Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 15513-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15513-1-AP, RRID:AB_2206563
- Product name
- Cardiac Troponin T antibody
- Antibody type
- Polyclonal
- Description
- Cardiac Troponin T antibody (Cat. #15513-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Engineering extracellular vesicles with platelet membranes fusion enhanced targeted therapeutic angiogenesis in a mouse model of myocardial ischemia reperfusion.
Direct in vivo reprogramming with non-viral sequential targeting nanoparticles promotes cardiac regeneration.
Platelet-Like Fusogenic Liposome-Mediated Targeting Delivery of miR-21 Improves Myocardial Remodeling by Reprogramming Macrophages Post Myocardial Ischemia-Reperfusion Injury.
5-Azacytidine-Induced Cardiomyocyte Differentiation of Very Small Embryonic-Like Stem Cells.
Poly(I:C) preconditioning protects the heart against myocardial ischemia/reperfusion injury through TLR3/PI3K/Akt-dependent pathway.
Elevated myocardial SORBS2 and the underlying implications in left ventricular noncompaction cardiomyopathy.
miR-25 Promotes Cardiomyocyte Proliferation by Targeting FBXW7.
Intrinsic Color Sensing System Allows for Real-Time Observable Functional Changes on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Enrichment differentiation of human induced pluripotent stem cells into sinoatrial node-like cells by combined modulation of BMP, FGF, and RA signaling pathways.
Rare mutations of ADAM17 from TOFs induce hypertrophy in human embryonic stem cell-derived cardiomyocytes via HB-EGF signaling.
Regulation of Histone Acetylation on Expression Profiles of Potassium Channels During Cardiomyocyte Differentiation From Mouse Embryonic Stem Cells.
Insulin-like growth factor binding protein 4 enhances cardiomyocytes induction in murine-induced pluripotent stem cells.
Cardiac function is regulated by B56α-mediated targeting of protein phosphatase 2A (PP2A) to contractile relevant substrates.
A multifunctional protein, EWS, is essential for early brown fat lineage determination.
Knockdown of nucleosome assembly protein 1-like 1 promotes dimethyl sulfoxide-induced differentiation of P19CL6 cells into cardiomyocytes.
Li Q, Song Y, Wang Q, Chen J, Gao J, Tan H, Li S, Wu Y, Yang H, Huang H, Yu Y, Li Y, Zhang N, Huang Z, Pang Z, Qian J, Ge J
Theranostics 2021;11(8):3916-3931
Theranostics 2021;11(8):3916-3931
Direct in vivo reprogramming with non-viral sequential targeting nanoparticles promotes cardiac regeneration.
Wang Q, Song Y, Chen J, Li Q, Gao J, Tan H, Zhu Y, Wang Z, Li M, Yang H, Zhang N, Li X, Qian J, Pang Z, Huang Z, Ge J
Biomaterials 2021 Sep;276:121028
Biomaterials 2021 Sep;276:121028
Platelet-Like Fusogenic Liposome-Mediated Targeting Delivery of miR-21 Improves Myocardial Remodeling by Reprogramming Macrophages Post Myocardial Ischemia-Reperfusion Injury.
Tan H, Song Y, Chen J, Zhang N, Wang Q, Li Q, Gao J, Yang H, Dong Z, Weng X, Wang Z, Sun D, Yakufu W, Pang Z, Huang Z, Ge J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Aug;8(15):e2100787
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Aug;8(15):e2100787
5-Azacytidine-Induced Cardiomyocyte Differentiation of Very Small Embryonic-Like Stem Cells.
Sun X, Li H, Zhu Y, Xu P, Zuo Q, Li B, Gu X
Stem cells international 2020;2020:5162350
Stem cells international 2020;2020:5162350
Poly(I:C) preconditioning protects the heart against myocardial ischemia/reperfusion injury through TLR3/PI3K/Akt-dependent pathway.
Chen E, Chen C, Niu Z, Gan L, Wang Q, Li M, Cai X, Gao R, Katakam S, Chen H, Zhang S, Zhou R, Cheng X, Qiu Y, Yu H, Zhu T, Liu J
Signal transduction and targeted therapy 2020 Nov 6;5(1):216
Signal transduction and targeted therapy 2020 Nov 6;5(1):216
Elevated myocardial SORBS2 and the underlying implications in left ventricular noncompaction cardiomyopathy.
