BS9175

antibody from Bioworld Technology, Inc
Targeting: PIK3CG
Provider product page for BS9175
Western blot
Immunohistochemistry

Antibody data

Product number
BS9175 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PI3K p110ÎÛ (L89) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 50-100 of Human PI3K p110ÎÛ.
Description
Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85Ï« and p85ÉÇ), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110Ï« and p110ÉÇ interact with p85Ï«, and p110Ï« has also been shown to interact with p85ÉÇ in vitro. p110ÎÛ expression is restricted to white blood cells. It has been shown to bind p85Ï« and ÉÇ, but it apparently does not phosphorylate these subunits. p110ÎÛ seems to have the capacity to autophosphorylate. p110 does not interact with the p85 subunits. It has been shown to be activated by Ï« and ÉÇ heterotrimeric G proteins.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PIK3CG protein structure - BS9175 shown in red.