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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- Ab170834 - Provider product page
- Provider
- Aladdin Scientific
- Product name
- Teprotumumab (anti-IGF1R)
- Antibody type
- Recombinant
- Description
- Teprotumumab (anti-IGF1R) is an IGF-1 receptor (IGF-1R) blocking human monoclonal antibody. Teprotumumab (anti-IGF1R) binds to the ligand binding extracellular _-subunit domain of IGF-1R. Teprotumumab (anti-IGF1R) inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab (anti-IGF1R) attenuates TSH-dependent IL-6 and IL-8 expression and Akt phosphorylation. Teprotumumab (anti-IGF1R) can be used for thyroid-associated ophthalmopathy research.Purity>95% (SDS-PAGE&SEC)Endotoxin Level< 1.0EU/mg
- Reactivity
- Human
- Conjugate
- Unconjugated
- Vial size
- 100_g,10mg,1mg,5mg
- Concentration
- Lot by Lot
- Storage
- Store at -80_ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
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Supportive validation
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- Aladdin Scientific (provider)
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- Experimental details
- Teprotumumab (anti-IGF1R) (Ab170834) - Flow Cytometry Flow Cytometry analysis of MCF-7 cells labelling IGF1R (red) with Teprotumumab (anti-IGF1R) (Ab170834). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
