Protective effects of levo-tetrahydropalmatine on hepatic ischemia/reperfusion injury are mediated by inhibition of the ERK/NF-κB pathway.
Yu Q, Wu L, Liu T, Li S, Feng J, Mao Y, Fan X, Guo C, Wu J
International immunopharmacology 2019 May;70:435-445
International immunopharmacology 2019 May;70:435-445
α-hederin induces autophagic cell death in colorectal cancer cells through reactive oxygen species dependent AMPK/mTOR signaling pathway activation.
Sun J, Feng Y, Wang Y, Ji Q, Cai G, Shi L, Wang Y, Huang Y, Zhang J, Li Q
International journal of oncology 2019 May;54(5):1601-1612
International journal of oncology 2019 May;54(5):1601-1612
Paclitaxel alleviates monocrotaline-induced pulmonary arterial hypertension via inhibition of FoxO1-mediated autophagy.
Feng W, Wang J, Yan X, Zhai C, Shi W, Wang Q, Zhang Q, Li M
Naunyn-Schmiedeberg's archives of pharmacology 2019 May;392(5):605-613
Naunyn-Schmiedeberg's archives of pharmacology 2019 May;392(5):605-613
Kallikrein 12 Regulates Innate Resistance of Murine Macrophages against Mycobacterium bovis Infection by Modulating Autophagy and Apoptosis.
Sabir N, Hussain T, Liao Y, Wang J, Song Y, Shahid M, Cheng G, Mangi MH, Yao J, Yang L, Zhao D, Zhou X
Cells 2019 May 5;8(5)
Cells 2019 May 5;8(5)
The Glycoprotein and Nucleocapsid Protein of Hantaviruses Manipulate Autophagy Flux to Restrain Host Innate Immune Responses.
Wang K, Ma H, Liu H, Ye W, Li Z, Cheng L, Zhang L, Lei Y, Shen L, Zhang F
Cell reports 2019 May 14;27(7):2075-2091.e5
Cell reports 2019 May 14;27(7):2075-2091.e5
The preoperative neutrophil-to-lymphocyte ratio is not a marker of prostate cancer characteristics but is an independent predictor of biochemical recurrence in patients receiving radical prostatectomy.
Cao Z, Ji J, Zhang C, Wang F, Xu H, Yu Y, Sun Y
Cancer medicine 2019 Mar;8(3):1004-1012
Cancer medicine 2019 Mar;8(3):1004-1012
Fasting enhances cold resistance in fish through stimulating lipid catabolism and autophagy.
Lu DL, Ma Q, Wang J, Li LY, Han SL, Limbu SM, Li DL, Chen LQ, Zhang ML, Du ZY
The Journal of physiology 2019 Mar;597(6):1585-1603
The Journal of physiology 2019 Mar;597(6):1585-1603
Pb disrupts autophagic flux through inhibiting the formation and activity of lysosomes in neural cells.
Gu X, Han M, Du Y, Wu Y, Xu Y, Zhou X, Ye D, Wang HL
Toxicology in vitro : an international journal published in association with BIBRA 2019 Mar;55:43-50
Toxicology in vitro : an international journal published in association with BIBRA 2019 Mar;55:43-50
Fibroblast growth factor-21 alleviates hypoxia/reoxygenation injury in H9c2 cardiomyocytes by promoting autophagic flux.
Ren Z, Xiao W, Zeng Y, Liu MH, Li GH, Tang ZH, Qu SL, Hao YM, Yuan HQ, Jiang ZS
International journal of molecular medicine 2019 Mar;43(3):1321-1330
International journal of molecular medicine 2019 Mar;43(3):1321-1330
CERKL regulates autophagy via the NAD-dependent deacetylase SIRT1.
Hu X, Lu Z, Yu S, Reilly J, Liu F, Jia D, Qin Y, Han S, Liu X, Qu Z, Lv Y, Li J, Huang Y, Jiang T, Jia H, Wang Q, Liu J, Shu X, Tang Z, Liu M
Autophagy 2019 Mar;15(3):453-465
Autophagy 2019 Mar;15(3):453-465
Osteosarcoma cell intrinsic PD-L2 signals promote invasion and metastasis via the RhoA-ROCK-LIMK2 and autophagy pathways.
Ren T, Zheng B, Huang Y, Wang S, Bao X, Liu K, Guo W
Cell death & disease 2019 Mar 18;10(4):261
Cell death & disease 2019 Mar 18;10(4):261
TLR2 promotes development and progression of human glioma via enhancing autophagy.
Li C, Ma L, Liu Y, Li Z, Wang Q, Chen Z, Geng X, Han X, Sun J, Li Z
Gene 2019 Jun 5;700:52-59
Gene 2019 Jun 5;700:52-59
The long non-coding RNA H19 induces hypoxia/reoxygenation injury by up-regulating autophagy in the hepatoma carcinoma cells.
Cui C, Li Z, Wu D
Biological research 2019 Jun 13;52(1):32
Biological research 2019 Jun 13;52(1):32
Mitochondrial dynamics modulation as a critical contribution for Shenmai injection in attenuating hypoxia/reoxygenation injury.
Yu J, Li Y, Liu X, Ma Z, Michael S, Orgah JO, Fan G, Zhu Y
Journal of ethnopharmacology 2019 Jun 12;237:9-19
Journal of ethnopharmacology 2019 Jun 12;237:9-19
Nonstructural Protein NP1 of Human Bocavirus 1 suppresses the growth of A549 cell by promoting autophagy.
Zhu J, Li J, Wang X, Feng X, Li Y
The new microbiologica 2019 Jul;42(3):161-165
The new microbiologica 2019 Jul;42(3):161-165
Bone marrow mesenchymal stem cells repair Cr (VI)- injured kidney by regulating mitochondria-mediated apoptosis and mitophagy mediated via the MAPK signaling pathway.
Yin F, Yan J, Zhao Y, Guo KJ, Zhang ZL, Li AP, Meng CY, Guo L
Ecotoxicology and environmental safety 2019 Jul 30;176:234-241
Ecotoxicology and environmental safety 2019 Jul 30;176:234-241
iRoot BP Plus promotes osteo/odontogenic differentiation of bone marrow mesenchymal stem cells via MAPK pathways and autophagy.
Lu J, Li Z, Wu X, Chen Y, Yan M, Ge X, Yu J
Stem cell research & therapy 2019 Jul 29;10(1):222
Stem cell research & therapy 2019 Jul 29;10(1):222
Polyethers isolated from the marine actinobacterium Streptomyces cacaoi inhibit autophagy and induce apoptosis in cancer cells.
Khan N, Yılmaz S, Aksoy S, Uzel A, Tosun Ç, Kirmizibayrak PB, Bedir E
Chemico-biological interactions 2019 Jul 1;307:167-178
Chemico-biological interactions 2019 Jul 1;307:167-178
Berberine ameliorates oxidative stress-induced apoptosis by modulating ER stress and autophagy in human nucleus pulposus cells.
Luo R, Liao Z, Song Y, Yin H, Zhan S, Li G, Ma L, Lu S, Wang K, Li S, Zhang Y, Yang C
Life sciences 2019 Jul 1;228:85-97
Life sciences 2019 Jul 1;228:85-97
Alleviation of hepatic fibrosis and autophagy via inhibition of transforming growth factor-β1/Smads pathway through shikonin.
Liu T, Xu L, Wang C, Chen K, Xia Y, Li J, Li S, Wu L, Feng J, Xu S, Wang W, Lu X, Fan X, Mo W, Zhou Y, Zhao Y, Guo C
Journal of gastroenterology and hepatology 2019 Jan;34(1):263-276
Journal of gastroenterology and hepatology 2019 Jan;34(1):263-276
The interaction of Atg4B and Bcl-2 plays an important role in Cd-induced crosstalk between apoptosis and autophagy through disassociation of Bcl-2-Beclin1 in A549 cells.
Li Z, Li Q, Lv W, Jiang L, Geng C, Yao X, Shi X, Liu Y, Cao J
Free radical biology & medicine 2019 Jan;130:576-591
Free radical biology & medicine 2019 Jan;130:576-591
Autophagy and Apoptosis Interact to Modulate T-2 Toxin-Induced Toxicity in Liver Cells.
Wu J, Zhou Y, Yuan Z, Yi J, Chen J, Wang N, Tian Y
Toxins 2019 Jan 15;11(1)
Toxins 2019 Jan 15;11(1)
Down-regulation of lncRNA OGFRP1 induces autophagy and growth inhibition by AKT/mTOR signaling pathway in HCAECs.
Zhang X, Liu J, Gu Y, Sun C, Qu F
Cell biology international 2019 Feb;43(2):158-166
Cell biology international 2019 Feb;43(2):158-166
α‑lipoic acid protects against carbon tetrachloride‑induced liver cirrhosis through the suppression of the TGF‑β/Smad3 pathway and autophagy.
Liu G, Liu J, Pian L, Gui S, Lu B
Molecular medicine reports 2019 Feb;19(2):841-850
Molecular medicine reports 2019 Feb;19(2):841-850
Effects of Fluoride on Autophagy in Mouse Sertoli Cells.
Feng Z, Liang C, Manthari RK, Wang C, Zhang J
Biological trace element research 2019 Feb;187(2):499-505
Biological trace element research 2019 Feb;187(2):499-505
Microglia as modulators of exosomal alpha-synuclein transmission.
Xia Y, Zhang G, Han C, Ma K, Guo X, Wan F, Kou L, Yin S, Liu L, Huang J, Xiong N, Wang T
Cell death & disease 2019 Feb 20;10(3):174
Cell death & disease 2019 Feb 20;10(3):174
Sodium fluoride regulates the osteo/odontogenic differentiation of stem cells from apical papilla by modulating autophagy.
Pan Y, Li Z, Wang Y, Yan M, Wu J, Beharee RG, Yu J
Journal of cellular physiology 2019 Feb 14;
Journal of cellular physiology 2019 Feb 14;
Icariin Ameliorates Amyloid Pathologies by Maintaining Homeostasis of Autophagic Systems in Aβ1-42-Injected Rats.
Jiang X, Chen LL, Lan Z, Xiong F, Xu X, Yin YY, Li P, Wang P
Neurochemical research 2019 Dec;44(12):2708-2722
Neurochemical research 2019 Dec;44(12):2708-2722
Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats.
Bian X, Bai Y, Su X, Zhao G, Sun G, Li D
Journal of cellular physiology 2019 Dec;234(12):22857-22873
Journal of cellular physiology 2019 Dec;234(12):22857-22873
Punicalagin Reversed the Hepatic Injury of Tetrachloromethane by Antioxidation and Enhancement of Autophagy.
Luo J, Long Y, Ren G, Zhang Y, Chen J, Huang R, Yang L
Journal of medicinal food 2019 Dec;22(12):1271-1279
Journal of medicinal food 2019 Dec;22(12):1271-1279
Sufentanil impairs autophagic degradation and inhibits cell migration in NCI-H460 in vitro.
Jiang H, Wang H, Zou W, Hu Y, Chen C, Wang C
Oncology letters 2019 Dec;18(6):6829-6835
Oncology letters 2019 Dec;18(6):6829-6835
Autophagy Attenuation Hampers Progesterone Synthesis during the Development of Pregnant Corpus Luteum.
Tang Z, Zhang Z, Zhang H, Wang Y, Zhang Y, Zhao J, Yang H, Wang Z
Cells 2019 Dec 27;9(1)
Cells 2019 Dec 27;9(1)
PD-L1 regulates tumorigenesis and autophagy of ovarian cancer by activating mTORC signaling.
Gao H, Zhang J, Ren X
Bioscience reports 2019 Dec 20;39(12)
Bioscience reports 2019 Dec 20;39(12)
Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis.
Huang X, Ni B, Xi Y, Chu X, Zhang R, You H
Aging 2019 Dec 16;11(24):12532-12545
Aging 2019 Dec 16;11(24):12532-12545
HMGB1/TLR4 promotes apoptosis and reduces autophagy of hippocampal neurons in diabetes combined with OSA.
Guo X, Shi Y, Du P, Wang J, Han Y, Sun B, Feng J
Life sciences 2019 Dec 15;239:117020
Life sciences 2019 Dec 15;239:117020
A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice.
Quach C, Song Y, Guo H, Li S, Maazi H, Fung M, Sands N, O'Connell D, Restrepo-Vassalli S, Chai B, Nemecio D, Punj V, Akbari O, Idos GE, Mumenthaler SM, Wu N, Martin SE, Hagiya A, Hicks J, Cui H, Liang C
Nature communications 2019 Dec 12;10(1):5681
Nature communications 2019 Dec 12;10(1):5681
Visfatin Plays a Significant Role in Alleviating Lipopolysaccharide-Induced Apoptosis and Autophagy Through PI3K/AKT Signaling Pathway During Acute Lung Injury in Mice.
Wu XT, Ansari AR, Pang XX, Li HZ, Zhang ZW, Luo Y, Arshad M, Song H
Archivum immunologiae et therapiae experimentalis 2019 Aug;67(4):249-261
Archivum immunologiae et therapiae experimentalis 2019 Aug;67(4):249-261
Nix/BNIP3L-dependent mitophagy accounts for airway epithelial cell injury induced by cigarette smoke.
Zhang M, Shi R, Zhang Y, Shan H, Zhang Q, Yang X, Li Y, Zhang J
Journal of cellular physiology 2019 Aug;234(8):14210-14220
Journal of cellular physiology 2019 Aug;234(8):14210-14220
Platelet-Membrane-Camouflaged Black Phosphorus Quantum Dots Enhance Anticancer Effect Mediated by Apoptosis and Autophagy.
Shang Y, Wang Q, Wu B, Zhao Q, Li J, Huang X, Chen W, Gui R
ACS applied materials & interfaces 2019 Aug 7;11(31):28254-28266
ACS applied materials & interfaces 2019 Aug 7;11(31):28254-28266
Role of Thymoquinone in Cardiac Damage Caused by Sepsis from BALB/c Mice.
Liu H, Sun Y, Zhang Y, Yang G, Guo L, Zhao Y, Pei Z
Inflammation 2019 Apr;42(2):516-525
Inflammation 2019 Apr;42(2):516-525
Autophagy induction and antiproliferative effect of a novel curcumin derivative MOMI-1 on the human lung cancer cells A549.
Zhou GZ, Shi YY, Wei LL, Sun GC
Journal of biochemical and molecular toxicology 2019 Apr;33(4):e22280
Journal of biochemical and molecular toxicology 2019 Apr;33(4):e22280
Potent effects of dioscin against hepatocellular carcinoma through regulating TP53-induced glycolysis and apoptosis regulator (TIGAR)-mediated apoptosis, autophagy, and DNA damage.
Mao Z, Han X, Chen D, Xu Y, Xu L, Yin L, Sun H, Qi Y, Fang L, Liu K, Peng J
British journal of pharmacology 2019 Apr;176(7):919-937
British journal of pharmacology 2019 Apr;176(7):919-937
Neuroprotective effects of rapamycin on spinal cord injury in rats by increasing autophagy and Akt signaling.
Li XG, Du JH, Lu Y, Lin XJ
Neural regeneration research 2019 Apr;14(4):721-727
Neural regeneration research 2019 Apr;14(4):721-727
Silver nanoparticles induce protective autophagy via Ca2+/CaMKKβ/AMPK/mTOR pathway in SH-SY5Y cells and rat brains.
Li L, Li L, Zhou X, Yu Y, Li Z, Zuo D, Wu Y
Nanotoxicology 2019 Apr;13(3):369-391
Nanotoxicology 2019 Apr;13(3):369-391
Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy.
