APR04009G

antibody from Leading Biology

Targeting: SEPTIN5 H5, HCDCREL-1, PNUTL1, SEPT5

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

APR04009G

Provider

Leading Biology

Product name

SEPT5 Antibody (N-term)

Antibody type

Polyclonal

Description

This gene is a member of the septin gene family ofnucleotide binding proteins, originally described in yeast as celldivision cycle regulatory proteins. Septins are highly conserved inyeast, Drosophila, and mouse and appear to regulate cytoskeletalorganization. Disruption of septin function disturbs cytokinesisand results in large multinucleate or polyploid cells. This gene ismapped to 22q11, the region frequently deleted in DiGeorge andvelocardiofacial syndromes. A translocation involving the MLL geneand this gene has also been reported in patients with acute myeloidleukemia. Alternative splicing results in multiple transcriptvariants. The presence of a non-consensus polyA signal (AACAAT) inthis gene also results in read-through transcription into thedownstream neighboring gene (GP1BB; platelet glycoprotein Ib),whereby larger, non-coding transcripts are produced. [provided byRefSeq].

Reactivity

Human

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.