Antibody data

Product number
BS60441 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PI3K p110Ñ´ polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human PI3K p110Ñ´.
Description
Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85Ï« and p85ÉÇ), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110Ï« and p110ÉÇ interact with p85Ï«, and p110Ï« has also been shown to interact with p85ÉÇ in vitro. p110Ñ´ expression is restricted to white blood cells. It has been shown to bind p85Ï« and ÉÇ, but it apparently does not phosphorylate these subunits. p110Ñ´ seems to have the capacity to autophosphorylate. p110ÎÛ does not interact with the p85 subunits. It has been shown to be activated by Ï« and ÉÇÎÛ heterotrimeric G proteins.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PIK3CD protein structure - BS60441 shown in red.