FNab06615

antibody from FineTest Biotech

Targeting: POLR1A DKFZP586M0122, FLJ21915, RPA1, RPA190, RPO1-4

Western blot

ELISA

Antibody data

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Validation data

Product number: FNab06615 - Provider product page
Provider: FineTest Biotech
Product name: POLR1A antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I. A bridging helix emanates from RPA1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol I by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition(By similarity).
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: polymerase(RNA) I polypeptide A, 19 4kDa
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

POLR1A protein structure - FNab06615 shown in red.