AMM04262G

antibody from Leading Biology

Targeting: TTK CT96, MPH1, MPS1, MPS1L1

Western blot (Recommended by provider)

Antibody Data

Product number

AMM04262G

Provider

Leading Biology

Product name

TTK Antibody (monoclonal) (M02)

Antibody type

Monoclonal

Description

This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

4G9

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.