BS8357

antibody from Bioworld Technology, Inc
Targeting: PIK3CG
Provider product page for BS8357
Western blot
Immunohistochemistry

Antibody data

Product number
BS8357 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PIK3CG polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PIK3CG.
Description
Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits.p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85Ï« and p85ÉÇ), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110Ï« and p110ÉÇ interact with p85Ï«, and p110Ï« has also been shown to interact with p85ÉÇ in vitro. p110Ñ´ expression is restricted to white blood cells. It has been shown to bind p85Ï« and p85ÉÇ, but it apparently does not phosphorylate these subunits. p110Ñ´ seems to have the capacity to autophosphorylate. p110ÎÛ does not interact with the p85 subunits. It has been shown to be activated by Ï« and ÉÇÎÛ heterotrimeric G proteins.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PIK3CG protein structure - BS8357 shown in red.