310408

antibody from BioLegend
Targeting: IL9R CD129
Provider product page for 310408
ELISA
Flow cytometry
Blocking/Neutralizing

Antibody data

Product number
310408 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#310408, RRID:AB_314821
Product name
LEAF™ anti-human CD129 (IL-9 R) [AH9R7]
Antibody type
Monoclonal
Antigen
CD129 (IL-9 R)
Description
CD129 is known as the 57 kD IL-9 receptor. It is a member of the hematopoietin receptor superfamily. Although the α-chain of the receptor binds IL-9 with high affinity, interaction with the γ-chain (CD132) of the IL-2 receptor is required for signaling. The IL-9 receptor is expressed at low levels on eosinophils, mast cells, macrophages, B lymphocytes, T lymphocytes, and erythroid progenitors. IL-9 receptor binding initiates STAT activation required for the proliferative and anti-apoptotic effects of this cytokine. In humans, signals from the IL-9 receptor appear to be critical for intrathymic T cell development. IL-9 binding has been shown to increase IL-5 receptor expression and promote survival in human eosinophils.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
500 µg
Concentration
1 mg/ml
Storage
The antibody solution should be stored undiluted at 4 °C. This LEAF™ solution contains no preservative; handle under aseptic conditions.
IL9R protein structure - 310408 shown in red.