BS1653

antibody from Bioworld Technology, Inc

Targeting: MT-CO2 CO2, COX2, MTCO2

Western blot (Data presented on provider website)

Antibody Data

Product number

BS1653

Provider

Bioworld Technology, Inc

Product name

COXII polyclonal antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide corresponding to amino acids 49-63 of Mouse COXII.

Description

Prostaglandins are a diverse group of autocrine and paracrine hormones that mediate many cellular and physiologic processes. Prostaglandin H2 (PGH2) is an intermediate molecule in formation of the prostaglandins. Cyclooxygenase-1 (Cox-1) and cyclooxygenase-2 (Cox-2) are prostaglandin synthases that catalyze the formation of PGH2 from arachidonic acid (AA). Cox-1 and Cox-2 are isozymes of prostaglandin-endoperoxidase synthase (PTGS). Cox-1 is constitutively expressed in most tissues and is thought to serve in general ¡ùhousekeeping¡ì functions. Cox-2 is efficiently induced in migratory cells responding to pro-inflammatory stimuli and is considered to be an important mediator of inflammation. Both enzymes are targets for the nonsteroidal therapeutic anti-inflammatory drugs, NSAIDs .

Reactivity

Human, Mouse

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.