Cai Q, Wang S, Jin L, Weng M, Zhou D, Wang J, Tang Z, Quan Z
Molecular cancer 2019 Apr 5;18(1):82
Molecular cancer 2019 Apr 5;18(1):82
Evaluating expression of autophagy-related genes in oriental river prawn Macrobrachium nipponense as potential biomarkers for hypoxia exposure.
Sun S, Wu Y, Fu H, Yang M, Ge X, Zhu J, Xuan F, Wu X
Ecotoxicology and environmental safety 2019 Apr 30;171:484-492
Ecotoxicology and environmental safety 2019 Apr 30;171:484-492
Autophagy exerts pivotal roles in regulatory effects of 1α,25-(OH)2D3 on the osteoclastogenesis.
Ji L, Gao J, Kong R, Gao Y, Ji X, Zhao D
Biochemical and biophysical research communications 2019 Apr 16;511(4):869-874
Biochemical and biophysical research communications 2019 Apr 16;511(4):869-874
Lysophosphatidic Acid Is Associated With Cardiac Dysfunction and Hypertrophy by Suppressing Autophagy via the LPA3/AKT/mTOR Pathway.
Yang J, Xu J, Han X, Wang H, Zhang Y, Dong J, Deng Y, Wang J
Frontiers in physiology 2018;9:1315
Frontiers in physiology 2018;9:1315
The Protective Effects of Levo-Tetrahydropalmatine on ConA-Induced Liver Injury Are via TRAF6/JNK Signaling.
Yu Q, Liu T, Li S, Feng J, Wu L, Wang W, Chen K, Xia Y, Niu P, Xu L, Wang F, Dai W, Zhou Y, Guo C
Mediators of inflammation 2018;2018:4032484
Mediators of inflammation 2018;2018:4032484
The Hepatoprotection by Oleanolic Acid Preconditioning: Focusing on PPARα Activation.
Wang W, Chen K, Xia Y, Mo W, Wang F, Dai W, Niu P
PPAR research 2018;2018:3180396
PPAR research 2018;2018:3180396
Fucosterol Protects against Concanavalin A-Induced Acute Liver Injury: Focus on P38 MAPK/NF-κB Pathway Activity.
Mo W, Wang C, Li J, Chen K, Xia Y, Li S, Xu L, Lu X, Wang W, Guo C
Gastroenterology research and practice 2018;2018:2824139
Gastroenterology research and practice 2018;2018:2824139
Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke.
Han B, Zhang Y, Zhang Y, Bai Y, Chen X, Huang R, Wu F, Leng S, Chao J, Zhang JH, Hu G, Yao H
Autophagy 2018;14(7):1164-1184
Autophagy 2018;14(7):1164-1184
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.
Yang L, Han B, Zhang Y, Bai Y, Chao J, Hu G, Yao H
Autophagy 2018;14(3):404-418
Autophagy 2018;14(3):404-418
TRIM59 regulates autophagy through modulating both the transcription and the ubiquitination of BECN1.
Han T, Guo M, Gan M, Yu B, Tian X, Wang JB
Autophagy 2018;14(12):2035-2048
Autophagy 2018;14(12):2035-2048
Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways.
Feng J, Chen K, Xia Y, Wu L, Li J, Li S, Wang W, Lu X, Liu T, Guo C
Drug design, development and therapy 2018;12:1837-1853
Drug design, development and therapy 2018;12:1837-1853
Apolipoprotein E-Mimetic Peptide COG1410 Promotes Autophagy by Phosphorylating GSK-3β in Early Brain Injury Following Experimental Subarachnoid Hemorrhage.
Li X, Peng J, Pang J, Wu Y, Huang X, Li Y, Zhou J, Gu L, Sun X, Chen L, Vitek MP, Jiang Y
Frontiers in neuroscience 2018;12:127
Frontiers in neuroscience 2018;12:127
Melatonin Regulates Apoptosis and Autophagy Via ROS-MST1 Pathway in Subarachnoid Hemorrhage.
Shi L, Liang F, Zheng J, Zhou K, Chen S, Yu J, Zhang J
Frontiers in molecular neuroscience 2018;11:93
Frontiers in molecular neuroscience 2018;11:93
High expression of TFEB is associated with aggressive clinical features in colorectal cancer.
Liang J, Jia X, Wang K, Zhao N
OncoTargets and therapy 2018;11:8089-8098
OncoTargets and therapy 2018;11:8089-8098
Human tissue kallikrein 1 ameliorates erectile function via modulation of macroautophagy in aged transgenic rats.
Tang Z, Cui K, Luan Y, Ruan Y, Wang T, Yang J, Wang S, Liu J, Wang D
Andrology 2018 Sep;6(5):766-774
Andrology 2018 Sep;6(5):766-774
Rapamycin Supplementation May Ameliorate Erectile Function in Rats With Streptozotocin-Induced Type 1 Diabetes by Inducing Autophagy and Inhibiting Apoptosis, Endothelial Dysfunction, and Corporal Fibrosis.
Lin H, Wang T, Ruan Y, Liu K, Li H, Wang S, Li M, Liu J
The journal of sexual medicine 2018 Sep;15(9):1246-1259
The journal of sexual medicine 2018 Sep;15(9):1246-1259
LP1 from Lentinula edodes C91-3 Induces Autophagy, Apoptosis and Reduces Metastasis in Human Gastric Cancer Cell Line SGC-7901.
Batool S, Joseph TP, Hussain M, Vuai MS, Khinsar KH, Din SRU, Padhiar AA, Zhong M, Ning A, Zhang W, Cao J, Huang M
International journal of molecular sciences 2018 Sep 30;19(10)
International journal of molecular sciences 2018 Sep 30;19(10)
Moderate hypothermia inhibits microglial activation after traumatic brain injury by modulating autophagy/apoptosis and the MyD88-dependent TLR4 signaling pathway.
Zhang F, Dong H, Lv T, Jin K, Jin Y, Zhang X, Jiang J
Journal of neuroinflammation 2018 Sep 20;15(1):273
Journal of neuroinflammation 2018 Sep 20;15(1):273
The toxic effect of aflatoxin B1 on early porcine embryonic development.
Shin KT, Guo J, Niu YJ, Cui XS
Theriogenology 2018 Sep 15;118:157-163
Theriogenology 2018 Sep 15;118:157-163
Autophagy is involved in acetylshikonin ameliorating non-alcoholic steatohepatitis through AMPK/mTOR pathway.
Zeng J, Zhu B, Su M
Biochemical and biophysical research communications 2018 Sep 10;503(3):1645-1650
Biochemical and biophysical research communications 2018 Sep 10;503(3):1645-1650
Activation of AMPK prevents monocrotaline-induced pulmonary arterial hypertension by suppression of NF-κB-mediated autophagy activation.
Zhai C, Shi W, Feng W, Zhu Y, Wang J, Li S, Yan X, Wang Q, Zhang Q, Chai L, Li C, Liu P, Li M
Life sciences 2018 Sep 1;208:87-95
Life sciences 2018 Sep 1;208:87-95
Role of autophagy in regulating the immune response of dendritic cells to Talaromyces marneffei infection.
Chen R, Ji G, Xi L, Zhang T, Zheng D, Li X, Ren H
Microbial pathogenesis 2018 Oct;123:120-125
Microbial pathogenesis 2018 Oct;123:120-125
mTORC1-Regulated and HUWE1-Mediated WIPI2 Degradation Controls Autophagy Flux.
Wan W, You Z, Zhou L, Xu Y, Peng C, Zhou T, Yi C, Shi Y, Liu W
Molecular cell 2018 Oct 18;72(2):303-315.e6
Molecular cell 2018 Oct 18;72(2):303-315.e6
Fluoride induces apoptosis and autophagy through the IL-17 signaling pathway in mice hepatocytes.
Zhao Y, Li Y, Wang J, Manthari RK, Wang J
Archives of toxicology 2018 Nov;92(11):3277-3289
Archives of toxicology 2018 Nov;92(11):3277-3289
Excessive apoptosis and disordered autophagy flux contribute to the neurotoxicity induced by high iodine in Sprague-Dawley rat.
