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- Antibody Data
- Antigen structure
- References [1]
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- ELISA [1]
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- Product number
- 502502 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#502502, RRID:AB_315227
- Product name
- Purified anti-human IFN-
- Antibody type
- Monoclonal
- Antigen
- Partially purified, native human IFN-γ
- Description
- Interferon-γ is a potent multifunctional cytokine which is secreted primarily by activated NK cells and T cells. Originally characterized based on anti-viral activities, IFN-γ also exerts anti-proliferative, immunoregulatory, and proinflammatory activities. IFN-γ can upregulate MHC class I and II antigen expression by antigen-presenting cells.
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 500 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
Submitted references TNF-alpha drives human CD14+ monocytes to differentiate into CD70+ dendritic cells evoking Th1 and Th17 responses.
Iwamoto S, Iwai S, Tsujiyama K, Kurahashi C, Takeshita K, Naoe M, Masunaga A, Ogawa Y, Oguchi K, Miyazaki A
Journal of immunology (Baltimore, Md. : 1950) 2007 Aug 1;179(3):1449-57
Journal of immunology (Baltimore, Md. : 1950) 2007 Aug 1;179(3):1449-57
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- PMA/Ionomycin-stimulated human PBMCs were stained with CD3 PE/Cy5 and 4S.B3 PE
- Conjugate
- Unconjugated
