GTX42439

antibody from GeneTex

Targeting: TNFRSF4 ACT35, CD134, OX40, TXGP1L

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

GTX42439

Provider

GeneTex

Proper citation

GeneTex Cat#GTX42439, RRID:AB_11167829

Product name

CD134 antibody [OX-40]

Antibody type

Monoclonal

Reactivity

Rat

Host

Mouse

References

Submitted references

OX40 ligand fusion protein delivered simultaneously with the BCG vaccine provides superior protection against murine Mycobacterium tuberculosis infection.

Snelgrove RJ, Cornere MM, Edwards L, Dagg B, Keeble J, Rodgers A, Lyonga DE, Stewart GR, Young DB, Walker B, Hussell T
The Journal of infectious diseases 2012 Mar 15;205(6):975-83

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T cell vaccination induces the elimination of EAE effector T cells: analysis using GFP-transduced, encephalitogenic T cells.

Volovitz I, Marmor Y, Mor F, Flügel A, Odoardi F, Eisenbach L, Cohen IR
Journal of autoimmunity 2010 Sep;35(2):135-44

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Immune responses elicited in tertiary lymphoid tissues display distinctive features.

Thaunat O, Graff-Dubois S, Brouard S, Gautreau C, Varthaman A, Fabien N, Field AC, Louedec L, Dai J, Joly E, Morelon E, Soulillou JP, Michel JB, Nicoletti A
PloS one 2010 Jun 30;5(6):e11398

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The biological response modifier AM3 attenuates the inflammatory cell response and hepatic fibrosis in rats with biliary cirrhosis.

Albillos A, Nieto M, Ubeda M, Muñoz L, Fraile B, Reyes E, Lledó L, Blanco I, Pastor O, Salas C, Lario M, Monserrat J, Bataller R, Alvarez-Mon M
Gut 2010 Jul;59(7):943-52

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Blockade of chronic graft-versus-host disease by alloantigen-induced CD4+CD25+Foxp3+ regulatory T cells in nonlymphopenic hosts.

Giorgini A, Noble A
Journal of leukocyte biology 2007 Nov;82(5):1053-61

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Eosinophilic bowel disease controlled by the BB rat-derived lymphopenia/Gimap5 gene.

Cousins L, Graham M, Tooze R, Carter C, Miller JR, Powrie FM, Macpherson GG, Butcher GW
Gastroenterology 2006 Nov;131(5):1475-85

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Phenotypic characterization of regulatory CD4+CD25+ T cells in rats.

Stephens LA, Barclay AN, Mason D
International immunology 2004 Feb;16(2):365-75

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Cholera toxin promotes the induction of regulatory T cells specific for bystander antigens by modulating dendritic cell activation.

Lavelle EC, McNeela E, Armstrong ME, Leavy O, Higgins SC, Mills KH
Journal of immunology (Baltimore, Md. : 1950) 2003 Sep 1;171(5):2384-92

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A critical role for OX40 in T cell-mediated immunopathology during lung viral infection.

Humphreys IR, Walzl G, Edwards L, Rae A, Hill S, Hussell T
The Journal of experimental medicine 2003 Oct 20;198(8):1237-42

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Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers.

Walker LS, Gulbranson-Judge A, Flynn S, Brocker T, Raykundalia C, Goodall M, Förster R, Lipp M, Lane P
The Journal of experimental medicine 1999 Oct 18;190(8):1115-22

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Immunocytochemical study of retinal diode laser photocoagulation in the rat.

Richardson PR, Boulton ME, Duvall-Young J, McLeod D
The British journal of ophthalmology 1996 Dec;80(12):1092-8

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Characterization of the MRC OX40 antigen of activated CD4 positive T lymphocytes--a molecule related to nerve growth factor receptor.

Mallett S, Fossum S, Barclay AN
The EMBO journal 1990 Apr;9(4):1063-8

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Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts.

Paterson DJ, Jefferies WA, Green JR, Brandon MR, Corthesy P, Puklavec M, Williams AF
Molecular immunology 1987 Dec;24(12):1281-90

Flow cytometry

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Staining of stimulated rat spleen cells with Mouse anti Rat CD134:FITC (GTX76450)