Cui Y, Zhang Z, Zhang B, Zhao L, Hou C, Zeng Q, Nie J, Yu J, Zhao Y, Gao T, Wang A, Liu H
Toxicology letters 2018 Nov;297:24-33
Toxicology letters 2018 Nov;297:24-33
Protective effects of α‑2‑macroglobulin on human bone marrow mesenchymal stem cells in radiation injury.
Liu Y, Cao W, Kong X, Li J, Chen X, Ge Y, Zhong W, Fang S
Molecular medicine reports 2018 Nov;18(5):4219-4228
Molecular medicine reports 2018 Nov;18(5):4219-4228
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
Liu Y, Fan D
Food & function 2018 Nov 14;9(11):5513-5527
Food & function 2018 Nov 14;9(11):5513-5527
Cantharidin suppresses cell growth and migration, and activates autophagy in human non-small cell lung cancer cells.
Liu YP, Li L, Xu L, Dai EN, Chen WD
Oncology letters 2018 May;15(5):6527-6532
Oncology letters 2018 May;15(5):6527-6532
7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway.
Tsai TC, Lai KH, Su JH, Wu YJ, Sheu JH
Marine drugs 2018 Mar 26;16(4)
Marine drugs 2018 Mar 26;16(4)
Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury.
Feng J, Niu P, Chen K, Wu L, Liu T, Xu S, Li J, Li S, Wang W, Lu X, Yu Q, Liu N, Xu L, Wang F, Dai W, Xia Y, Fan X, Guo C
Experimental and therapeutic medicine 2018 Jun;15(6):4599-4614
Experimental and therapeutic medicine 2018 Jun;15(6):4599-4614
Retigabine ameliorates acute stress-induced impairment of spatial memory retrieval through regulating USP2 signaling pathways in hippocampal CA1 area.
Li C, Zhang J, Xu H, Chang M, Lv C, Xue W, Song Z, Zhang L, Zhang X, Tian X
Neuropharmacology 2018 Jun;135:151-162
Neuropharmacology 2018 Jun;135:151-162
Oxidative stress-mediated autophagic cell death participates in the neurotoxic effect on SH-SY5Y cells induced by excessive iodide.
Liu H, Wang L, Zeng Q, Zhao L, Cui Y, Hou C, Zhang B, Zhang Z, Zhang S, Chen X, Wang A
Environmental toxicology 2018 Jun 19;
Environmental toxicology 2018 Jun 19;
The RNA binding protein tristetraprolin down-regulates autophagy in lung adenocarcinoma cells.
Dong F, Li C, Wang P, Deng X, Luo Q, Tang X, Xu L
Experimental cell research 2018 Jun 1;367(1):89-96
Experimental cell research 2018 Jun 1;367(1):89-96
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Lu X, Liu T, Chen K, Xia Y, Dai W, Xu S, Xu L, Wang F, Wu L, Li J, Li S, Wang W, Yu Q, Feng J, Fan X, Zhou Y, Niu P, Guo C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:800-811
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:800-811
Autophagy inhibition attenuates the induction of anti-inflammatory effect of catalpol in liver fibrosis.
Liu Z, Zhu P, Zhang L, Xiong B, Tao J, Guan W, Li C, Chen C, Gu J, Duanmu J, Zhang W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:1262-1271
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:1262-1271
Autophagy defects and related genetic variations in renal cell carcinoma with eosinophilic cytoplasmic inclusions.
Yu Z, Ma J, Li X, Liu Y, Li M, Wang L, Zhao M, He H, Zhang Y, Rao Q, Zhao D, Wang Y, Fan L, Li P, Liu Y, Liu F, Zhang F, Ye J, Yan Q, Guo S, Wang Z
Scientific reports 2018 Jul 2;8(1):9972
Scientific reports 2018 Jul 2;8(1):9972
TLR3 contributes to persistent autophagy and heart failure in mice after myocardial infarction.
Gao T, Zhang SP, Wang JF, Liu L, Wang Y, Cao ZY, Hu QK, Yuan WJ, Lin L
Journal of cellular and molecular medicine 2018 Jan;22(1):395-408
Journal of cellular and molecular medicine 2018 Jan;22(1):395-408
Pseudolaric acid B induced autophagy, but not apoptosis, in MRC5 human fibroblast cells.
Wang Y, Gao H, Wu T, Wang Z, Song F, Chen A, Zhang J, Zhang W, Zhang H, Yu J
Oncology letters 2018 Jan;15(1):863-870
Oncology letters 2018 Jan;15(1):863-870
Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy.
Wei W, An XR, Jin SJ, Li XX, Xu M
Scientific reports 2018 Jan 8;8(1):9
Scientific reports 2018 Jan 8;8(1):9
Excessive ER stress and the resulting autophagic flux dysfunction contribute to fluoride-induced neurotoxicity.
Niu Q, Chen J, Xia T, Li P, Zhou G, Xu C, Zhao Q, Dong L, Zhang S, Wang A
Environmental pollution (Barking, Essex : 1987) 2018 Feb;233:889-899
Environmental pollution (Barking, Essex : 1987) 2018 Feb;233:889-899
The Role of SIRT1 in Autophagy in Lipopolysaccharide-Induced Mouse Type II Alveolar Epithelial Cells.
Liu J, Lv X, Dong W, Hu M, Xu J, Qian G, Li Y
Inflammation 2018 Dec;41(6):2222-2235
Inflammation 2018 Dec;41(6):2222-2235
Lycium barbarum polysaccharide attenuates diabetic testicular dysfunction via inhibition of the PI3K/Akt pathway-mediated abnormal autophagy in male mice.
Shi GJ, Zheng J, Han XX, Jiang YP, Li ZM, Wu J, Chang Q, Niu Y, Sun T, Li YX, Chen Z, Yu JQ
Cell and tissue research 2018 Dec;374(3):653-666
Cell and tissue research 2018 Dec;374(3):653-666
Modulation of autophagy in the protective effect of resveratrol on PM2.5-induced pulmonary oxidative injury in mice.
Li Y, Fu S, Li E, Sun X, Xu H, Meng Y, Wang X, Chen Y, Xie C, Geng S, Wu J, Zhong C, Xu P
Phytotherapy research : PTR 2018 Dec;32(12):2480-2486
Phytotherapy research : PTR 2018 Dec;32(12):2480-2486
Tumor cell-released autophagosomes (TRAPs) promote immunosuppression through induction of M2-like macrophages with increased expression of PD-L1.
Wen ZF, Liu H, Gao R, Zhou M, Ma J, Zhang Y, Zhao J, Chen Y, Zhang T, Huang F, Pan N, Zhang J, Fox BA, Hu HM, Wang LX
Journal for immunotherapy of cancer 2018 Dec 18;6(1):151
Journal for immunotherapy of cancer 2018 Dec 18;6(1):151
Trimetazidine protects against myocardial ischemia/reperfusion injury by inhibiting excessive autophagy.
Wu S, Chang G, Gao L, Jiang D, Wang L, Li G, Luo X, Qin S, Guo X, Zhang D
Journal of molecular medicine (Berlin, Germany) 2018 Aug;96(8):791-806
Journal of molecular medicine (Berlin, Germany) 2018 Aug;96(8):791-806
Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells.
Bai Z, Gao M, Xu X, Zhang H, Xu J, Guan Q, Wang Q, Du J, Li Z, Zuo D, Zhang W, Wu Y
Cell proliferation 2018 Aug;51(4):e12450
Cell proliferation 2018 Aug;51(4):e12450
Subthalamic nucleus deep brain stimulation protects neurons by activating autophagy via PP2A inactivation in a rat model of Parkinson's disease.
Du TT, Chen YC, Lu YQ, Meng FG, Yang H, Zhang JG
Experimental neurology 2018 Aug;306:232-242
Experimental neurology 2018 Aug;306:232-242
Hispidulin alleviates high-glucose-induced podocyte injury by regulating protective autophagy.