Li C, Liu F, Liu S, Pan H, Du H, Huang J, Xie Y, Li Y, Zhao R, Wei Y
EBioMedicine 2020 Mar;53:102695
EBioMedicine 2020 Mar;53:102695
miR-25 Promotes Cardiomyocyte Proliferation by Targeting FBXW7.
Wang B, Xu M, Li M, Wu F, Hu S, Chen X, Zhao L, Huang Z, Lan F, Liu D, Wang Y
Molecular therapy. Nucleic acids 2020 Mar 6;19:1299-1308
Molecular therapy. Nucleic acids 2020 Mar 6;19:1299-1308
Intrinsic Color Sensing System Allows for Real-Time Observable Functional Changes on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Gong Y, Chen Z, Yang L, Ai X, Yan B, Wang H, Qiu L, Tan Y, Witman N, Wang W, Zhao Y, Fu W
ACS nano 2020 Jul 28;14(7):8232-8246
ACS nano 2020 Jul 28;14(7):8232-8246
Enrichment differentiation of human induced pluripotent stem cells into sinoatrial node-like cells by combined modulation of BMP, FGF, and RA signaling pathways.
Liu F, Fang Y, Hou X, Yan Y, Xiao H, Zuo D, Wen J, Wang L, Zhou Z, Dang X, Zhou R, Liao B
Stem cell research & therapy 2020 Jul 16;11(1):284
Stem cell research & therapy 2020 Jul 16;11(1):284
Rare mutations of ADAM17 from TOFs induce hypertrophy in human embryonic stem cell-derived cardiomyocytes via HB-EGF signaling.
Xie Y, Ma A, Wang B, Peng R, Jing Y, Wang D, Finnell RH, Qiao B, Wang Y, Wang H, Zheng Y
Clinical science (London, England : 1979) 2019 Jan 31;133(2):225-238
Clinical science (London, England : 1979) 2019 Jan 31;133(2):225-238
Regulation of Histone Acetylation on Expression Profiles of Potassium Channels During Cardiomyocyte Differentiation From Mouse Embryonic Stem Cells.
Wang D, Liu C, Li Z, Wang Y, Wang W, Wu X, Wang K, Miao W, Li L, Peng L
Journal of cellular biochemistry 2017 Dec;118(12):4460-4467
Journal of cellular biochemistry 2017 Dec;118(12):4460-4467
Insulin-like growth factor binding protein 4 enhances cardiomyocytes induction in murine-induced pluripotent stem cells.
Xue Y, Yan Y, Gong H, Fang B, Zhou Y, Ding Z, Yin P, Zhang G, Ye Y, Yang C, Ge J, Zou Y
Journal of cellular biochemistry 2014 Sep;115(9):1495-504
Journal of cellular biochemistry 2014 Sep;115(9):1495-504
Cardiac function is regulated by B56α-mediated targeting of protein phosphatase 2A (PP2A) to contractile relevant substrates.
Kirchhefer U, Brekle C, Eskandar J, Isensee G, Kučerová D, Müller FU, Pinet F, Schulte JS, Seidl MD, Boknik P
The Journal of biological chemistry 2014 Dec 5;289(49):33862-73
The Journal of biological chemistry 2014 Dec 5;289(49):33862-73
A multifunctional protein, EWS, is essential for early brown fat lineage determination.
Park JH, Kang HJ, Kang SI, Lee JE, Hur J, Ge K, Mueller E, Li H, Lee BC, Lee SB
Developmental cell 2013 Aug 26;26(4):393-404
Developmental cell 2013 Aug 26;26(4):393-404
Knockdown of nucleosome assembly protein 1-like 1 promotes dimethyl sulfoxide-induced differentiation of P19CL6 cells into cardiomyocytes.
Li L, Gong H, Yu H, Liu X, Liu Q, Yan G, Zhang Y, Lu H, Zou Y, Yang P
Journal of cellular biochemistry 2012 Dec;113(12):3788-96
Journal of cellular biochemistry 2012 Dec;113(12):3788-96
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 15513-1-AP(TNNT2 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using TNNT2 antibody 15513-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 15513-1-AP(TNNT2 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue