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Western blot
ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- 633301 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#633301, RRID:AB_2078706
- Product name
- Purified anti-Cdk4
- Antibody type
- Polyclonal
- Antigen
- Peptide mapping to the carboxy terminus of mouse Cdk4
- Description
- Cdk4 (Cyclin dependent kinase 4) belongs to the Ser/Thr protein kinase superfamily, CDC2/CDKX subfamily,and predicted molecular weight 34 kD. The complexes formed by CDK4 and the D-type cyclins are involved in the control of cell proliferation during the G1 phase. D-type cyclins are induced by mitogens and activated Cdk4/cyclin D complexes are thought to phosphorylate the retinoblastoma susceptibility protein (Rb), thereby facilitating G, progression. The Poly6333 antibody has been shown to be useful for western blotting, immunoprecipitation, and immunohistochemistry of human, mouse, and rat Cdk4 protein.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Vial size
- 125 µl
- Storage
- The antibody solution should be stored undiluted at 4°C. DO NOT FREEZE.
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Western blot analysis of extracts from Hela cells, using anti-Cdk4, Poly6333.
- Conjugate
- Unconjugated