Wu F, Li S, Zhang N, Huang W, Li X, Wang M, Bai D, Han B
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:307-314
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:307-314
The gastric mucosal protective effects of astragaloside IV in mnng-induced GPL rats.
Cai T, Zhang C, Zhao Z, Li S, Cai H, Chen X, Cai D, Liu W, Yan Y, Xie K, Pan H, Zeng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:291-299
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:291-299
Autophagy is required for proper meiosis of porcine oocytes maturing in vitro.
Shen XH, Jin YX, Liang S, Kwon JW, Zhu JW, Lei L, Kim NH
Scientific reports 2018 Aug 22;8(1):12581
Scientific reports 2018 Aug 22;8(1):12581
Lycium barbarum polysaccharide protects diabetic peripheral neuropathy by enhancing autophagy via mTOR/p70S6K inhibition in Streptozotocin-induced diabetic rats.
Liu SY, Chen L, Li XC, Hu QK, He LJ
Journal of chemical neuroanatomy 2018 Apr;89:37-42
Journal of chemical neuroanatomy 2018 Apr;89:37-42
Traditional Chinese Medicine CFF-1 induced cell growth inhibition, autophagy, and apoptosis via inhibiting EGFR-related pathways in prostate cancer.
Wu Z, Zhu Q, Yin Y, Kang D, Cao R, Tian Q, Zhang Y, Lu S, Liu P
Cancer medicine 2018 Apr;7(4):1546-1559
Cancer medicine 2018 Apr;7(4):1546-1559
Increased autophagy in EOC re-ascites cells can inhibit cell death and promote drug resistance.
Liu Y, Tang J, Liu D, Zhang L, He Y, Li J, Gao L, Tang D, Jin X, Kong D
Cell death & disease 2018 Apr 1;9(4):419
Cell death & disease 2018 Apr 1;9(4):419
Assessment of Posttranslational Modifications of ATG proteins.
Xie Y, Kang R, Tang D
Methods in enzymology 2017;587:171-188
Methods in enzymology 2017;587:171-188
Hydrogen Gas Attenuates Myocardial Ischemia Reperfusion Injury Independent of Postconditioning in Rats by Attenuating Endoplasmic Reticulum Stress-Induced Autophagy.
Gao Y, Yang H, Chi J, Xu Q, Zhao L, Yang W, Liu W, Yang W
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(4):1503-1514
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(4):1503-1514
Ox-LDL-Induced MicroRNA-155 Promotes Autophagy in Human Endothelial Cells via Repressing the Rheb/ mTOR Pathway.
Lv J, Yang L, Guo R, Shi Y, Zhang Z, Ye J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(4):1436-1448
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(4):1436-1448
Quercetin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy by Inhibiting ERK/NF-κB Pathway.
Wu L, Zhang Q, Dai W, Li S, Feng J, Li J, Liu T, Xu S, Wang W, Lu X, Yu Q, Chen K, Xia Y, Lu J, Zhou Y, Fan X, Guo C
Gastroenterology research and practice 2017;2017:9724217
Gastroenterology research and practice 2017;2017:9724217
HSPB8 Promotes the Fusion of Autophagosome and Lysosome during Autophagy in Diabetic Neurons.
Li XC, Hu QK, Chen L, Liu SY, Su S, Tao H, Zhang LN, Sun T, He LJ
International journal of medical sciences 2017;14(13):1335-1341
International journal of medical sciences 2017;14(13):1335-1341
Salidroside pretreatment attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting the mitogen-activated protein kinase pathway in mice.
Feng J, Zhang Q, Mo W, Wu L, Li S, Li J, Liu T, Xu S, Fan X, Guo C
Drug design, development and therapy 2017;11:1989-2006
Drug design, development and therapy 2017;11:1989-2006
Combination of Endothelial-Monocyte-Activating Polypeptide-II with Temozolomide Suppress Malignant Biological Behaviors of Human Glioblastoma Stem Cells via miR-590-3p/MACC1 Inhibiting PI3K/AKT/mTOR Signal Pathway.
Zhou W, Liu L, Xue Y, Zheng J, Liu X, Ma J, Li Z, Liu Y
Frontiers in molecular neuroscience 2017;10:68
Frontiers in molecular neuroscience 2017;10:68
Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis.
Zhao Z, Zhang L, Guo XD, Cao LL, Xue TF, Zhao XJ, Yang DD, Yang J, Ji J, Huang JY, Sun XL
Frontiers in molecular neuroscience 2017;10:293
Frontiers in molecular neuroscience 2017;10:293
Hyperlipidemia impairs erectile function in rats by causing cavernosal fibrosis.
Li R, Cui K, Wang T, Wang S, Li X, Qiu J, Yu G, Liu J, Wen B, Rao K
Andrologia 2017 Sep;49(7)
Andrologia 2017 Sep;49(7)
Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.
Liu M, Liang K, Zhen J, Zhou M, Wang X, Wang Z, Wei X, Zhang Y, Sun Y, Zhou Z, Su H, Zhang C, Li N, Gao C, Peng J, Yi F
Nature communications 2017 Sep 4;8(1):413
Nature communications 2017 Sep 4;8(1):413
VPS34 Acetylation Controls Its Lipid Kinase Activity and the Initiation of Canonical and Non-canonical Autophagy.
Su H, Yang F, Wang Q, Shen Q, Huang J, Peng C, Zhang Y, Wan W, Wong CCL, Sun Q, Wang F, Zhou T, Liu W
Molecular cell 2017 Sep 21;67(6):907-921.e7
Molecular cell 2017 Sep 21;67(6):907-921.e7
Pretreatment with propylene glycol alginate sodium sulfate ameliorated concanavalin A-induced liver injury by regulating the PI3K/Akt pathway in mice.
Xu S, Wu L, Zhang Q, Feng J, Li S, Li J, Liu T, Mo W, Wang W, Lu X, Yu Q, Chen K, Xia Y, Lu J, Xu L, Zhou Y, Fan X, Guo C
Life sciences 2017 Sep 15;185:103-113
Life sciences 2017 Sep 15;185:103-113
The natural product fucoidan ameliorates hepatic ischemia-reperfusion injury in mice.
Li J, Zhang Q, Li S, Dai W, Feng J, Wu L, Liu T, Chen K, Xia Y, Lu J, Zhou Y, Fan X, Guo C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:687-696
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:687-696
Role of autophagy in cadmium-induced testicular injury.
Wang YJ, Yan J, Yin F, Li L, Qin YG, Meng CY, Lu RF, Guo L
Human & experimental toxicology 2017 Oct;36(10):1039-1048
Human & experimental toxicology 2017 Oct;36(10):1039-1048
Circular RNA HIPK2 regulates astrocyte activation via cooperation of autophagy and ER stress by targeting MIR124-2HG.
Huang R, Zhang Y, Han B, Bai Y, Zhou R, Gan G, Chao J, Hu G, Yao H
Autophagy 2017 Oct 3;13(10):1722-1741
Autophagy 2017 Oct 3;13(10):1722-1741
The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma.
Chen S, Wu DD, Sang XB, Wang LL, Zong ZH, Sun KX, Liu BL, Zhao Y
Cell death & disease 2017 Oct 12;8(10):e3118
Cell death & disease 2017 Oct 12;8(10):e3118
Fluoride-Induced Autophagy via the Regulation of Phosphorylation of Mammalian Targets of Rapamycin in Mice Leydig Cells.
Zhang J, Zhu Y, Shi Y, Han Y, Liang C, Feng Z, Zheng H, Eng M, Wang J
Journal of agricultural and food chemistry 2017 Oct 11;65(40):8966-8976
Journal of agricultural and food chemistry 2017 Oct 11;65(40):8966-8976
PD149163 induces hypothermia to protect against brain injury in acute cerebral ischemic rats.
Xue TF, Ding X, Ji J, Yan H, Huang JY, Guo XD, Yang J, Sun XL
Journal of pharmacological sciences 2017 Nov;135(3):105-113
Journal of pharmacological sciences 2017 Nov;135(3):105-113
The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity.
Xu S, Niu P, Chen K, Xia Y, Yu Q, Liu N, Li J, Li S, Wu L, Feng J, Wang W, Lu X, Liu T, Wang F, Dai W, Fan X, Mo W, Xu L, Guo C
Scientific reports 2017 Nov 9;7(1):15175
Scientific reports 2017 Nov 9;7(1):15175
Anti-osteoclastogenesis of Mineral Trioxide Aggregate through Inhibition of the Autophagic Pathway.
Cheng X, Zhu L, Zhang J, Yu J, Liu S, Lv F, Lin Y, Liu G, Peng B
Journal of endodontics 2017 May;43(5):766-773
Journal of endodontics 2017 May;43(5):766-773
15-Deoxy-Δ12,14-prostaglandin J2 alleviates hepatic ischemia-reperfusion injury in mice via inducing antioxidant response and inhibiting apoptosis and autophagy.
Chen K, Li JJ, Li SN, Feng J, Liu T, Wang F, Dai WQ, Xia YJ, Lu J, Zhou YQ, Guo CY
Acta pharmacologica Sinica 2017 May;38(5):672-687
Acta pharmacologica Sinica 2017 May;38(5):672-687
FGF2/FGFR1 regulates autophagy in FGFR1-amplified non-small cell lung cancer cells.
Yuan H, Li ZM, Shao J, Ji WX, Xia W, Lu S
Journal of experimental & clinical cancer research : CR 2017 May 30;36(1):72
Journal of experimental & clinical cancer research : CR 2017 May 30;36(1):72
Defective autophagy is associated with neuronal injury in a mouse model of multiple sclerosis.
Feng X, Hou H, Zou Y, Guo L
Bosnian journal of basic medical sciences 2017 May 20;17(2):95-103
Bosnian journal of basic medical sciences 2017 May 20;17(2):95-103
Cucurbitacin B induces autophagy and apoptosis by suppressing CIP2A/PP2A/mTORC1 signaling axis in human cisplatin resistant gastric cancer cells.
Liu X, Duan C, Ji J, Zhang T, Yuan X, Zhang Y, Ma W, Yang J, Yang L, Jiang Z, Yu H, Liu Y
Oncology reports 2017 Jul;38(1):271-278
Oncology reports 2017 Jul;38(1):271-278
7-O-geranylquercetin-induced autophagy contributes to apoptosis via ROS generation in human non-small cell lung cancer cells.
Wang EX, Zou BY, Shi L, Du LY, Zhu YY, Jiang YM, Ma XD, Kang XH, Wang CY, Zhen YH, Sun LD
Life sciences 2017 Jul 1;180:102-113
Life sciences 2017 Jul 1;180:102-113
Propylene Glycol Alginate Sodium Sulfate Alleviates Cerulein-Induced Acute Pancreatitis by Modulating the MEK/ERK Pathway in Mice.
Zhang H, Li Y, Li L, Liu H, Hu L, Dai Y, Chen J, Xu S, Chen W, Xu X, Xu X
Marine drugs 2017 Feb 17;15(2)
Marine drugs 2017 Feb 17;15(2)
Hydrogen Sulphide modulating mitochondrial morphology to promote mitophagy in endothelial cells under high-glucose and high-palmitate.
Liu N, Wu J, Zhang L, Gao Z, Sun Y, Yu M, Zhao Y, Dong S, Lu F, Zhang W
Journal of cellular and molecular medicine 2017 Dec;21(12):3190-3203
Journal of cellular and molecular medicine 2017 Dec;21(12):3190-3203
Effects of dimethyl carbonate-induced autophagic activation on follicular development in the mouse ovary.
Tang Z, Zhang Z, Tang Y, Qi L, Yang F, Wang Z
Experimental and therapeutic medicine 2017 Dec;14(6):5981-5989
Experimental and therapeutic medicine 2017 Dec;14(6):5981-5989
3-Methyladenine ameliorates liver fibrosis through autophagy regulated by the NF-κB signaling pathways on hepatic stellate cell.
Wang B, Yang H, Fan Y, Yang Y, Cao W, Jia Y, Cao Y, Sun K, Pang Z, Du H
Oncotarget 2017 Dec 8;8(64):107603-107611
Oncotarget 2017 Dec 8;8(64):107603-107611
Calpain Inhibition Is Protective in Machado-Joseph Disease Zebrafish Due to Induction of Autophagy.
Watchon M, Yuan KC, Mackovski N, Svahn AJ, Cole NJ, Goldsbury C, Rinkwitz S, Becker TS, Nicholson GA, Laird AS
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Aug 9;37(32):7782-7794
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Aug 9;37(32):7782-7794
Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways.
Wu L, Zhang Q, Mo W, Feng J, Li S, Li J, Liu T, Xu S, Wang W, Lu X, Yu Q, Chen K, Xia Y, Lu J, Xu L, Zhou Y, Fan X, Guo C
Scientific reports 2017 Aug 24;7(1):9289
Scientific reports 2017 Aug 24;7(1):9289
Exogenous H2S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy.
Wu J, Tian Z, Sun Y, Lu C, Liu N, Gao Z, Zhang L, Dong S, Yang F, Zhong X, Xu C, Lu F, Zhang W
Cell death & disease 2017 Aug 10;8(8):e2992
Cell death & disease 2017 Aug 10;8(8):e2992
Pre-incubation with hucMSC-exosomes prevents cisplatin-induced nephrotoxicity by activating autophagy.
Wang B, Jia H, Zhang B, Wang J, Ji C, Zhu X, Yan Y, Yin L, Yu J, Qian H, Xu W
Stem cell research & therapy 2017 Apr 8;8(1):75
Stem cell research & therapy 2017 Apr 8;8(1):75
Sensitization of tamoxifen-resistant breast cancer cells by Z-ligustilide through inhibiting autophagy and accumulating DNA damages.
Qi H, Jiang Z, Wang C, Yang Y, Li L, He H, Yu Z
Oncotarget 2017 Apr 25;8(17):29300-29317
Oncotarget 2017 Apr 25;8(17):29300-29317
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
Liu J, Wu J, Sun A, Sun Y, Yu X, Liu N, Dong S, Yang F, Zhang L, Zhong X, Xu C, Lu F, Zhang W
Cell & bioscience 2016;6:33
Cell & bioscience 2016;6:33
Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway-mediated inhibition of extracellular matrix and autophagy.
Li J, Chen K, Li S, Feng J, Liu T, Wang F, Zhang R, Xu S, Zhou Y, Zhou S, Xia Y, Lu J, Zhou Y, Guo C
Drug design, development and therapy 2016;10:619-30
Drug design, development and therapy 2016;10:619-30
Novel recombinant protein FlaA N/C increases tumor radiosensitivity via NF-κB signaling in murine breast cancer cells.
Xu Y, Wu D, Fan Y, Li P, Du H, Shi J, Wang D, Zhou X
Oncology letters 2016 Oct;12(4):2632-2640
Oncology letters 2016 Oct;12(4):2632-2640
Aliskiren targets multiple systems to alleviate cancer cachexia.
Wang C, Guo D, Wang Q, You S, Qiao Z, Liu Y, Dai H, Tang H
Oncology reports 2016 Nov;36(5):3014-3022
Oncology reports 2016 Nov;36(5):3014-3022
Cytoprotective effect of autophagy on phagocytosis of apoptotic cells by macrophages.
Zhou P, Tan YZ, Wang HJ, Li T, He T, Yu Y, Zhang J, Zhang D
Experimental cell research 2016 Nov 1;348(2):165-176
Experimental cell research 2016 Nov 1;348(2):165-176
Inhibition of AMP-activated protein kinase alleviates focal cerebral ischemia injury in mice: Interference with mTOR and autophagy.
