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- References [22]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 11293-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11293-1-AP, RRID:AB_2109970
- Product name
- ALR antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ALR antibody (Cat. #11293-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Grx2 Regulates Skeletal Muscle Mitochondrial Structure and Autophagy.
Bisphenol-A inhibits mitochondrial biogenesis via impairment of GFER mediated mitochondrial protein import in the rat brain hippocampus.
Alleviation of CCCP-induced mitochondrial injury by augmenter of liver regeneration via the PINK1/Parkin pathway-dependent mitophagy.
Augmenter of liver regeneration ameliorates ischemia-reperfusion injury in steatotic liver via inhibition of the TLR4/NF-κB pathway.
Augmenter of liver regeneration regulates cellular iron homeostasis by modulating mitochondrial transport of ATP-binding cassette B8.
Dependence of PINK1 accumulation on mitochondrial redox system.
Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal.
Lack of Augmenter of Liver Regeneration Disrupts Cholesterol Homeostasis of Liver in Mice by Inhibiting the AMPK Pathway.
Augmenter of liver regeneration protein deficiency promotes hepatic steatosis by inducing oxidative stress and microRNA-540 expression.
Deficiency in augmenter of liver regeneration accelerates liver fibrosis by promoting migration of hepatic stellate cell.
Lack of hepatic stimulator substance expression promotes hepatocellular carcinoma metastasis partly through ERK-activated epithelial-mesenchymal transition.
Alleviation of palmitic acid-induced endoplasmic reticulum stress by augmenter of liver regeneration through IP3R-controlled Ca2+ release.
Augmenter of liver regeneration potentiates doxorubicin anticancer efficacy by reducing the expression of ABCB1 and ABCG2 in hepatocellular carcinoma.
Hepatic stimulator substance resists hepatic ischemia/reperfusion injury by regulating Drp1 translocation and activation.
Hepatic Deficiency of Augmenter of Liver Regeneration Exacerbates Alcohol-Induced Liver Injury and Promotes Fibrosis in Mice.
Altered redox mitochondrial biology in the neurodegenerative disorder fragile X-tremor/ataxia syndrome: use of antioxidants in precision medicine.
Augmenter of Liver Regeneration Gene Therapy Using a Novel Minicircle DNA Vector Alleviates Liver Fibrosis in Rats.
Augmenter of liver regeneration (ALR) restrains concanavalin A-induced hepatitis in mice.
The Level of ALR is Regulated by the Quantity of Mitochondrial DNA.
Megakaryocytic differentiation of K562 cells induced by PMA reduced the activity of respiratory chain complex IV.
Gfer inhibits Jab1-mediated degradation of p27kip1 to restrict proliferation of hematopoietic stem cells.
The mitochondrial disulfide relay system protein GFER is mutated in autosomal-recessive myopathy with cataract and combined respiratory-chain deficiency.
Liaghati A, Pileggi CA, Parmar G, Patten DA, Hadzimustafic N, Cuillerier A, Menzies KJ, Burelle Y, Harper ME
Frontiers in physiology 2021;12:604210
Frontiers in physiology 2021;12:604210
Bisphenol-A inhibits mitochondrial biogenesis via impairment of GFER mediated mitochondrial protein import in the rat brain hippocampus.
Goyal S, Tiwari S, Seth B, Tandon A, Shankar J, Sinha M, Singh SJ, Priya S, Chaturvedi RK
Neurotoxicology 2021 Jul;85:18-32
Neurotoxicology 2021 Jul;85:18-32
Alleviation of CCCP-induced mitochondrial injury by augmenter of liver regeneration via the PINK1/Parkin pathway-dependent mitophagy.
Zhang J, Chen S, Li Y, Xiao W, An W
Experimental cell research 2021 Dec 1;409(1):112866
Experimental cell research 2021 Dec 1;409(1):112866
Augmenter of liver regeneration ameliorates ischemia-reperfusion injury in steatotic liver via inhibition of the TLR4/NF-κB pathway.
Weng J, Wang X, Xu B, Li W
Experimental and therapeutic medicine 2021 Aug;22(2):863
Experimental and therapeutic medicine 2021 Aug;22(2):863
Augmenter of liver regeneration regulates cellular iron homeostasis by modulating mitochondrial transport of ATP-binding cassette B8.
Chang HC, Shapiro JS, Jiang X, Senyei G, Sato T, Geier J, Sawicki KT, Ardehali H
eLife 2021 Apr 9;10
eLife 2021 Apr 9;10
Dependence of PINK1 accumulation on mitochondrial redox system.
Gao F, Zhang Y, Hou X, Tao Z, Ren H, Wang G
Aging cell 2020 Sep;19(9):e13211
Aging cell 2020 Sep;19(9):e13211
Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal.
Singh RP, Jeyaraju DV, Voisin V, Hurren R, Xu C, Hawley JR, Barghout SH, Khan DH, Gronda M, Wang X, Jitkova Y, Sharon D, Liyanagae S, MacLean N, Seneviratene AK, Mirali S, Borenstein A, Thomas GE, Soriano J, Orouji E, Minden MD, Arruda A, Chan SM, Bader GD, Lupien M, Schimmer AD
Cell stem cell 2020 Jun 4;26(6):926-937.e10
Cell stem cell 2020 Jun 4;26(6):926-937.e10
Lack of Augmenter of Liver Regeneration Disrupts Cholesterol Homeostasis of Liver in Mice by Inhibiting the AMPK Pathway.
Wang X, Dong LY, Gai QJ, Ai WL, Wu Y, Xiao WC, Zhang J, An W
Hepatology communications 2020 Aug;4(8):1149-1167
Hepatology communications 2020 Aug;4(8):1149-1167
Augmenter of liver regeneration protein deficiency promotes hepatic steatosis by inducing oxidative stress and microRNA-540 expression.
Kumar S, Rani R, Karns R, Gandhi CR
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Mar;33(3):3825-3840
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Mar;33(3):3825-3840
Deficiency in augmenter of liver regeneration accelerates liver fibrosis by promoting migration of hepatic stellate cell.
Ai WL, Dong LY, Wang J, Li ZW, Wang X, Gao J, Wu Y, An W
Biochimica et biophysica acta. Molecular basis of disease 2018 Nov;1864(11):3780-3791
Biochimica et biophysica acta. Molecular basis of disease 2018 Nov;1864(11):3780-3791
Lack of hepatic stimulator substance expression promotes hepatocellular carcinoma metastasis partly through ERK-activated epithelial-mesenchymal transition.
Jia XW, Li ZW, Dong LY, Sun GY, Wang X, Gao J, Li YP, Wu Y, An W
Laboratory investigation; a journal of technical methods and pathology 2018 Jul;98(7):871-882
Laboratory investigation; a journal of technical methods and pathology 2018 Jul;98(7):871-882
Alleviation of palmitic acid-induced endoplasmic reticulum stress by augmenter of liver regeneration through IP3R-controlled Ca2+ release.
Xiao WC, Zhang J, Chen SL, Shi YJ, Xiao F, An W
Journal of cellular physiology 2018 Aug;233(8):6148-6157
Journal of cellular physiology 2018 Aug;233(8):6148-6157
Augmenter of liver regeneration potentiates doxorubicin anticancer efficacy by reducing the expression of ABCB1 and ABCG2 in hepatocellular carcinoma.
Guo YY, Wu Y, Jia XW, An W
Laboratory investigation; a journal of technical methods and pathology 2017 Dec;97(12):1400-1411
Laboratory investigation; a journal of technical methods and pathology 2017 Dec;97(12):1400-1411
Hepatic stimulator substance resists hepatic ischemia/reperfusion injury by regulating Drp1 translocation and activation.
Zhang C, Huang J, An W
Hepatology (Baltimore, Md.) 2017 Dec;66(6):1989-2001
Hepatology (Baltimore, Md.) 2017 Dec;66(6):1989-2001
Hepatic Deficiency of Augmenter of Liver Regeneration Exacerbates Alcohol-Induced Liver Injury and Promotes Fibrosis in Mice.
Kumar S, Wang J, Rani R, Gandhi CR
PloS one 2016;11(1):e0147864
PloS one 2016;11(1):e0147864
Altered redox mitochondrial biology in the neurodegenerative disorder fragile X-tremor/ataxia syndrome: use of antioxidants in precision medicine.
Song G, Napoli E, Wong S, Hagerman R, Liu S, Tassone F, Giulivi C
Molecular medicine (Cambridge, Mass.) 2016 Oct;22:548-559
Molecular medicine (Cambridge, Mass.) 2016 Oct;22:548-559
Augmenter of Liver Regeneration Gene Therapy Using a Novel Minicircle DNA Vector Alleviates Liver Fibrosis in Rats.
Wu X, Liu G, Mu M, Peng Y, Li X, Deng L, Zhang Z, Chen M, You S, Kong X
Human gene therapy 2016 Nov;27(11):880-891
Human gene therapy 2016 Nov;27(11):880-891
Augmenter of liver regeneration (ALR) restrains concanavalin A-induced hepatitis in mice.
Mu M, Zhang Z, Cheng Y, Liu G, Chen X, Wu X, Zhuang C, Liu B, Kong X, You S
International immunopharmacology 2016 Jun;35:280-286
International immunopharmacology 2016 Jun;35:280-286
The Level of ALR is Regulated by the Quantity of Mitochondrial DNA.
Balogh T, Lőrincz T, Stiller I, Mandl J, Bánhegyi G, Szarka A
Pathology oncology research : POR 2016 Apr;22(2):431-7
Pathology oncology research : POR 2016 Apr;22(2):431-7
Megakaryocytic differentiation of K562 cells induced by PMA reduced the activity of respiratory chain complex IV.
Huang R, Zhao L, Chen H, Yin RH, Li CY, Zhan YQ, Zhang JH, Ge CH, Yu M, Yang XM
PloS one 2014;9(5):e96246
PloS one 2014;9(5):e96246
Gfer inhibits Jab1-mediated degradation of p27kip1 to restrict proliferation of hematopoietic stem cells.
Teng EC, Todd LR, Ribar TJ, Lento W, Dimascio L, Means AR, Sankar U
Molecular biology of the cell 2011 Apr 15;22(8):1312-20
Molecular biology of the cell 2011 Apr 15;22(8):1312-20
The mitochondrial disulfide relay system protein GFER is mutated in autosomal-recessive myopathy with cataract and combined respiratory-chain deficiency.
Di Fonzo A, Ronchi D, Lodi T, Fassone E, Tigano M, Lamperti C, Corti S, Bordoni A, Fortunato F, Nizzardo M, Napoli L, Donadoni C, Salani S, Saladino F, Moggio M, Bresolin N, Ferrero I, Comi GP
American journal of human genetics 2009 May;84(5):594-604
American journal of human genetics 2009 May;84(5):594-604
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A375 cells were subjected to SDS PAGE followed by western blot with 11293-1-AP(GFER antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ALR antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ALR. This antibody recognizes human,mouse,rat antigen. The ALR antibody has been validated for the following applications: ELISA, WB, IHC analysis.
