Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [4]
- Immunocytochemistry [1]
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Validation data
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- Product number
- TA309559 - Provider product page
- Provider
- OriGene
- Product name
- Mouse Monoclonal MRP1 Antibody (IU2H10)
- Antibody type
- Monoclonal
- Description
- Mouse Monoclonal MRP1 Antibody (IU2H10)
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- IU2H10
- Vial size
- 0.1ml
Submitted references Involvement of miR-133a and miR-326 in ADM resistance of HepG2 through modulating expression of ABCC1.
Multidrug Resistance-Associated Protein 4 (MRP4/ABCC4) Controls Efflux Transport of Hesperetin Sulfates in Sulfotransferase 1A3-Overexpressing Human Embryonic Kidney 293 Cells.
Characterization of chrysin glucuronidation in UGT1A1-overexpressing HeLa cells: elucidating the transporters responsible for efflux of glucuronide.
Stable knock-down of efflux transporters leads to reduced glucuronidation in UGT1A1-overexpressing HeLa cells: the evidence for glucuronidation-transport interplay.
Ma J, Wang T, Guo R, Yang X, Yin J, Yu J, Xiang Q, Pan X, Tang H, Lei X
Journal of drug targeting 2015;23(6):519-24
Journal of drug targeting 2015;23(6):519-24
Multidrug Resistance-Associated Protein 4 (MRP4/ABCC4) Controls Efflux Transport of Hesperetin Sulfates in Sulfotransferase 1A3-Overexpressing Human Embryonic Kidney 293 Cells.
Sun H, Wang X, Zhou X, Lu D, Ma Z, Wu B
Drug metabolism and disposition: the biological fate of chemicals 2015 Oct;43(10):1430-40
Drug metabolism and disposition: the biological fate of chemicals 2015 Oct;43(10):1430-40
Characterization of chrysin glucuronidation in UGT1A1-overexpressing HeLa cells: elucidating the transporters responsible for efflux of glucuronide.
Quan E, Wang H, Dong D, Zhang X, Wu B
Drug metabolism and disposition: the biological fate of chemicals 2015 Apr;43(4):433-43
Drug metabolism and disposition: the biological fate of chemicals 2015 Apr;43(4):433-43
Stable knock-down of efflux transporters leads to reduced glucuronidation in UGT1A1-overexpressing HeLa cells: the evidence for glucuronidation-transport interplay.
Zhang X, Dong D, Wang H, Ma Z, Wang Y, Wu B
Molecular pharmaceutics 2015 Apr 6;12(4):1268-78
Molecular pharmaceutics 2015 Apr 6;12(4):1268-78
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Supportive validation
- Submitted by
- OriGene (provider)
- Main image
- Experimental details
- Western Blot: MRP1 Antibody (IU2H10) - Western Blot detection of MRP1 1: Vector-transfected HEK293 cells 2: MRP1-transfected cells, prep1 3: MRP1-transfected cells, prep2 (the lower band is a degradation product.
- Validation comment
- WB
- Submitted by
- OriGene (provider)
- Main image
- Experimental details
- Figure from citation: Western blot analysis of protein expression of BCRP and four MRP family transporters by using anti-ABCG2, anti-ABCC1, anti-ABCC2, anti-ABCC3 and anti-ABCC4 antibody in HeLa and HeLa1A5 cells.
- Validation comment
- WB
- Submitted by
- OriGene (provider)
- Main image
- Experimental details
- Figure from citation: Western blot analysis of ABCC1 protein level by using anti-ABCC1 antibody in miR-133a and miR-326 mimic-transfected HepG2 cells were down-regulated in comparison with control cells and untreated cells.
- Validation comment
- WB
- Submitted by
- OriGene (provider)
- Main image
- Experimental details
- Figure from citation: Western blot analysis of human BCRP, MRP1, MRP3, MRP7 and UGT1A1 protein expression by using anti-ABCG2, anti-ABCC1, anti-ABCC3, anti-ABCC4 and anti-UGT1A1 antibody in various cell lines.
- Validation comment
- WB
Supportive validation
- Submitted by
- OriGene (provider)
- Main image
- Experimental details
- Immunocytochemistry: MRP1 Antibody (IU2H10) - Detection of MRP1 (Green) using anti-MRP1 in Hela cells. Nuclei (Blue) are counterstained with Hoechst 33258.
- Validation comment
- IF