Fu L, Huang L, Cao C, Yin Q, Liu J
Brain research 2016 Nov 1;1650:103-111
Brain research 2016 Nov 1;1650:103-111
15d-PGJ2 alleviates ConA-induced acute liver injury in mice by up-regulating HO-1 and reducing hepatic cell autophagy.
Chen K, Li J, Li S, Feng J, Wu L, Liu T, Zhang R, Xu S, Cheng K, Zhou Y, Zhou S, Wang F, Dai W, Xia Y, Lu J, Zhou Y, Guo C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 May;80:183-192
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 May;80:183-192
Excessive apoptosis and defective autophagy contribute to developmental testicular toxicity induced by fluoride.
Zhang S, Niu Q, Gao H, Ma R, Lei R, Zhang C, Xia T, Li P, Xu C, Wang C, Chen J, Dong L, Zhao Q, Wang A
Environmental pollution (Barking, Essex : 1987) 2016 May;212:97-104
Environmental pollution (Barking, Essex : 1987) 2016 May;212:97-104
Pseudolaric acid B activates autophagy in MCF-7 human breast cancer cells to prevent cell death.
Yu J, Chen C, Xu T, Yan M, Xue B, Wang Y, Liu C, Zhong T, Wang Z, Meng X, Hu D, Yu X
Oncology letters 2016 Mar;11(3):1731-1737
Oncology letters 2016 Mar;11(3):1731-1737
Synergistic chemopreventive effects of curcumin and berberine on human breast cancer cells through induction of apoptosis and autophagic cell death.
Wang K, Zhang C, Bao J, Jia X, Liang Y, Wang X, Chen M, Su H, Li P, Wan JB, He C
Scientific reports 2016 Jun 6;6:26064
Scientific reports 2016 Jun 6;6:26064
Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways.
Huang Q, Zhan L, Cao H, Li J, Lyu Y, Guo X, Zhang J, Ji L, Ren T, An J, Liu B, Nie Y, Xing J
Autophagy 2016 Jun 2;12(6):999-1014
Autophagy 2016 Jun 2;12(6):999-1014
Preventive Effects of a Novel Polysaccharide from Sepia esculenta Ink on Ovarian Failure and Its Action Mechanisms in Cyclophosphamide-Treated Mice.
Liu HZ, Tao YX, Luo P, Deng CM, Gu YP, Yang L, Zhong JP
Journal of agricultural and food chemistry 2016 Jul 20;64(28):5759-66
Journal of agricultural and food chemistry 2016 Jul 20;64(28):5759-66
Effects of Atrazine and Chlorpyrifos on Autophagy-Related Genes in the Brain of Common Carp: Health-Risk Assessments.
Xing HJ, Wang LL, Yao HD, Wang XL, Xu SW
Archives of environmental contamination and toxicology 2016 Feb;70(2):301-10
Archives of environmental contamination and toxicology 2016 Feb;70(2):301-10
Effects of Placental Ischemia Are Attenuated by 1,25-Dihydroxyvitamin D Treatment and Associated with Reduced Apoptosis and Increased Autophagy.
Tian X, Ma S, Wang Y, Hou L, Shi Y, Yao M, Wang X, Zhang H, Jiang L
DNA and cell biology 2016 Feb;35(2):59-70
DNA and cell biology 2016 Feb;35(2):59-70
Overexpression of RBM5 induces autophagy in human lung adenocarcinoma cells.
Su Z, Wang K, Li R, Yin J, Hao Y, Lv X, Li J, Zhao L, Du Y, Li P, Zhang J
World journal of surgical oncology 2016 Feb 29;14:57
World journal of surgical oncology 2016 Feb 29;14:57
Fentanyl induces autophagy via activation of the ROS/MAPK pathway and reduces the sensitivity of cisplatin in lung cancer cells.
Yao J, Ma C, Gao W, Liang J, Liu C, Yang H, Yan Q, Wen Q
Oncology reports 2016 Dec;36(6):3363-3370
Oncology reports 2016 Dec;36(6):3363-3370
Decreased Level of Klotho Contributes to Drug Resistance in Lung Cancer Cells: Involving in Klotho-Mediated Cell Autophagy.
Chen T, Ren H, Thakur A, Yang T, Li Y, Zhang S, Wang T, Chen M
DNA and cell biology 2016 Dec;35(12):751-757
DNA and cell biology 2016 Dec;35(12):751-757
Dimethyl α-ketoglutarate reduces CCl4-induced liver fibrosis through inhibition of autophagy in hepatic stellate cells.
Zhao J, Peng L, Cui R, Guo X, Yan M
Biochemical and biophysical research communications 2016 Dec 2;481(1-2):90-96
Biochemical and biophysical research communications 2016 Dec 2;481(1-2):90-96
Anti-osteoclastogenic activity of isoliquiritigenin via inhibition of NF-κB-dependent autophagic pathway.
Liu S, Zhu L, Zhang J, Yu J, Cheng X, Peng B
Biochemical pharmacology 2016 Apr 15;106:82-93
Biochemical pharmacology 2016 Apr 15;106:82-93
Low doses of single or combined agrichemicals induces α-synuclein aggregation in nigrostriatal system of mice through inhibition of proteasomal and autophagic pathways.
Su C, Niu P
International journal of clinical and experimental medicine 2015;8(11):20508-15
International journal of clinical and experimental medicine 2015;8(11):20508-15
Inhibition of Notch Signaling Promotes the Adipogenic Differentiation of Mesenchymal Stem Cells Through Autophagy Activation and PTEN-PI3K/AKT/mTOR Pathway.
Song BQ, Chi Y, Li X, Du WJ, Han ZB, Tian JJ, Li JJ, Chen F, Wu HH, Han LX, Lu SH, Zheng YZ, Han ZC
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;36(5):1991-2002
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;36(5):1991-2002
GBA deficiency promotes SNCA/α-synuclein accumulation through autophagic inhibition by inactivated PPP2A.
Du TT, Wang L, Duan CL, Lu LL, Zhang JL, Gao G, Qiu XB, Wang XM, Yang H
Autophagy 2015;11(10):1803-20
Autophagy 2015;11(10):1803-20
Inhibition of autophagy by 3-MA enhances IL-24-induced apoptosis in human oral squamous cell carcinoma cells.
Li J, Yang D, Wang W, Piao S, Zhou J, Saiyin W, Zheng C, Sun H, Li Y
Journal of experimental & clinical cancer research : CR 2015 Sep 11;34:97
Journal of experimental & clinical cancer research : CR 2015 Sep 11;34:97
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
Mao Y, Zhang S, Yu F, Li H, Guo C, Fan X
International journal of molecular sciences 2015 Sep 10;16(9):21911-30
International journal of molecular sciences 2015 Sep 10;16(9):21911-30
Pseudolaric acid B inhibits proliferation in SW579 human thyroid squamous cell carcinoma.
Yu J, Ren P, Zhong T, Wang Y, Yan M, Xue B, Li R, Dai C, Liu C, Chen G, Yu XF
Molecular medicine reports 2015 Nov;12(5):7195-202
Molecular medicine reports 2015 Nov;12(5):7195-202
Astaxanthin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy via the ROS/MAPK Pathway in Mice.
Li J, Wang F, Xia Y, Dai W, Chen K, Li S, Liu T, Zheng Y, Wang J, Lu W, Zhou Y, Yin Q, Lu J, Zhou Y, Guo C
Marine drugs 2015 May 27;13(6):3368-87
Marine drugs 2015 May 27;13(6):3368-87
Autophagy in SDF-1α-mediated DPSC migration and pulp regeneration.
Yang JW, Zhang YF, Wan CY, Sun ZY, Nie S, Jian SJ, Zhang L, Song GT, Chen Z
Biomaterials 2015 Mar;44:11-23
Biomaterials 2015 Mar;44:11-23
Suppression of murine experimental autoimmune encephalomyelitis development by 1,25-dihydroxyvitamin D3 with autophagy modulation.
