BS6060

antibody from Bioworld Technology, Inc

Targeting: TTK CT96, MPH1, MPS1, MPS1L1

Immunohistochemistry

Antibody data

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Validation data

Product number: BS6060 - Provider product page
Provider: Bioworld Technology, Inc
Product name: TTK polyclonal antibody
Antibody type: Polyclonal
Antigen: Recombinant full length Human TTK.
Description: This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

TTK protein structure - BS6060 shown in red.