Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Immunohistochemistry [2]
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Validation data
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- Product number
- NBP2-44441-0.1mg - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal AMPD3 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. It recognizes a protein of ~90kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C.
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: AMPD3 Antibody (AMPD3/901) [NBP2-44441] - Human Placenta stained with AMPD3 Monoclonal Antibody (AMPD3/901)
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- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: AMPD3 Antibody (AMPD3/901) [NBP2-44441] - Human Tonsil stained with AMPD3 Monoclonal Antibody (AMPD3/901)