Zhen C, Feng X, Li Z, Wang Y, Li B, Li L, Quan M, Wang G, Guo L
Journal of neuroimmunology 2015 Mar 15;280:1-7
Journal of neuroimmunology 2015 Mar 15;280:1-7
Ischemic postconditioning regulates cardiomyocyte autophagic activity following ischemia/reperfusion injury.
Guo L, Xu JM, Mo XY
Molecular medicine reports 2015 Jul;12(1):1169-76
Molecular medicine reports 2015 Jul;12(1):1169-76
Potent effects of dioscin against obesity in mice.
Liu M, Xu L, Yin L, Qi Y, Xu Y, Han X, Zhao Y, Sun H, Yao J, Lin Y, Liu K, Peng J
Scientific reports 2015 Jan 22;5:7973
Scientific reports 2015 Jan 22;5:7973
Suppression of autophagy augments the radiosensitizing effects of STAT3 inhibition on human glioma cells.
Yuan X, Du J, Hua S, Zhang H, Gu C, Wang J, Yang L, Huang J, Yu J, Liu F
Experimental cell research 2015 Jan 15;330(2):267-276
Experimental cell research 2015 Jan 15;330(2):267-276
Tonsil-derived mesenchymal stem cells ameliorate CCl4-induced liver fibrosis in mice via autophagy activation.
Park M, Kim YH, Woo SY, Lee HJ, Yu Y, Kim HS, Park YS, Jo I, Park JW, Jung SC, Lee H, Jeong B, Ryu KH
Scientific reports 2015 Feb 27;5:8616
Scientific reports 2015 Feb 27;5:8616
SZC017, a novel oleanolic acid derivative, induces apoptosis and autophagy in human breast cancer cells.
Gao L, Wang Y, Xu Z, Li X, Wu J, Liu S, Chu P, Sun Z, Sun B, Lin Y, Peng J, Han G, Wang S, Tang Z
Apoptosis : an international journal on programmed cell death 2015 Dec;20(12):1636-50
Apoptosis : an international journal on programmed cell death 2015 Dec;20(12):1636-50
Chemoresistance is associated with Beclin-1 and PTEN expression in epithelial ovarian cancers.
Ying H, Qu D, Liu C, Ying T, Lv J, Jin S, Xu H
Oncology letters 2015 Apr;9(4):1759-1763
Oncology letters 2015 Apr;9(4):1759-1763
Autophagy is involved in the cardioprotection effect of remote limb ischemic postconditioning on myocardial ischemia/reperfusion injury in normal mice, but not diabetic mice.
Han Z, Cao J, Song D, Tian L, Chen K, Wang Y, Gao L, Yin Z, Fan Y, Wang C
PloS one 2014;9(1):e86838
PloS one 2014;9(1):e86838
Over-expression of Beclin-1 facilitates acquired resistance to histone deacetylase inhibitor-induced apoptosis.
Wang SM, Li XH, Xiu ZL
Asian Pacific journal of cancer prevention : APJCP 2014;15(18):7913-7
Asian Pacific journal of cancer prevention : APJCP 2014;15(18):7913-7
Bone marrow mesenchymal stem cells repair spinal cord ischemia/reperfusion injury by promoting axonal growth and anti-autophagy.
Yin F, Meng C, Lu R, Li L, Zhang Y, Chen H, Qin Y, Guo L
Neural regeneration research 2014 Sep 15;9(18):1665-71
Neural regeneration research 2014 Sep 15;9(18):1665-71
Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis.
Dong D, Xu L, Han X, Qi Y, Xu Y, Yin L, Liu K, Peng J
Molecules (Basel, Switzerland) 2014 May 30;19(6):7189-206
Molecules (Basel, Switzerland) 2014 May 30;19(6):7189-206
Molecular characterization and expression analysis of the autophagic gene beclin 1 from the purse red common carp (Cyprinus carpio) exposed to cadmium.
Gao D, Xu Z, Kuang X, Qiao P, Liu S, Zhang L, He P, Jadwiga WS, Wang Y, Min W
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2014 Mar;160:15-22
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2014 Mar;160:15-22
Ubiquitin‑specific protease 22‑induced autophagy is correlated with poor prognosis of pancreatic cancer.
Liang JX, Ning Z, Gao W, Ling J, Wang AM, Luo HF, Liang Y, Yan Q, Wang ZY
Oncology reports 2014 Dec;32(6):2726-34
Oncology reports 2014 Dec;32(6):2726-34
Dissection of autophagy in human platelets.
Feng W, Chang C, Luo D, Su H, Yu S, Hua W, Chen Z, Hu H, Liu W
Autophagy 2014 Apr;10(4):642-51
Autophagy 2014 Apr;10(4):642-51
Role of membrane association and Atg14-dependent phosphorylation in beclin-1-mediated autophagy.
Fogel AI, Dlouhy BJ, Wang C, Ryu SW, Neutzner A, Hasson SA, Sideris DP, Abeliovich H, Youle RJ
Molecular and cellular biology 2013 Sep;33(18):3675-88
Molecular and cellular biology 2013 Sep;33(18):3675-88
Cathepsin L stimulates autophagy and inhibits apoptosis of ox-LDL-induced endothelial cells: potential role in atherosclerosis.
Wei DH, Jia XY, Liu YH, Guo FX, Tang ZH, Li XH, Wang Z, Liu LS, Wang GX, Jian ZS, Ruan CG
International journal of molecular medicine 2013 Feb;31(2):400-6
International journal of molecular medicine 2013 Feb;31(2):400-6
Autophagy in endothelial progenitor cells is cytoprotective in hypoxic conditions.
Wang HJ, Zhang D, Tan YZ, Li T
American journal of physiology. Cell physiology 2013 Apr 1;304(7):C617-26
American journal of physiology. Cell physiology 2013 Apr 1;304(7):C617-26
Depletion of Bmi-1 enhances 5-fluorouracil-induced apoptosis and autophagy in hepatocellular carcinoma cells.
Wu J, Hu D, Zhang R
Oncology letters 2012 Oct;4(4):723-726
Oncology letters 2012 Oct;4(4):723-726
DJ-1 protects dopaminergic neurons against rotenone-induced apoptosis by enhancing ERK-dependent mitophagy.
Gao H, Yang W, Qi Z, Lu L, Duan C, Zhao C, Yang H
Journal of molecular biology 2012 Oct 19;423(2):232-48
Journal of molecular biology 2012 Oct 19;423(2):232-48
Role of autophagy in monokine induced by interferon γ (Mig) production during adenovirus-hepatitis B virus infection.
Xia Y, Zeng D, Yu F, He J, Zhou Z, Tu W, Deng H, Tian DA, Liu M
Hepato-gastroenterology 2012 Jun;59(116):1245-50
Hepato-gastroenterology 2012 Jun;59(116):1245-50
Loss of PINK1 function decreases PP2A activity and promotes autophagy in dopaminergic cells and a murine model.
Qi Z, Yang W, Liu Y, Cui T, Gao H, Duan C, Lu L, Zhao C, Zhao H, Yang H
Neurochemistry international 2011 Oct;59(5):572-81
Neurochemistry international 2011 Oct;59(5):572-81
Silencing of PINK1 induces mitophagy via mitochondrial permeability transition in dopaminergic MN9D cells.
Cui T, Fan C, Gu L, Gao H, Liu Q, Zhang T, Qi Z, Zhao C, Zhao H, Cai Q, Yang H
Brain research 2011 Jun 7;1394:1-13
Brain research 2011 Jun 7;1394:1-13
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MDA-MB-453s cells were subjected to SDS PAGE followed by western blot with 11306-1-AP( Beclin 1 Antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-Beclin 1 (IP:11306-1-AP, 3ug; Detection:11306-1-AP 1:500) with HeLa cells lysate 1200ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Beclin 1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Beclin 1. This antibody recognizes human, mouse, rat antigen. The Beclin 1 antibody has been validated for the following applications: ELISA, IHC, IP, WB analysis.