Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- GTX116046 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX116046, RRID:AB_2036140
- Product name
- MRP1 antibody [N1N2], N-term
- Antibody type
- Polyclonal
- Reactivity
- Human
- Host
- Rabbit
Submitted references Increase in resistance to anticancer drugs involves occludin in spheroid culture model of lung adenocarcinoma A549 cells.
Elevation of sensitivity to anticancer agents of human lung adenocarcinoma A549 cells by knockdown of claudin-2 expression in monolayer and spheroid culture models.
Modulation of the mRNA-binding protein HuR as a novel reversal mechanism of epirubicin-triggered multidrug resistance in colorectal cancer cells.
MEK inhibitor enhances sensitivity to chemotherapeutic drugs in multidrug resistant hepatocellular carcinoma cells.
Salvianolic acid A reverses paclitaxel resistance in human breast cancer MCF-7 cells via targeting the expression of transgelin 2 and attenuating PI3 K/Akt pathway
Paeonol reverses paclitaxel resistance in human breast cancer cells by regulating the expression of transgelin 2.
Proteomic analysis of the proteins that are associated with the resistance to paclitaxel in human breast cancer cells.
Eguchi H, Akizuki R, Maruhashi R, Tsukimoto M, Furuta T, Matsunaga T, Endo S, Ikari A
Scientific reports 2018 Oct 11;8(1):15157
Scientific reports 2018 Oct 11;8(1):15157
Elevation of sensitivity to anticancer agents of human lung adenocarcinoma A549 cells by knockdown of claudin-2 expression in monolayer and spheroid culture models.
Maruhashi R, Akizuki R, Sato T, Matsunaga T, Endo S, Yamaguchi M, Yamazaki Y, Sakai H, Ikari A
Biochimica et biophysica acta. Molecular cell research 2018 Mar;1865(3):470-479
Biochimica et biophysica acta. Molecular cell research 2018 Mar;1865(3):470-479
Modulation of the mRNA-binding protein HuR as a novel reversal mechanism of epirubicin-triggered multidrug resistance in colorectal cancer cells.
Lin GL, Ting HJ, Tseng TC, Juang V, Lo YL
PloS one 2017;12(10):e0185625
PloS one 2017;12(10):e0185625
MEK inhibitor enhances sensitivity to chemotherapeutic drugs in multidrug resistant hepatocellular carcinoma cells.
Meng Q, He X, Xie G, Tian Q, Shu X, Li J, Xiao Y
Oncology letters 2017 Sep;14(3):3089-3095
Oncology letters 2017 Sep;14(3):3089-3095
Salvianolic acid A reverses paclitaxel resistance in human breast cancer MCF-7 cells via targeting the expression of transgelin 2 and attenuating PI3 K/Akt pathway
Cai J, Chen S, Zhang W, Zheng X, Hu S, Pang C, Lu J, Xing J, Dong Y
Phytomedicine 2014 October;21(12):1725-1732
Phytomedicine 2014 October;21(12):1725-1732
Paeonol reverses paclitaxel resistance in human breast cancer cells by regulating the expression of transgelin 2.
Cai J, Chen S, Zhang W, Hu S, Lu J, Xing J, Dong Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2014 Jun 15;21(7):984-91
Phytomedicine : international journal of phytotherapy and phytopharmacology 2014 Jun 15;21(7):984-91
Proteomic analysis of the proteins that are associated with the resistance to paclitaxel in human breast cancer cells.
Chen S, Dong Q, Hu S, Cai J, Zhang W, Sun J, Wang T, Xie J, He H, Xing J, Lu J, Dong Y
Molecular bioSystems 2014 Feb;10(2):294-303
Molecular bioSystems 2014 Feb;10(2):294-303
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (30 ?g of whole cell lysate) A: A431 (GTX27909) 5% SDS PAGE GTX116046 diluted at 1:1000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded BT483 xenograft, using MRP1(GTX116046) antibody at 1:250 dilution.