APG01029G

antibody from Leading Biology

Targeting: TFAP2C AP2-GAMMA, ERF1, hAP-2g, TFAP2G

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

APG01029G

Provider

Leading Biology

Product name

TFAP2C / AP2 Gamma Antibody (C-Terminus)

Antibody type

Polyclonal

Description

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

Reactivity

Human, Rabbit, Simian

Host

Goat

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.