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- Antibody Data
- Antigen structure
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- Flow cytometry [1]
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- Product number
- 306102 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#306102, RRID:AB_2229992
- Product name
- Purified anti-human CD131
- Antibody type
- Monoclonal
- Antigen
- Human IL-3R β chain transfected COS cells
- Description
- CD131, also known as the IL-3R common β subunit (βC), is a 95-120 kD type I transmembrane glycoprotein and belongs to the Ig superfamily. The common β subunit associates with the specific α subunits of IL-3 receptor, IL-5 receptor and GM-CSF receptor to form high affinity receptors for these cytokines. These cytokine receptors are expressed by neutrophils, eosinophils, monocytes, endothelial cells, fibroblasts and hematopoietic progenitor cells and play a crucial role in growth/activation of eosinophils and in the inflammatory response. The 1C1 antibody is a non-blocking antibody.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4° C.
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- BioLegend (provider)
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- Experimental details
- CD131 transfected cell stained with purified 1C1, followed by anti-mouse IgG FITC
- Conjugate
- Unconjugated
