Ab170834

antibody from Aladdin Scientific Corporation

Targeting: IGF1R CD221, IGFIR, IGFR, JTK13, MGC18216

ELISA (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Functional assay (Data presented on provider website)

Antibody Data

Product number

Ab170834

Provider

Aladdin Scientific Corporation

Product name

Teprotumumab (anti-IGF1R)

Antibody type

Recombinant

Description

Teprotumumab (anti-IGF1R) is an IGF-1 receptor (IGF-1R) blocking human monoclonal antibody. Teprotumumab (anti-IGF1R) binds to the ligand binding extracellular α-subunit domain of IGF-1R. Teprotumumab (anti-IGF1R) inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab (anti-IGF1R) attenuates TSH-dependent IL-6 and IL-8 expression and Akt phosphorylation. Teprotumumab (anti-IGF1R) can be used for thyroid-associated ophthalmopathy research.Purity>95% (SDS-PAGE&SEC)Endotoxin Level< 1.0EU/mg

Reactivity

Human

Conjugate

Unconjugated

Vial size

10mg,1mg,5mg

Concentration

Lot by Lot

Storage

Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.