AMM00481G

antibody from Leading Biology

Targeting: CD47 IAP, MER6, OA3

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

AMM00481G

Provider

Leading Biology

Product name

CD47 / IAP (Integrin Associated Protein) Antibody - Without BSA and Azide

Antibody type

Monoclonal

Description

This antibody reacts with Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus.Ā CD47 may play a role in membrane transport and/or integrin dependent signal transduction.Ā

Reactivity

Human, Mouse

Host

Mouse

Antibody clone number

B6H12.2

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.