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Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- 11236-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11236-2-AP, RRID:AB_2103285
- Product name
- FLCN antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FLCN antibody (Cat. #11236-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Methionine-chelated Zn promotes anabolism by integrating mTOR signal and autophagy pathway in juvenile yellow catfish.
FLCN Regulates HIF2α Nuclear Import and Proliferation of Clear Cell Renal Cell Carcinoma.
AMPK promotes induction of the tumor suppressor FLCN through activation of TFEB independently of mTOR.
Stabilization of MAPO1 by specific binding with folliculin and AMP-activated protein kinase in O⁶-methylguanine-induced apoptosis.
Activation of AMP-activated protein kinase by MAPO1 and FLCN induces apoptosis triggered by alkylated base mismatch in DNA.
Wu K, Chen GH, Hogstrand C, Ling SC, Wu LX, Luo Z
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2021 May;65:126732
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2021 May;65:126732
FLCN Regulates HIF2α Nuclear Import and Proliferation of Clear Cell Renal Cell Carcinoma.
Zhao X, Ma Y, Cui J, Zhao H, Liu L, Wang Y, Min P, Zhang L, Chen Y, Du J, Zhang Y, Gu L
Frontiers in molecular biosciences 2020;7:121
Frontiers in molecular biosciences 2020;7:121
AMPK promotes induction of the tumor suppressor FLCN through activation of TFEB independently of mTOR.
Collodet C, Foretz M, Deak M, Bultot L, Metairon S, Viollet B, Lefebvre G, Raymond F, Parisi A, Civiletto G, Gut P, Descombes P, Sakamoto K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Nov;33(11):12374-12391
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Nov;33(11):12374-12391
Stabilization of MAPO1 by specific binding with folliculin and AMP-activated protein kinase in O⁶-methylguanine-induced apoptosis.
Sano S, Sakagami R, Sekiguchi M, Hidaka M
Biochemical and biophysical research communications 2013 Jan 11;430(2):810-5
Biochemical and biophysical research communications 2013 Jan 11;430(2):810-5
Activation of AMP-activated protein kinase by MAPO1 and FLCN induces apoptosis triggered by alkylated base mismatch in DNA.
Lim TH, Fujikane R, Sano S, Sakagami R, Nakatsu Y, Tsuzuki T, Sekiguchi M, Hidaka M
DNA repair 2012 Mar 1;11(3):259-66
DNA repair 2012 Mar 1;11(3):259-66
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse thymus tissue were subjected to SDS PAGE followed by western blot with 11236-2-AP(FLCN antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP result of anti-FLCN(11236-2-AP) with Hela cell.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human ovary tumor using 11236-2-AP(FLCN antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
