FNab10134

antibody from FineTest Biotech

Targeting: RAD51 BRCC5, FANCR, HsRad51, HsT16930, RAD51A, RECA

ELISA

Immunohistochemistry

Antibody data

Submit

Validation data

Product number: FNab10134 - Provider product page
Provider: FineTest Biotech
Product name: RAD51 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange(PubMed:26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: RAD51 homolog
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

RAD51 protein structure - FNab10134 shown in red.